Albumin infusion in hepatic resection (>40%), nephrotic syndrome (with diuretics and corticosteroids), spontaneous bacterial peritonitis (with antibiotics), and hepatorenal syndrome (with terlipressin)
Frequency
70% (elderly inpatients)
Hypoalbuminemia (or hypoalbuminaemia) is a medical sign in which the level of albumin in the blood is low.[1] This can be due to decreased production in the liver, increased loss in the gastrointestinal tract or kidneys, increased use in the body, or abnormal distribution between body compartments. Patients often present with hypoalbuminemia as a result of another disease process such as malnutrition as a result of severe anorexia nervosa, sepsis, cirrhosis in the liver, nephrotic syndrome in the kidneys, or protein-losing enteropathy in the gastrointestinal tract. One of the roles of albumin is being the major driver of oncotic pressure (protein concentration within the blood) in the bloodstream and the body. Thus, hypoalbuminemia leads to abnormal distributions of fluids within the body and its compartments. As a result, associated symptoms include edema in the lower legs, ascites in the abdomen, and effusions around internal organs. Laboratory tests aimed at assessing liver function diagnose hypoalbuminemia. Once identified, it is a poor prognostic indicator for patients with a variety of different diseases. Yet, it is only treated in very specific indications in patients with cirrhosis and nephrotic syndrome. Treatment instead focuses on the underlying cause of the hypoalbuminemia. Albumin is an acute negative phase respondent and not a reliable indicator of nutrition status.
^Anderson, Douglas M. (2000). Dorland's illustrated medical dictionary (29. ed.). Philadelphia [u.a.]: Saunders. p. 860. ISBN 0721682618.
Hypoalbuminemia (or hypoalbuminaemia) is a medical sign in which the level of albumin in the blood is low. This can be due to decreased production in...
concentration. Decreased colloidal osmotic pressure, most notably seen in hypoalbuminemia, can cause edema and decrease in blood volume as fluid is not reabsorbed...
years of age, the normal range is broader, 2.9–5.5 g/dL. Low albumin (hypoalbuminemia) may be caused by liver disease, nephrotic syndrome, burns, protein-losing...
tubular acidosis, spironolactone. A low anion gap is often due to hypoalbuminemia. Albumin is an anionic protein and its loss results in the retention...
> 40 mg per square meter body surface area per hour in children), hypoalbuminemia (< 3.5 g/dl), hyperlipidaemia, and edema that begins in the face. Lipiduria...
kwashiorkor. They include, but are not limited to protein deficiency causing hypoalbuminemia, amino acid deficiency, oxidative stress, and gut microbiome changes...
leads to hypoalbuminemia and decreasing of colloid oncotic pressure in plasma that causes edema) Nephrotic syndrome (also due to hypoalbuminemia caused...
combination with adequate rehydration. In chronic kidney diseases with hypoalbuminemia, furosemide is used along with albumin to increase diuresis. It is...
factors Female sex, obesity, use of Warfarin, protein C or S deficiency, hypoalbuminemia, diabetes mellitus, use of vitamin D derivatives (calcitriol, systemic...
(low blood pressure), hemoconcentration (thickening of the blood) and hypoalbuminemia (drop in albumin, a major protein) in the absence of other causes for...
to adjust serum total calcium concentration upward or downward if hypoalbuminemia or hyperalbuminemia is present, respectively (measured serum total...
present with early-onset gastrointestinal symptoms, edema, malnutrition, hypoalbuminemia, and hypogammaglobulinemia. Histopathological assessment of intestinal...
"Ascites in cirrhosis: Relative importance of portal hypertension and hypoalbuminemia". The American Journal of Digestive Diseases. 12 (9): 916–922. doi:10...
implications in patients with low blood protein levels (hypoproteinemia/hypoalbuminemia) and in patients that are on concurrent therapies that are also highly...
Colistin-induced nephrotoxicity is particularly likely in patients with hypoalbuminemia. The main toxicity described with aerosolised treatment is bronchospasm...
include antibiotic or proton pump inhibitor use, hospitalization, hypoalbuminemia, other health problems, and older age. Diagnosis is by stool culture...
Vasovagal Syncope or POTS Postural Orthostatic Tachycardia Syndrome Hypoalbuminemia Loss of blood (external or internal bleeding or blood donation) The...
deficiency massive haemorrhage C1 inhibitor hereditary angioedema albumin hypoalbuminemia Ascites Restoring of blood volume in trauma, burns and surgery patients...
cells in the stomach also causing excess protein loss, leading to hypoalbuminemia (presents with abdominal pain and edema). Prevalence Achlorhydria is...
soft tissues as a consequence of water retention), weight gain, and hypoalbuminemia (low serum albumin). These signs are referred to collectively as nephrotic...
g/L See serum total protein Interpretation Albumin 35 48, 55 g/L See hypoalbuminemia 3.5 4.8, 5.5 U/L 540 740 μmol/L Globulins 23 35 g/L Total bilirubin...
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