One property of a lipid bilayer is the relative mobility (fluidity) of the individual lipid molecules and how this mobility changes with temperature. This response is known as the phase behavior of the bilayer. Broadly, at a given temperature a lipid bilayer can exist in either a liquid or a solid phase. The solid phase is commonly referred to as a “gel” phase. All lipids have a characteristic temperature at which they undergo a transition (melt) from the gel to liquid phase. In both phases the lipid molecules are constrained to the two dimensional plane of the membrane, but in liquid phase bilayers the molecules diffuse freely within this plane. Thus, in a liquid bilayer a given lipid will rapidly exchange locations with its neighbor millions of times a second and will, through the process of a random walk, migrate over long distances.[1]
^H. C. Berg, "Random Walks in Biology". Extended Paperback Ed. ed. 1993, Princeton, NJ: Princeton University Press.
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the phasebehavior of the bilayer. Broadly, at a given temperature a lipidbilayer can exist in either a liquid or a solid phase. The solid phase is commonly...
The lipidbilayer (or phospholipid bilayer) is a thin polar membrane made of two layers of lipid molecules. These membranes are flat sheets that form a...
packed than the surrounding bilayer, but float freely within the membrane bilayer. Although more common in the cell membrane, lipid rafts have also been reported...
functional cell membranes. According to this biological model, there is a lipidbilayer (two molecules thick layer consisting primarily of amphipathic phospholipids)...
fluidity refers to the viscosity of the lipidbilayer of a cell membrane or a synthetic lipid membrane. Lipid packing can influence the fluidity of the...
spheres of lipid molecules (micelles), pairs of layers that face one another (lamellar phase, observed in biological systems as a lipidbilayer), a tubular...
Lipidbilayer characterization is the use of various optical, chemical and physical probing methods to study the properties of lipidbilayers. Many of...
and shapes of lamellar, micellar and hexagonal phases of lipidbilayerphasebehavior and mixed lipid polymorphism in aqueous dispersions can be easily...
polymorphism of amphiphile (lipid) behavior. Phasebehavior is an area of study within biophysics. Micelles and bilayers form in the polar medium by a...
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value.[citation needed] Phase transitions play many important roles in biological systems. Examples include the lipidbilayer formation, the coil-globule...
space). The cell membrane consists of a lipidbilayer, made up of two layers of phospholipids with cholesterols (a lipid component) interspersed between them...
theory is an effective tool for modeling liquid crystal devices and lipidbilayers. Scientists and engineers are able to use liquid crystals in a variety...
integral membrane proteins, or penetrate the peripheral regions of the lipidbilayer. The regulatory protein subunits of many ion channels and transmembrane...
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drug delivery method that involves the use of liposomes (artificial lipidbilayer vesicles) coupled with monoclonal antibodies to deliver therapeutic...
biomolecular condensates—similar in importance to compartmentalisation via lipidbilayer membranes, a type of liquid crystal. The term biomolecular condensate...
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by slowing the chain reaction due to isotope effect on lipid peroxidation. The lipidbilayer of the cell and organelle membranes contain polyunsaturated...
of lipids and cholesterol. They semiquantitatively reproduce the phasebehavior of bilayers with other bilayer properties, and more complex bilayer behavior...
enclosed by a lipid monolayer. The formation of these structures involves phase separation to from colloidal micelles or liquid crystal bilayers, but they...
properties of bilayer graphene. One way to synthesize bilayer graphene is via chemical vapor deposition, which can produce large bilayer regions that almost...
attraction of specific protein regions towards the hydrophobic region inside lipidbilayer. The hydrophobic or hydrophilic character of a compound or amino acid...
membrane. Electropores were optically imaged in lipidbilayer models like droplet interface bilayers and giant unilamellar vesicles, while addition of...
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