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Ginsenoside information


The chemical structure of the ginsenoside Rg1, a member of the dammarane family of molecules.

Ginsenosides or panaxosides are a class of natural product steroid glycosides and triterpene saponins. Compounds in this family are found almost exclusively in the plant genus Panax (ginseng), which has a long history of use in traditional medicine that has led to the study of pharmacological effects of ginseng compounds. As a class, ginsenosides exhibit a large variety of subtle and difficult-to-characterize biological effects when studied in isolation.[1]

Ginsenosides can be isolated from various parts of the plant, though typically from the roots, and can be purified by column chromatography.[2] The chemical profiles of Panax species are distinct; although Asian ginseng, Panax ginseng, has been most widely studied due to its use in traditional Chinese medicine, there are ginsenosides unique to American ginseng (Panax quinquefolius) and Japanese ginseng (Panax japonicus). Ginsenoside content also varies significantly due to environmental effects.[3]

  1. ^ Attele, AS; Wu, JA; Yuan, CS (1 December 1999). "Ginseng pharmacology: multiple constituents and multiple actions". Biochemical Pharmacology. 58 (11): 1685–93. doi:10.1016/s0006-2952(99)00212-9. PMID 10571242.
  2. ^ Fuzzati, N (5 December 2004). "Analysis methods of ginsenosides". Journal of Chromatography B. 812 (1–2): 119–33. doi:10.1016/j.jchromb.2004.07.039. PMID 15556492.
  3. ^ Qi, LW; Wang, CZ; Yuan, CS (June 2011). "Ginsenosides from American ginseng: chemical and pharmacological diversity". Phytochemistry. 72 (8): 689–99. Bibcode:2011PChem..72..689Q. doi:10.1016/j.phytochem.2011.02.012. PMC 3103855. PMID 21396670.

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Ginsenoside

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Ginsenosides or panaxosides are a class of natural product steroid glycosides and triterpene saponins. Compounds in this family are found almost exclusively...

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Ginsenoside Rb1

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Ginsenoside Rb1 (or Ginsenoside Rb1 or GRb1 or GRb1) is a chemical compound belonging to the ginsenoside family. Like other ginsenosides, it is found in...

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Acremonium strictum

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compounds — ginsenoside Rd, gypenoside XVII, ginsenoside Rg, ginsenoside F, and compound K. Many of these compounds are metabolites of ginsenoside Rb(1) in...

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Ginseng

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American ginseng (P. quinquefolius), characterized by the presence of ginsenosides and gintonin. Ginseng is common in the cuisines and medicines of China...

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Sphingomonas kyungheensis

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(October 2013). "Sphingomonas kyungheensis sp. nov., a bacterium with ginsenoside-converting activity isolated from soil of a ginseng field". International...

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Panax notoginseng

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1-3 g. P. notoginseng contains dammarane-type ginsenosides as major constituents. Dammarane-type ginsenosides includes 2 classifications: the 20(S)-protopanaxadiol...

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Neuroprotection

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receptors as well as other glutamate receptors. Ginsenoside Rd: Results from the study show ginsenoside rd attenuates glutamate excitotoxicity. Importantly...

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Mucilaginibacter ginsenosidivorax

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Korea. Mucilaginibacter ginsenosidivorax has the ability to convert ginsenoside. "Mucilaginibacter ginsenosidivorax". www.uniprot.org. Kim, Jin-Kwang;...

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Ketamine

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Diacetylnalorphine Diprenorphine ECG EGC Epicatechin Eptazocine Gemazocine Ginsenoside R Hyperoside Ibogaine JDTic Levallorphan Lobeline LY-255582 LY-2196044...

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Panax

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Araliaceae (ivy) family. Panax species are characterized by the presence of ginsenosides and gintonin. Panax is one of approximately 60 plant genera with a classical...

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Fentanyl

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Oxycodone

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M1

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20-O-beta-D-glucopyranosyl-20(S)-protopanaxadiol, a ppd-type monoglucoside ginsenoside metabolized by intestinal bacteria M1 macrophage, a phenotype of macrophage...

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Furosemide

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(e.g., nicardipine) Etomidate Ginseng constituents (e.g., ginsenosides (e.g., ginsenoside-Rf)) Glutamic acid (glutamate) Ivermectin Ketamine Neuroactive...

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Carfentanil

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Mucilaginibacter composti

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Wan-Taek (30 June 2011). "Mucilaginibacter composti sp. nov., with ginsenoside converting activity, isolated from compost". The Journal of Microbiology...

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Menthol

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Diazepam

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Chloral hydrate

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(e.g., nicardipine) Etomidate Ginseng constituents (e.g., ginsenosides (e.g., ginsenoside-Rf)) Glutamic acid (glutamate) Ivermectin Ketamine Neuroactive...

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RG1

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RG1 may refer to: Ginsenoside Rg1, a bioactive molecule a United Kingdom postcode covering Reading area RG-1 (propellant) is a Russian rocket propellant...

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Caffeine

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Morphine

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Desomorphine

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Pentobarbital

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Phencyclidine

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Glycine

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American ginseng

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contains dammarane-type ginsenosides, or saponins, as the major biologically active constituents. Dammarane-type ginsenosides include two classifications:...

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