Bioluminescence imaging (BLI) is a technology developed over the past decades (1990's and onward).[1][2][3][when?] that allows for the noninvasive study of ongoing biological processes[4][1][5][6][7] Recently, bioluminescence tomography (BLT) has become possible and several systems have become commercially available. In 2011, PerkinElmer acquired one of the most popular lines of optical imaging systems with bioluminescence from Caliper Life Sciences.[8]
^ abZambito G, Chawda C, Mezzanotte L (August 2021). "Emerging tools for bioluminescence imaging". Current Opinion in Chemical Biology. Chemical Genetics and Epigenetics * Molecular Imaging. 63: 86–94. doi:10.1016/j.cbpa.2021.02.005. PMID 33770744. S2CID 232377256.
^Contag CH, Bachmann MH (2002-08-01). "Advances in in vivo bioluminescence imaging of gene expression". Annual Review of Biomedical Engineering. 4 (1): 235–260. doi:10.1146/annurev.bioeng.4.111901.093336. PMID 12117758.
^Mezzanotte L, van 't Root M, Karatas H, Goun EA, Löwik CW (July 2017). "In Vivo Molecular Bioluminescence Imaging: New Tools and Applications". Trends in Biotechnology. 35 (7): 640–652. doi:10.1016/j.tibtech.2017.03.012. PMID 28501458.
^Brennan CK, Ornelas MY, Yao ZW, Prescher JA (August 2021). "Multicomponent Bioluminescence Imaging with Naphthylamino Luciferins". ChemBioChem. 22 (16): 2650–2654. doi:10.1002/cbic.202100202. PMC 8496354. PMID 34139065.
^Syed AJ, Anderson JC (May 2021). "Applications of bioluminescence in biotechnology and beyond". Chemical Society Reviews. 50 (9): 5668–5705. doi:10.1039/D0CS01492C. PMID 33735357. S2CID 232304401.
^Thorne N, Inglese J, Auld DS (June 2010). "Illuminating insights into firefly luciferase and other bioluminescent reporters used in chemical biology". Chemistry & Biology. 17 (6): 646–657. doi:10.1016/j.chembiol.2010.05.012. PMC 2925662. PMID 20609414.
^Yeh HW, Ai HW (June 2019). "Development and Applications of Bioluminescent and Chemiluminescent Reporters and Biosensors". Annual Review of Analytical Chemistry. 12 (1): 129–150. Bibcode:2019ARAC...12..129Y. doi:10.1146/annurev-anchem-061318-115027. PMC 6565457. PMID 30786216.
^"PerkinElmer to Acquire Caliper Life Sciences for $600M in Cash". Genetic Engineering & Biotechnology News (GEN). Mary Ann Liebert, Inc. 8 September 2011. Retrieved 2016-06-10.
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Bioluminescenceimaging (BLI) is a technology developed over the past decades (1990's and onward).[when?] that allows for the noninvasive study of ongoing...
Bioluminescence is the production and emission of light by living organisms. It is a form of chemiluminescence. Bioluminescence occurs widely in marine...
carry" (ferre). Luciferases are widely used in biotechnology, for bioluminescenceimaging microscopy and as reporter genes, for many of the same applications...
technique. Transgenic mouse models can be imaged by various non-invasive techniques. Bioluminescenceimaging relies on the detection of light produced...
a catalytic reaction, generating bioluminescence. This reaction and the luminescence produced is useful for imaging such as detecting tumors from cancer...
Fluorescence imaging is a type of non-invasive imaging technique that can help visualize biological processes taking place in a living organism. Images can be...
Cherenkov luminescence imaging (CLI) is an emerging imaging modality, similar to bioluminescenceimaging, that captures visible photons emitted by Cherenkov...
"Identification of Inhibitors of ABCG2 by a BioluminescenceImaging-Based High-Throughput Assay". Cancer Res. 69. Bioluminescence Page showing major luciferin types...
clocks in the apparent absence of external stimuli. Although they lack image-forming eyes, their photoreceptors (which detect light) are still functional;...
"Live Cell BioluminescenceImaging in Temporal Reaction of G Protein-Coupled Receptor for High-Throughput Screening and Analysis", Bioluminescence, Methods...
choke off a tumor's blood supply[citation needed]. This form of bioluminescenceimaging allows scientists to test drugs in the pre-clinical stages cheaply...
Biological imaging may refer to any imaging technique used in biology. Typical examples include: Bioluminescenceimaging, a technique for studying laboratory...
1089/153056203772744716. PMID 14980096. Söling A, Rainov NG (October 2003). "Bioluminescenceimaging in vivo - application to cancer research". Expert Opinion on Biological...
resonance imaging (MRI) and computed tomography (CT) are usually used for anatomical imaging, while optical imaging (fluorescence and bioluminescence), positron...
company acquired PRECOS Ltd. (now Crown Bioscience UK Ltd.), and a bioluminescenceimaging platform was established. 2014: Crown Bioscience Taiwan was founded...
Firefly luciferase is the light-emitting enzyme responsible for the bioluminescence of fireflies and click beetles. The enzyme catalyses the oxidation...
causes loss of secondary metabolite production. It is a source for bioluminescenceimaging. Pseudomonas protegens, another insect pathogenic bacterium Boemare...
or examine disease. Bioluminescenceimaging – a technique for studying laboratory animals using luminescent protein. Calcium imaging – determining the calcium...
M.; Droineau, S.; Giovannini, M.; Brémont, M. (April 2006). "BioluminescenceImaging of Live Infected Salmonids Reveals that the Fin Bases are the Major...
and the emission of biophotons is technically a type of bioluminescence, though bioluminescence is generally reserved for higher luminance luciferin/luciferase...
that glow through bioluminescence. They include the European common glow-worm and other members of the Lampyridae, but bioluminescence also occurs in the...
S2CID 37749989. Yan Y, Shi P, Song W, Bi S (2019). "Chemiluminescence and BioluminescenceImaging for Biosensing and Therapy: In Vitro and In Vivo Perspectives"...
Arango, M. E.; Painter, C. L.; Anderes, K. (2009-01-01). "Advancing bioluminescenceimaging technology for the evaluation of anticancer agents in the MDA-MB-435-HAL-Luc...
captured in the North Atlantic - story and imagesImages taken by divers off southern California The Bioluminescence Web Page Divers with huge southern hemisphere...
interferometry, a real-time technique to study biomolecular interactions Bioluminescenceimaging, a technology that allows for the noninvasive study of small laboratory...
related to artery inflammation. SAFI (species altered fluorescence imaging) an imaging technique in electrokinetics and microfluidics. It uses non-electromigrating...
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Molecular imaging is a field of medical imaging that focuses on imaging molecules of medical interest within living patients. This is in contrast to conventional...