Aggregation of macrophages in response to chronic inflammation
"Granulomatous" and "Granulomatous reactions" redirect here. For the Interstitial granulomatous drug reaction, see Interstitial granulomatous drug reaction.
Not to be confused with Granulation tissue.
Medical condition
Granuloma
Picture of a granuloma (without necrosis) as seen through a microscope on a glass slide: The tissue on the slide is stained with two standard dyes (hematoxylin: blue, eosin: pink) to make it visible. The granuloma in this picture was found in a lymph node of a patient with a Mycobacterium avium infection.
Specialty
Pathology
A granuloma is an aggregation of macrophages (along with other cells) that forms in response to chronic inflammation. This occurs when the immune system attempts to isolate foreign substances that it is otherwise unable to eliminate.[1] Such substances include infectious organisms including bacteria and fungi, as well as other materials such as foreign objects, keratin, and suture fragments.[2][3][4][5]
^Williams O, Fatima S (5 April 2020). "Granuloma". StatPearls. Treasure Island: StatPearls Publishing. PMID 32119473. Archived from the original on 23 May 2021. Retrieved 2 December 2020.
^Cite error: The named reference Muk7 was invoked but never defined (see the help page).
^Woodard BH, Rosenberg SI, Farnham R, Adams DO (1982). "Incidence and nature of primary granulomatous inflammation in surgically removed material". American Journal of Surgical Pathology. 6 (2): 119–129. doi:10.1097/00000478-198203000-00004. PMID 7102892. S2CID 12907076.
^Hunter DC, Logie JR (1988). "Suture granuloma". British Journal of Surgery. 75 (11): 1149–1150. doi:10.1002/bjs.1800751140. PMID 3208057. S2CID 12804852.
^Chen KT, Kostich ND, Rosai J (1978). "Peritoneal foreign body granulomas to keratin in uterine adenocanthoma". Archives of Pathology and Laboratory Medicine. 102 (4): 174–177. PMID 580709.
the term granuloma are the lesions known as vocal cord granuloma (known as contact granuloma), pyogenic granuloma, and intubation granuloma, all of which...
A pyogenic granuloma or lobular capillary hemangioma is a vascular tumor that occurs on both mucosa and skin, and appears as an overgrowth of tissue due...
A sperm granuloma is a lump of leaked sperm that appears along the vasa deferentia or epididymides in vasectomized individuals. While the majority of...
Granuloma annulare (GA) is a common, sometimes chronic skin condition which presents as reddish bumps on the skin arranged in a circle or ring. It can...
A lick granuloma, also known as acral lick dermatitis, is a skin disorder found most commonly in dogs, but also in cats. In dogs, it results typically...
It is also known as donovanosis, granuloma genitoinguinale, granuloma inguinale tropicum, granuloma venereum, granuloma venereum genitoinguinale, lupoid...
Aquarium granuloma (also known as fish tank granuloma and swimming pool granuloma) is a rare skin condition caused by a non-tubercular mycobacterium known...
Periapical granuloma, also sometimes referred to as a radicular granuloma or apical granuloma, is an inflammation at the tip of a dead (nonvital) tooth...
Contact granuloma is a condition that develops due to persistent tissue irritation in the posterior larynx. Benign granulomas, not to be confused with...
Granuloma faciale is an uncommon benign chronic skin disease of unknown origin characterized by single or multiple cutaneous nodules, usually occurring...
Human eosinophilic granuloma is characterized by abnormal proliferation of Langerhans cells (LCs). LCs are antigen-presenting cells derived from dendritic...
Intubation granuloma is a benign growth of granulation tissue in the larynx or trachea, which arises from tissue trauma due to endotracheal intubation...
Umbilical granuloma is the most common umbilical abnormality in newborn children or neonates, causing inflammation and drainage. It may appear in the...
and range from rashes and noduli (small bumps) to erythema nodosum, granuloma annulare, or lupus pernio. Sarcoidosis and cancer may mimic one another...
Silicone granulomas are a skin condition that occur as a reaction to liquid silicones, and are characterized by the formation of nodules.: 46 Formation...
Actinic granuloma (AG) was first described by O'Brien in 1975 as a rare granulomatous disease. Lesions appear on sun-exposed areas, usually on the face...
A fibrin ring granuloma, also known as doughnut granuloma, is a histopathological finding that is characteristic of Q fever. On hematoxylin-eosin staining...
Granuloma multiforme is a cutaneous condition most commonly seen in central Africa, and rarely elsewhere, characterized by skin lesions that are on the...
Zirconium granulomas are a skin condition characterized by a papular eruption involving the axillae, and are sometimes considered an allergic reaction...
Interstitial lung disease (ILD), or diffuse parenchymal lung disease (DPLD), is a group of respiratory diseases affecting the interstitium (the tissue)...
Generalized granuloma annulare is a skin condition of unknown cause, tending to affect women in the fifth and sixth decades, presenting as a diffuse but...
Beryllium granulomas is a skin condition caused by granulomatous inflammation of the skin which may follow accident laceration, usually in the occupational...
Subcutaneous granuloma annulare is a skin condition of unknown cause, most commonly affecting children, with girls affected twice as commonly as boys...
Localized granuloma annulare is a skin condition of unknown cause, tending to affect children and young to middle-aged adults, usually appearing on the...
Plasma cell granulomas (PCGs) are uncommon, non-neoplastic lesions of unknown etiology and are considered an entity of IgG4-related diseases. PCGs were...
Mercury granulomas is the result of mercury exposure, a skin condition characterized by foreign-body giant cell reaction.: 46 Granuloma Skin lesion James...
Global Information