Granulation tissue with a poorly formed granuloma to the left of centre. Within this area there is a multinucleate giant cell of the Langhans type. The patient had a healing mycobacterial infection of the skin (Mycobacterium ulcerans infection).
Langhans giant cells (LGC) are giant cells found in granulomatous conditions.
They are formed by the fusion of epithelioid cells (macrophages), and contain nuclei arranged in a horseshoe-shaped pattern in the cell periphery.[1]
Although traditionally their presence was associated with tuberculosis, they are not specific for tuberculosis or even for mycobacterial disease. In fact, they are found in nearly every form of granulomatous disease, regardless of etiology.
^"Pulmonary Pathology". Retrieved 2008-11-21.
and 19 Related for: Langhans giant cell information
granulomatous disease, regardless of etiology. Langhansgiantcells are named after Theodor Langhans (1839–1915), a German pathologist. In 2012, a research...
diseases. Langhansgiantcell could be closely related to tuberculosis, syphilis, sarcoidosis, and deep fungal infections. Langhansgiantcell occurs frequently...
mistakenly identified the cells as part of the nervous system. Langhansgiantcell List of distinct cell types in the adult human body Masci, Anna; Arighi, Cecilia...
another, forming aggregates known as giantcells. When examined by transmission electron microscopy in epithelioid cells in the field of Golgi lamellar complex...
pathology, Schaumann bodies are calcium and protein inclusions inside of Langhansgiantcells as part of a granuloma. Many conditions can cause Schaumann bodies...
using a canine model of induced nephritis. Langhans is remembered for his discovery of multi-nucleated giantcells that are found in granulomatous conditions...
("non-caseating") granulomas in various organs and tissues. Giantcells, specifically Langhansgiantcells, are often seen in sarcoidosis. Schaumann bodies seen...
Kupffer cells – Karl Wilhelm von Kupffer Langer's lines – Karl Langer Islets of Langerhans and Langerhans cell – Paul Langerhans Langhansgiantcell – Theodor...
to both the inner layer of the trophoblast (also called layer of Langhans) or the cells that live there. It is interior to the syncytiotrophoblast and external...
(January 2012). "The CD40-CD40L axis and IFN-γ play critical roles in Langhansgiantcell formation". International Immunology. 24 (1): 5–15. doi:10.1093/intimm/dxr088...
marks. Histologically, it shows presence of epithelioid cell granulomas with Langhansgiantcells with or without central caseation necrosis in the dermis...
tuberculosis is characterized in tissue by caseating granulomas containing Langhansgiantcells, which have a "horseshoe" pattern of nuclei. M. tuberculosis can...
tubercule). This consists of giant multinucleated cells and (Langhanscells), surrounded by epithelioid cells aggregates, T cell lymphocytes and fibroblasts...
and scabies, Nihon Kohshuuhokenkyoukai Zasshi, 10,11,1934 On the Langhansgiantcell in leprosy and the stellate body in nodular leprosy, Int J Lepr 3...
gamma-glutamyltransferase, urea and creatinine levels remain normal. Langhans type multinucleate giantcells may be present in the lymph nodes and the choroid plexus...
Grönwall. On May 3, Draconian announced the departure of singer Heike Langhans and the return of Lisa Johansson on vocals, as well as the addition of...
by P. curvatum is characterized by the presence of a number of Langhan-type giantcells, fibroblasts, macrophages surrounded by lymphocytes, as well as...
Global Information