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Globulin information


The globulins are a family of globular proteins that have higher molecular weights than albumins and are insoluble in pure water but dissolve in dilute salt solutions. Some globulins are produced in the liver, while others are made by the immune system. Globulins, albumins, and fibrinogen are the major blood proteins. The normal concentration of globulins in human blood is about 2.6-3.5 g/dL.

The term "globulin" is sometimes used synonymously with "globular protein". However, albumins are also globular proteins, but are not globulins. All other serum globular proteins are globulins.

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Globulin

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main sections for globulin would be the alpha globulins, beta globulin, and gamma globulin. The alpha globulins and the beta globulin are mainly created...

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Gamma globulin

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Gamma globulins are a class of globulins, identified by their position after serum protein electrophoresis. The most significant gamma globulins are immunoglobulins...

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Alpha globulin

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Alpha globulins are a group of globular proteins in plasma that are highly mobile in alkaline or electrically charged solutions. They inhibit certain...

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Beta globulin

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than alpha globulins. Examples of beta globulins include: beta-2 microglobulin plasminogen angiostatins properdin sex hormone-binding globulin transferrin...

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Coombs test

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antibodies from the red blood cells) and then incubated with anti-human globulin ("Coombs reagent"). If the red cells then agglutinate, the test is positive...

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Immunoglobulin therapy

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include: Alyglo (immune globulin intravenous human-stwk) Asceniv (immune globulin intravenous, human – slra) Bivigam (immune globulin intravenous – human...

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Transcortin

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globulin (CBG) or serpin A6, is a protein produced in the liver in animals. In humans it is encoded by the SERPINA6 gene. It is an alpha-globulin. This...

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Haemophilia

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Patek and Taylor, two doctors from Harvard, discovered anti-haemophilic globulin. In 1947, Alfredo Pavlovsky, a doctor from Buenos Aires, found haemophilia...

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VZV immune globulin

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varicella zoster virus globulin (VZV globulin), VZV antibodies, zoster immunoglobulin (ZIG), varicella zoster immune globulin (VZIG or VARIZIG), is an...

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Hyaluronidase

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with one vial of immune globulin infusion 10% (human) and one vial of recombinant human hyaluronidase. It is an immune globulin with a recombinant human...

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Hepatitis B immune globulin

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globulin Use During Pregnancy". Drugs.com. 3 August 2020. Retrieved 13 September 2020. Zuckerman JN (July 2007). "Review: hepatitis B immune globulin...

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Anthrax immune globulin

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Anthrax immune globulin, tradename Anthrasil, is a human immune globulin that is used in combination with antibiotics to treat anthrax. It was developed...

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Blood plasma

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and contains important dissolved proteins (6–8%; e.g., serum albumins, globulins, and fibrinogen), glucose, clotting factors, electrolytes (Na+ , Ca2+...

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Rabies immunoglobulin

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rabies virus immune globulin injection, solution". DailyMed. Retrieved 24 March 2020. "Kedrab- human rabies virus immune globulin injection, solution"...

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Vaccinia immune globulin

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Vaccinia immune globulin (VIG) is made from the pooled blood of individuals who have been inoculated with the smallpox vaccine. The antibodies these individuals...

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Fibronectin

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vertebrates: soluble plasma fibronectin (formerly called "cold-insoluble globulin", or CIg) is a major protein component of blood plasma (300 μg/ml) and...

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Rh disease

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immune globulin (Rhoclone, Rhogam, AntiD). With successful mitigation of this disease by prevention through the use of anti-Rho(D) immune globulin, other...

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Thymoglobulin

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off-label uses. Antithymocyte globulin (ATG) was originally developed as one of various tested preparations of antilymphocyte globulin (ALG) specifically generated...

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Monoclonal gammopathy

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the presence of excessive amounts of myeloma protein or monoclonal gamma globulin in the blood. It is usually due to an underlying immunoproliferative disorder...

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Antibody

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proteins, antibodies mostly migrate to the last, gamma globulin fraction. Conversely, most gamma-globulins are antibodies, which is why the two terms were historically...

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11S globulin family

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11S globulin family is a family of globulin proteins chiefly found in seeds of legumes (legumin-like), along with 7S family, often found in a protein...

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Steroid hormone

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specific carrier proteins such as sex hormone-binding globulin or corticosteroid-binding globulin. Further conversions and catabolism occurs in the liver...

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Major urinary proteins

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Major urinary proteins (Mups), also known as α2u-globulins, are a subfamily of proteins found in abundance in the urine and other secretions of many animals...

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