The Human Protein Atlas portal is a publicly available database with millions of high-resolution images showing the spatial distribution of proteins in normal human tissues and different cancer types, as well the sub cellular localisation in single cells.
Organisms
Human
Contact
Research center
KTH, UU, SciLifeLab, Sweden
Primary citation
Uhlén M, et al. (January 2015). "Proteomics. Tissue-based map of the human proteome". Science. 347 (6220): 1260419. doi:10.1126/science.1260419. PMID 25613900. S2CID 802377.
Access
Website
www.proteinatlas.org
Download URL
www.proteinatlas.org/about/download
Tools
Web
Advanced search, bulk retrieval/download
Miscellaneous
Versioning
Yes
Data release frequency
12 months
Version
23
Curation policy
Yes – manual
Bookmarkable entities
Yes – both individual protein entries and searches
The Human Protein Atlas (HPA) is a Swedish-based program started in 2003 with the aim to map all the human proteins in cells, tissues and organs using integration of various omics technologies, including antibody-based imaging, mass spectrometry-based proteomics, transcriptomics and systems biology. All the data in the knowledge resource is open access to allow scientists both in academia and industry to freely access the data for exploration of the human proteome. In June 2023, version 23 was launched where a new Interaction section was introduced containing human protein-protein interaction networks for more than 11,000 genes that will add new aspects in terms of protein function.
The resource now includes twelve separate sections with complementary information about all human proteins. All data has been updated on the approximately 5 million individual web pages. The Human Protein Atlas program has already contributed to several thousands of publications in the field of human biology and disease and was selected by the organization ELIXIR as a European core resource due to its fundamental importance for a wider life science community. The HPA consortium is funded by the Knut and Alice Wallenberg Foundation.
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are provided. HumanProteinAtlas (HPA): a public database with expression profiles of humanprotein coding genes both on mRNA and protein level in tissues...
of the organism, and the synthesis of proteins and biochemicals necessary for digestion and growth. In humans, it is located in the right upper quadrant...
of these proteins that allows us to observe cell types is the Swedish ProteinAtlas. The Human Brain Project has attempted to map the human brain, although...
TCP-seq Glycomics HumanProteinAtlasHumanProtein Reference Database National Center for Biotechnology Information (NCBI) PeptideAtlasProtein Data Bank (PDB)...
1186/s40168-017-0268-4. PMC 5410102. PMID 28454555. "The human proteome in endometrium - The HumanProteinAtlas". www.proteinatlas.org. Retrieved 2017-09-25. Uhlén...
Livingstone. pp. 295–299. ISBN 978-0-8089-2306-0. "The human proteome in small intestine - The HumanProteinAtlas". www.proteinatlas.org. Retrieved 2017-09-26...
1148/radiol.12112469. ISSN 0033-8419. PMID 23264525. "The human proteome in duodenum - The HumanProteinAtlas". www.proteinatlas.org. Retrieved 2017-09-26. Uhlén...
1354–63. doi:10.1002/ar.22950. PMID 24903594. "The human proteome in salivary gland - The HumanProteinAtlas". www.proteinatlas.org. Retrieved 2017-09-22....
were enrolled in the Collaborative Project. "The human proteome in placenta - The HumanProteinAtlas". www.proteinatlas.org. Archived from the original...
in the adult human body ENCODE - Encyclopedia of DNA Elements (ENCODE) Human Genome Project HumanProteinAtlasHuman Biomolecular Atlas Program Preidt...
stomach in Wiktionary, the free dictionary. Stomach at the HumanProteinAtlas Digestion of proteins in the stomach or tiyan (archived 10 March 2007) Site...
Claypool Life Sciences. ISBN 9781615041503. "The human proteome in gastrointestinal tract - The HumanProteinAtlas". www.proteinatlas.org. Retrieved 2017-09-21...
webpath.med.utah.edu. Retrieved 2019-11-17. "The human proteome in prostate – The HumanProteinAtlas". www.proteinatlas.org. Retrieved 2017-09-26. Uhlén...
PMC 8893647. PMID 35180215. "The human cell in cytoplasm". HumanProteinAtlas. "Nuclear Membrane". National Human Genome Research Institute. Pederson...
Microarrays, Immunohistochemistry Staining and Digitalization Within the HumanProteinAtlas". Journal of Visualized Experiments (63): e3620. doi:10.3791/3620...
colour atlas (6th ed.). Philadelphia: Elsevier. ISBN 9780702047473. Media related to Pancreas at Wikimedia Commons Pancreas at the HumanProteinAtlas Pancreatic...
92.8% of the predicted proteins coded in the human genome. BioPlex HumanProteinAtlas - Protein databases NeXtProt PeptideAtlas Legrain, P.; Aebersold...
rock band The Hives Hectopascal (hPa), a unit of pressure Human platelet antigen HumanProteinAtlas Hydrogen pinch analysis Hypothalamic–pituitary–adrenal...
original on 23 August 2018. Retrieved 31 July 2016. "The human proteome in heart – The HumanProteinAtlas". www.proteinatlas.org. Archived from the original...
role for lungs in blood formation". 2017-04-03. "The human proteome in lung – The HumanProteinAtlas". www.proteinatlas.org. Retrieved 2017-09-25. Uhlén...
Testis-expressed protein 9 is a protein that in humans is encoded the TEX9 gene. TEX9 that encodes a 391-long amino acid protein containing two coiled-coil...
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Taylor & Francis. pp. 35–44. ISBN 9780429163470. "The human proteome in skin – The HumanProteinAtlas". www.proteinatlas.org. Uhlén M, Fagerberg L, Hallström...
Zinc finger protein 684 is a protein that in humans is encoded by the ZNF684 gene. The zinc finger protein 684 is also known as the Kruppel-associated...
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