Global Information Lookup Global Information

Fumagillin information


Fumagillin
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
  • P01AX10 (WHO) QP51AX23 (WHO)
Identifiers
IUPAC name
  • (2E,4E,6E,8E)-10-{[(3R,4S,5S,6R)-5-methoxy- 4-[(2R)-2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-1- oxaspiro[2.5]octan-6-yl]oxy}-10 -oxodeca-2,4,6,8-tetraenoic acid
CAS Number
  • 23110-15-8 checkY
PubChem CID
  • 6917655
DrugBank
  • DB02640 ☒N
ChemSpider
  • 5292885 ☒N
UNII
  • 7OW73204U1
ChEBI
  • CHEBI:48635 ☒N
ChEMBL
  • ChEMBL32838 ☒N
CompTox Dashboard (EPA)
  • DTXSID7040736 Edit this at Wikidata
ECHA InfoCard100.041.288 Edit this at Wikidata
Chemical and physical data
FormulaC26H34O7
Molar mass458.551 g·mol−1
3D model (JSmol)
  • Interactive image
SMILES
  • CC(=CC[C@@H]1[C@@](O1)(C)[C@H]2[C@@H]([C@@H](CC[C@]23CO3)OC(=O)/C=C/C=C/C=C/C=C/C(=O)O)OC)C
InChI
  • InChI=1S/C26H34O7/c1-18(2)13-14-20-25(3,33-20)24-23(30-4)19(15-16-26(24)17-31-26)32-22(29)12-10-8-6-5-7-9-11-21(27)28/h5-13,19-20,23-24H,14-17H2,1-4H3,(H,27,28)/b7-5+,8-6+,11-9+,12-10+/t19-,20-,23-,24-,25+,26+/m1/s1 ☒N
  • Key:NGGMYCMLYOUNGM-CSDLUJIJSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Fumagillin is a complex biomolecule and used as an antimicrobial agent. It was isolated in 1949 from the microbial organism Aspergillus fumigatus.[1]

  1. ^ F. R. Hanson, T. E. Elbe, J. Bacteriol. 1949, 58, 527

and 30 Related for: Fumagillin information

Request time (Page generated in 0.5384 seconds.)

Fumagillin

Last Update:

Fumagillin is a complex biomolecule and used as an antimicrobial agent. It was isolated in 1949 from the microbial organism Aspergillus fumigatus. It was...

Word Count : 1012

Antifungal

Last Update:

Flucytosine (5-fluorocytosine) – an antimetabolite pyrimidine analog Fumagillin Griseofulvin – binds to microtubules and inhibits mitosis Haloprogin –...

Word Count : 2564

Antiparasitic

Last Update:

infections) Albendazole (broad spectrum) Praziquantel Rifampin Amphotericin B Fumagillin (for microsporidiosis) Antiparasitics treat parasitic diseases, which...

Word Count : 1000

Nosema ceranae

Last Update:

released from the suppressive effects of fumagillin at higher concentrations than that of N. apis. At fumagillin concentrations that continue to impact...

Word Count : 1867

METAP2

Last Update:

target of two groups of anti-angiogenic natural products, ovalicin and fumagillin, and their analogs such as beloranib. In living organisms, the start codon...

Word Count : 3068

Medicinal uses of fungi

Last Update:

aphidicolin, brefeldin A, cephalosporin, cerulenin, citromycin, eupenifeldin, fumagillin, fusafungine, fusidic acid, helvolic acid, itaconic acid, MT81, nigrosporin...

Word Count : 1718

List of infectious diseases

Last Update:

seen in feces. Praziquantel No Microsporidia phylum Microsporidiosis PCR Fumagillin has been used in the treatment. Another agent used is albendazole. No...

Word Count : 1751

Myxobolus cerebralis

Last Update:

disease. Lastly, some drugs, such as furazolidone, furoxone, benomyl, fumagillin, proguanil and clamoxyquine, have been shown to impede spore development...

Word Count : 3280

Microsporidiosis

Last Update:

as a mycosis, however, they are highly divergent and rapidly evolving. Fumagillin has been used in the treatment. Another agent used is albendazole. Because...

Word Count : 937

Fumarranol

Last Update:

METAP2. It was derived by structural modification of the natural product fumagillin. It was originally developed as an anti-angiogenesis drug for the treatment...

Word Count : 188

Aspergillus duricaulis

Last Update:

first described in 1965. It has been reported to produce pseurotin A, fumagillin, asperpentyn, duricaulic acid, asperdurin, phthalides, chromanols, cyclopaldic...

