Transcortin, also known as corticosteroid-binding globulin (CBG) or serpin A6, is a protein produced in the liver in animals. In humans it is encoded by the SERPINA6 gene. It is an alpha-globulin.[5][6][7]
^ abcGRCm38: Ensembl release 89: ENSMUSG00000060807 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Hammond GL, Smith CL, Goping IS, Underhill DA, Harley MJ, Reventos J, Musto NA, Gunsalus GL, Bardin CW (August 1987). "Primary structure of human corticosteroid binding globulin, deduced from hepatic and pulmonary cDNAs, exhibits homology with serine protease inhibitors". Proc Natl Acad Sci U S A. 84 (15): 5153–7. Bibcode:1987PNAS...84.5153H. doi:10.1073/pnas.84.15.5153. PMC 298812. PMID 3299377.
^Byth BC, Billingsley GD, Cox DW (July 1994). "Physical and genetic mapping of the serpin gene cluster at 14q32.1: allelic association and a unique haplotype associated with alpha 1-antitrypsin deficiency". Am J Hum Genet. 55 (1): 126–33. PMC 1918218. PMID 7912884.
^"Entrez Gene: SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6".
Transcortin, also known as corticosteroid-binding globulin (CBG) or serpin A6, is a protein produced in the liver in animals. In humans it is encoded...
glucocorticoids and some synthetic corticoids have high affinity to the protein transcortin (also called corticosteroid-binding globulin), whereas all of them bind...
cortisol measurement. Cortisol is lipophilic, and is transported bound to transcortin (also known as corticosteroid-binding globulin (CBG)) and albumin, while...
genealogical and heraldic studies Corticosteroid-binding globulin or transcortin, an alpha 2 globulin (protein) in animals This disambiguation page lists...
endogenous GCs, methylprednisolone does not bind to the glycoprotein transcortin (corticosteroid binding globulin, CBG) but does have moderate protein...
binds extensively to plasma proteins, including albumin (50–54%) and transcortin (43–48%). It has similar affinity for albumin relative to the PR. The...
Glucocorticoids are distributed by binding with protein, mainly glycoprotein, transcortin and albumin. Metabolism The majority of NSAIDs undergo glucoronidation...
(17-BMP) during absorption Protein binding 87% of 17-BMP to albumin and transcortin Metabolism By esterase enzymes found in most tissues Elimination half-life...
glucocorticoid receptors (GRs) and corticosteroid-binding globulin (CBG, or transcortin). GR is a nuclear receptor that inhibits transcription of ACTH via a...
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