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Guide to Pharmacology information


IUPHAR/BPS Guide to PHARMACOLOGY
Content
DescriptionAn online, open-access portal to pharmacological information on all the human targets of prescription drugs
Data types
captured
Target nomenclature, pharmacological data, ligand structures
OrganismsHuman, Mouse, Rat
Contact
Research centreUniversity of Edinburgh, UK
Primary citationThe IUPHAR/BPS Guide to PHARMACOLOGY in 2020: extending immunopharmacology content and introducing the IUPHAR/MMV Guide to MALARIA PHARMACOLOGY [1]
Access
Websitewww.guidetopharmacology.org
Web service URLwww.guidetopharmacology.org/webServices.jsp
Sparql endpointrdf.guidetopharmacology.org/sparql
Miscellaneous
VersioningContent updated approx quarterly (i.e. 2020.2 indicates [year].[release number])
Curation policyManual, in-house

The IUPHAR/BPS Guide to PHARMACOLOGY is an open-access website, acting as a portal to information on the biological targets of licensed drugs and other small molecules. The Guide to PHARMACOLOGY (with GtoPdb being the standard abbreviation) is developed as a joint venture between the International Union of Basic and Clinical Pharmacology (IUPHAR) and the British Pharmacological Society (BPS). This replaces and expands upon the original 2009 IUPHAR Database (standard abbreviation IUPHAR-DB). The Guide to PHARMACOLOGY aims to provide a concise overview of all pharmacological targets, accessible to all members of the scientific and clinical communities and the interested public, with links to details on a selected set of targets. The information featured includes pharmacological data, target, and gene nomenclature, as well as curated chemical information for ligands. Overviews and commentaries on each target family are included, with links to key references.

  1. ^ Armstrong, JF; Faccenda, E; Harding, SD; Pawson, AJ; Southan, C; Sharman, JL; Campo, B; Cavanagh, DR; Alexander, SPH; Davenport, AP; Spedding, M; Davies, JA (8 January 2020). "The IUPHAR/BPS Guide to PHARMACOLOGY in 2020: extending immunopharmacology content and introducing the IUPHAR/MMV Guide to MALARIA PHARMACOLOGY". Nucleic Acids Research. 48 (D1): D1006–D1021. doi:10.1093/nar/gkz951. PMC 7145572. PMID 31691834.

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Guide to Pharmacology

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The IUPHAR/BPS Guide to PHARMACOLOGY is an open-access website, acting as a portal to information on the biological targets of licensed drugs and other...

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Pharmacology

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Pharmacology is the science of drugs and medications, including a substance's origin, composition, pharmacokinetics, pharmacodynamics, therapeutic use...

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British Journal of Pharmacology

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correspondence in all fields of pharmacology. It also publishes themed issues, as well as supplements. The Concise Guide to PHARMACOLOGY is a supplement of the...

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International Union of Basic and Clinical Pharmacology

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Clinical Pharmacology (IUPHAR) is a voluntary, non-profit association representing the interests of scientists in pharmacology-related fields to facilitate...

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Opioid peptide

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ability to make and release morphine "μ receptor". IUPHAR/BPS Guide to PHARMACOLOGY. International Union of Basic and Clinical Pharmacology. 15 March...

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Promethazine

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September 2023. "promazine | Ligand Activity Charts | IUPHAR/BPS Guide to PHARMACOLOGY". www.guidetopharmacology.org. Retrieved 18 May 2023. Möller HJ...

Word Count : 2681

Acamprosate

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activity". IUPHAR/BPS Guide to Pharmacology. International Union of Basic and Clinical Pharmacology. Retrieved 26 November 2017. Due to the complex nature...

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Phenylalanine

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2007-06-19. "D-Phenylalanine: Biological activity". The IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved 27 December 2018. Wood DR, Reimherr FW, Wender PH (1985)...

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Orphan receptor

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Biochemical Pharmacology. 153: 62–74. doi:10.1016/j.bcp.2018.02.016. PMID 29454621. S2CID 3566341. "Class A Orphans GPCRs". IUPHAR/BPS Guide to PHARMACOLOGY Database...