Word Count : 147

Penicillium jensenii

Last Update:

of the genus of Penicillium which produces citrinin, griseofulvin and fumagillin. Dong, X (2005). "Decolorization of anthraquinone dye with immobilized...

Word Count : 168

Aspergillus aureoluteus

Last Update:

species was first described in 1985. It has been reported to produce fumagillin, tryptoquivaline, tryptoquivalone, pseurotin A, and viriditoxin. A. aureoluteus...

Word Count : 140

Aspergillus fumigatus

Last Update:

bronchopulmonary aspergillosis Aspergilloma Diseases of the honeybee Fumagillin RodA Galactosaminogalactan Fang W, Latgé JP (August 2018). "Microbe Profile:...

Word Count : 4593

Angiogenesis inhibitor

Last Update:

proliferation and cell migration of endothelial cells TNP-470 (an analog of fumagillin) CM101 activate immune system IFN-α downregulate angiogenesis stimulators...

Word Count : 3227

Aspergillus udagawae

Last Update:

species was first described in 1995. It has been reported to produce fumagillin, fumigaclavine A and C, fumigatins, fumiquinazolin F or G, helvolic acid...

Word Count : 236

Encephalitozoonosis

Last Update:

Polyamines, Chitin inhibitors like Nikkomycin and Fluoroquinolones, and Fumagillin for localized ocular inflammation. Consistent hygiene measures can minimize...

Word Count : 2824

Albendazole

Last Update:

by Encephalitozoon hellem or E. cuniculi, when combined with topical fumagillin Granulomatous amoebic encephalitis, when caused by the amoeba Balamuthia...

Word Count : 5037

Colony collapse disorder

Last Update:

with N. ceranae. The primary antifungal agent used against Nosema is fumagillin, which has been used in a German research project to reduce the microsporidian's...

Word Count : 15508

Endometriosis

Last Update:

include growth factor inhibitors, endogenous angiogenesis inhibitors, fumagillin analogues, statins, cyclo-oxygenase-2 inhibitors, phytochemical compounds...

Word Count : 16131

C26H34O7

Last Update:

mass: 458.54 g/mol, exact mass: 458.2305 u) may refer to: Berkeleytrione Fumagillin This set index page lists chemical structure articles associated with...

Word Count : 55

List of diseases of the honey bee

Last Update:

ventilation through the hive. Some beekeepers treat hives with agents such as fumagillin. Nosemosis can also be prevented or minimized by removing much of the...

Word Count : 7646

Bergamotene

Last Update:

For example, β-trans-bergamotene is a precursor in the biosynthesis of fumagillin, ovalicin, and related antibiotics. "Metabocard for alpha-Bergamotene...

Word Count : 532

Penicillium scabrosum

Last Update:

and cereal-containing feed. It produces several mycotoxins, including fumagillin, viridicatin, and viridicatol. P. scabrosum is classified in Penicillium...

Word Count : 105

ATC code P01

Last Update:

P01AX07 Trimetrexate P01AX08 Tenonitrozole P01AX09 Dehydroemetine P01AX10 Fumagillin P01AX11 Nitazoxanide P01AX52 Emetine, combinations P01BA01 Chloroquine...

Word Count : 321

Judah Folkman

Last Update:

discovered that a fungus, Aspergillus fumigatus, secreted a chemical, fumagillin, that inhibited angiogenesis. Takeda performed medicinal chemistry to...

Word Count : 2054

Enterocytozoon bieneusi

Last Update:

by this pathogen for the swine industry. Several treatments, including fumagillin and albendazole have showed promise in treating infection (Mathis et al...

Word Count : 1557

Rubottom oxidation

Last Update:

2S-hydroxymutilin after hydrolysis of the silyl protecting groups. Ovalicin, fumagillin, and their derivatives exhibit strong anti-angiogenesis properties and...

Word Count : 3396

Fungal isolate

Last Update:

isolates. Penicillin, cephalosporins, fusafungine, usnic acid, fusidic acid, fumagillin, brefeldin A, verrucarin A, alamethicin, are antibiotic fungal isolates...

Word Count : 966

Beloranib

Last Update:

clinical trials. Beloranib, an analog of the natural chemical compound fumagillin, is an inhibitor of the enzyme METAP2. It was originally designed as angiogenesis...

Word Count : 482

PDF Search Engine © AllGlobal.net