Polymorphism in biophysics is the ability of lipids to aggregate in a variety of ways, giving rise to structures of different shapes, known as "phases". This can be in the form of spheres of lipid molecules (micelles), pairs of layers that face one another (lamellar phase, observed in biological systems as a lipid bilayer), a tubular arrangement (hexagonal), or various cubic phases (Fd3m, Im3m, Ia3m, Pn3m, and Pm3m being those discovered so far). More complicated aggregations have also been observed, such as rhombohedral, tetragonal and orthorhombic phases.
It forms an important part of current academic research in the fields of membrane biophysics (polymorphism), biochemistry (biological impact) and organic chemistry (synthesis).
Determination of the topology of a lipid system is possible by a number of methods, the most reliable of which is x-ray diffraction. This uses a beam of x-rays that are scattered by the sample, giving a diffraction pattern as a set of rings. The ratio of the distances of these rings from the central point indicates which phase(s) are present.
The structural phase of the aggregation is influenced by the ratio of lipids present, temperature, hydration, pressure and ionic strength (and type).
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Polymorphism in biophysics is the ability of lipids to aggregate in a variety of ways, giving rise to structures of different shapes, known as "phases"...
Look up polymorphism, polymorph, polymorphic, polymorphous, or polymorphy in Wiktionary, the free dictionary. Polymorphism, polymorphic, polymorph, polymorphous...
areas of research in chemistry and biochemistry, notably that of lipidpolymorphism. Organic compounds containing hydrophilic groups at both ends of the...
The lipid bilayer (or phospholipid bilayer) is a thin polar membrane made of two layers of lipid molecules. These membranes are flat sheets that form a...
Other aggregations are also observed and form part of the polymorphism of amphiphile (lipid) behavior. Phase behavior is an area of study within biophysics...
culture media products, and has also been used in extensive studies of lipidpolymorphism because this organism alters its ratio of MGlcDG (monoglucosyl diacylglycerol)...
now been superseded, as through the study of lipidpolymorphism it is now known that the behaviour of lipids under physiological (and other) conditions...
membrane surface, yet the membrane is flexible. These lipids vary in shape (see page on lipidpolymorphism). The constituent molecules can inter-mingle easily...
of lamellar, micellar and hexagonal phases of lipid bilayer phase behavior and mixed lipidpolymorphism in aqueous dispersions can be easily identified...
theory LipidpolymorphismLipid bilayer Micelle Unilamellar liposome YashRoy R C (1990) Magnetic resonance studies of dynamic organisation of lipids in chloroplast...
localization in the plasma membrane, study ion channels, etc. Lipidpolymorphism Liposome Lipid bilayer Rideau E, Dimova R, Schwille P, Wurm FR, Landfester...
Steinmetz A (January 1979). "Polymorphism of apolipoprotein E. III. Effect of a single polymorphic gene locus on plasma lipid levels in man". Clinical Genetics...
prevent cardiovascular disease in those at high risk and to treat abnormal lipid levels. For the prevention of cardiovascular disease, statins are a first-line...
micellisation and forms part of the phase behaviour of many lipids according to their polymorphism. The ability of a soapy solution to act as a detergent has...
common amino acid polymorphism in the cholesteryl ester transfer protein in men with and without hypertriglyceridemia". Journal of Lipid Research. 39 (5):...
Hyperlipidemia is abnormally high levels of any or all lipids (e.g. fats, triglycerides, cholesterol, phospholipids) or lipoproteins in the blood. The...
protobiont) is a self-organized, endogenously ordered, spherical collection of lipids proposed as a rudimentary precursor to cells during the origin of life....
1039/f29767201525. Cullis, Pieter (1986). "LipidPolymorphism and the Roles of Lipids in Membranes". Chemistry and Physics of Lipids. 40 (2–4): 127–144. doi:10...
The same group of atoms can often solidify in many different ways. Polymorphism is the ability of a solid to exist in more than one crystal form. For...
Lipid profile Lipids Vertical auto profile Hypertriglyceridemia, the presence of high amounts of triglycerides in the blood. "Nomenclature of Lipids"...
gene. As the major component of HDL particles, it has a specific role in lipid metabolism. APOA1 is located on chromosome 11, with its specific location...
proteins that bind lipids (oil-soluble substances such as fats, cholesterol and fat soluble vitamins) to form lipoproteins. They transport lipids in blood, cerebrospinal...
et al. (1995). "Apolipoprotein A-IV polymorphism in the Hungarian population: gene frequencies, effect on lipid levels, and sequence of two new variants"...
do not, particularly Halobates. Water striders experience wing length polymorphism that has affected their flight ability and evolved in a phylogenetic...