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Nicotine

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data". IUPHAR/BPS Guide to Pharmacology. International Union of Basic and Clinical Pharmacology. Retrieved 29 June 2024. Used as an aid to smoking cessation...

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Prostaglandin receptor

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- IUPHAR/BPS Guide to PHARMACOLOGY". www.guidetopharmacology.org. "DP2 receptor - Prostanoid receptors - IUPHAR/BPS Guide to PHARMACOLOGY". www.guidetopharmacology...

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Naloxone

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2018. "Naloxone: Summary". IUPHAR/BPS Guide to Pharmacology. International Union of Basic and Clinical Pharmacology. Archived from the original on 16 November...

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Butyric acid

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"Hydroxycarboxylic acid receptors". IUPHAR/BPS Guide to Pharmacology. International Union of Basic and Clinical Pharmacology. Retrieved 13 July 2018. Carroll, Mark...

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Fluoxetine

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doi:10.2174/1871524910909030197. PMID 20021354. "Fluoxetine". IUPHAR Guide to Pharmacology. IUPHAR. Archived from the original on 10 November 2014. Retrieved...

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Antihistamine

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01314.x. PMID 11972592. S2CID 11849647. "H1 receptor". IUPHAR/BPS Guide to Pharmacology. Retrieved 8 October 2015. Norrby K (1995). "Evidence of a dual...

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Prazosin

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Basic and Clinical Pharmacology. Retrieved 3 June 2016. "Prazosin". DrugBank. "Prazosin Ligand page". IUPHAR/BPS Guide to PHARMACOLOGY. "Prazosin: Clinical...

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Lactic acid

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"Hydroxycarboxylic acid receptors". IUPHAR/BPS Guide to Pharmacology. International Union of Basic and Clinical Pharmacology. Retrieved 13 July 2018. Badet C, Thebaud...

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Tetrodotoxin

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PMID 30049784. "Tetrodotoxin | Ligand page | IUPHAR/BPS Guide to Pharmacology". Guide to Pharmacology. International Union of Pharmacologists. Narahashi T...

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Endorphins

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ability to make and release morphine "μ receptor". IUPHAR/BPS Guide to PHARMACOLOGY. International Union of Basic and Clinical Pharmacology. 15 March...

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Melatonin

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"Melatonin receptors | G protein-coupled receptors | IUPHAR/BPS Guide to Pharmacology". www.guidetopharmacology.org. Retrieved 7 April 2017. Sharafati-Chaleshtori...

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Quantitative systems pharmacology

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research & development to help guide the discovery and development of new therapies. QSP has been used by the FDA in a clinical pharmacology review. QSP emerged...

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Adrenaline

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ISBN 0-7167-4339-6. "SLC18 family of vesicular amine transporters". Guide to Pharmacology. IUPHAR/BPS. Retrieved 21 August 2015. Oanca G, Stare J, Mavri J...

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Clinical pharmacology

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The Hands-on Guide to Clinical Pharmacology. 3rd ed., Wiley-Blackwell, 2010 Katzung, Bertram G. (2010). Basic & Clinical Pharmacology. San Francisco...

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List of chemical databases

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Sanford, Adam (13 May 2022). "CAS Common Chemistry in 2021: Expanding Access to Trusted Chemical Information for the Scientific Community". Journal of Chemical...

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Triethylamine

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Retrieved 2020-06-17. "tetraethylammonium | Ligand page | IUPHAR/BPS Guide to PHARMACOLOGY". www.guidetopharmacology.org. Retrieved 2020-06-17. Eller, Karsten;...

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Dopamine

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"Dopamine: Biological activity". IUPHAR/BPS guide to pharmacology. International Union of Basic and Clinical Pharmacology. Retrieved 29 January 2016. Berridge...

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Histamine

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November 2016). "H2 receptor". IUPHAR/BPS Guide to Pharmacology. International Union of Basic and Clinical Pharmacology. Archived from the original on 21 March...

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Adrenergic receptor

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illustrated The Adrenergic Receptors Adrenoceptors - IUPHAR/BPS guide to pharmacology Basic Neurochemistry: α- and β-Adrenergic Receptors Theory of receptor...

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