RNA polymerase II transcription regulatory region sequence-specific DNA binding
transcription factor binding
nuclear receptor coactivator activity
signaling receptor activity
Cellular component
cytoplasm
nucleoplasm
nucleus
RNA polymerase II transcription regulator complex
Biological process
positive regulation of high-density lipoprotein particle assembly
negative regulation of proteolysis
positive regulation of triglyceride biosynthetic process
positive regulation of protein metabolic process
negative regulation of interferon-gamma-mediated signaling pathway
positive regulation of cholesterol transport
regulation of transcription, DNA-templated
cellular lipid metabolic process
regulation of transcription by RNA polymerase II
positive regulation of secretion of lysosomal enzymes
positive regulation of lipid storage
positive regulation of lipoprotein lipase activity
negative regulation of transcription by RNA polymerase II
positive regulation of fatty acid biosynthetic process
negative regulation of gene expression
transcription, DNA-templated
positive regulation of transcription, DNA-templated
negative regulation of cholesterol storage
negative regulation of pinocytosis
positive regulation of gene expression
retinoic acid receptor signaling pathway
positive regulation of cholesterol efflux
positive regulation of pancreatic juice secretion
lipid homeostasis
negative regulation of lipid transport
transcription initiation from RNA polymerase II promoter
negative regulation of transcription, DNA-templated
negative regulation of macrophage derived foam cell differentiation
positive regulation of transcription by RNA polymerase II
steroid hormone mediated signaling pathway
cholesterol homeostasis
lipid metabolism
multicellular organism development
cell differentiation
cellular response to lipopolysaccharide
negative regulation of cold-induced thermogenesis
intracellular receptor signaling pathway
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
7376
22260
Ensembl
ENSG00000131408
ENSMUSG00000060601
UniProt
P55055
Q60644
RefSeq (mRNA)
NM_007121 NM_001256647
NM_001285517 NM_001285518 NM_001285519 NM_009473
RefSeq (protein)
NP_001243576 NP_009052 NP_009052.3
NP_001272446 NP_001272447 NP_001272448 NP_033499
Location (UCSC)
Chr 19: 50.33 – 50.38 Mb
Chr 7: 44.2 – 44.2 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Liver X receptor beta (LXR-β) is a member of the nuclear receptor family of transcription factors. LXR-β is encoded by the NR1H2 gene (nuclear receptor subfamily 1, group H, member 2).[5]
^ abcGRCh38: Ensembl release 89: ENSG00000131408 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000060601 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Entrez Gene: NR1H2 nuclear receptor subfamily 1, group H, member 2".
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Retinoic acid receptorbeta (RAR-beta), also known as NR1B2 (nuclear receptor subfamily 1, group B, member 2) is a nuclear receptor that in humans is...