Estradiol, an important estrogen steroid hormone in both women and men.
Class identifiers
Synonyms
Adrenal steroid; Gonadal steroid
Use
Various
Biological target
Steroid hormone receptors
Chemical class
Steroidal; Nonsteroidal
Legal status
In Wikidata
A steroid hormone is a steroid that acts as a hormone. Steroid hormones can be grouped into two classes: corticosteroids (typically made in the adrenal cortex, hence cortico-) and sex steroids (typically made in the gonads or placenta). Within those two classes are five types according to the receptors to which they bind: glucocorticoids and mineralocorticoids (both corticosteroids) and androgens, estrogens, and progestogens (sex steroids).[1][2] Vitamin D derivatives are a sixth closely related hormone system with homologous receptors. They have some of the characteristics of true steroids as receptor ligands.
Steroid hormones help control metabolism, inflammation, immune functions, salt and water balance, development of sexual characteristics, and the ability to withstand injury and illness. The term steroid describes both hormones produced by the body and artificially produced medications that duplicate the action for the naturally occurring steroids.[3][4][5]
^"Steroid hormones - Latest research and news | Nature". www.nature.com. Retrieved 2021-12-06.
A steroidhormone is a steroid that acts as a hormone. Steroidhormones can be grouped into two classes: corticosteroids (typically made in the adrenal...
Steroidhormone receptors are found in the nucleus, cytosol, and also on the plasma membrane of target cells. They are generally intracellular receptors...
sex hormones estradiol and testosterone,: 10–19 anabolic steroids, and the anti-inflammatory corticosteroid drug dexamethasone. Hundreds of steroids are...
andr-, the stem of the word meaning "man") is any natural or synthetic steroidhormone that regulates the development and maintenance of male characteristics...
classified as hormones. Among the substances that can be considered hormones, are eicosanoids (e.g. prostaglandins and thromboxanes), steroids (e.g. oestrogen...
a class of steroidhormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones. Two main classes...
testosterone, the main male sex hormone, and produce effects by binding to the androgen receptor. Anabolic steroids have a number of medical uses, but...
and steroidhormones, retinoids and Vitamin D, and a variety of other receptors for various ligands, such as fatty acids and prostaglandins. Hormone receptors...
Progesterone (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other...
cAMP and subsequent activation of protein kinase A. ACTH influences steroidhormone secretion by both rapid short-term mechanisms that take place within...
glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol. They are found above the kidneys...
generous in an ultimatum game. Lipophilic hormones (soluble in lipids but not in water), such as steroidhormones, including testosterone, are transported...
nevertheless have important physiological roles in males. Like all steroidhormones, estrogens readily diffuse across the cell membrane. Once inside the...
including humans. Most hormones can be classified as either amino acid–based hormones (amine, peptide, or protein) or steroidhormones. The former are water-soluble...
steroidogenesis and steroid biosynthesis. They are responsible for the biosynthesis of the steroidhormones, including sex steroids (androgens, estrogens...
levels of estradiol. The hormonal maturation of females is considerably more complicated than in males. The main steroidhormones, testosterone, estradiol...
membrane bound receptor. On the other hand, liposoluble chemicals such as steroidhormones, can diffuse passively across the plasma membrane and interact with...
receptor binds as a dimer. Specifically, HRE responds to steroidhormones, as the activated steroid receptor is the transcription factor binding HRE. This...
types of conditions. Saliva is a useful biological fluid for assaying steroidhormones such as cortisol, genetic material like RNA, proteins such as enzymes...
peptide hormones, as are leptin from adipocytes, ghrelin from the stomach, and insulin from the pancreas.[citation needed] Steroidhormones are converted...
proteins oxidize steroids, fatty acids, and xenobiotics, and are important for the clearance of various compounds, as well as for hormone synthesis and breakdown...
(human chorionic gonadotropin), a hormone very similar to LH but secreted from the new placenta. Gonadal steroids (estrogens and androgens) generally...
pregn-5-en-3β-ol-20-one, is an endogenous steroid and precursor/metabolic intermediate in the biosynthesis of most of the steroidhormones, including the progestogens...
Estrone (E1), also spelled oestrone, is a steroid, a weak estrogen, and a minor female sex hormone. It is one of three major endogenous estrogens, the...
cascades. mSRs are another means besides classical nuclear steroidhormone receptors (SHRs) for steroids to mediate their biological effects. SHRs can produce...
Global Information