Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Farnesyl pyrophosphate (FPP), also known as farnesyl diphosphate (FDP), is an intermediate in the biosynthesis of terpenes and terpenoids such as sterols and carotenoids.[1] It is also used in the synthesis of CoQ (part of the electron transport chain), as well as dehydrodolichol diphosphate (a precursor of dolichol, which transports proteins to the ER lumen for N-glycosylation).
^Davis EM, Croteau R (2000). "Cyclization enzymes in the biosynthesis of monoterpenes, sesquiterpenes, and diterpenes". Topics in Current Chemistry. 209: 53–95. doi:10.1007/3-540-48146-X_2. ISBN 978-3-540-66573-1. S2CID 53419212.
and 28 Related for: Farnesyl pyrophosphate information
Farnesylpyrophosphate (FPP), also known as farnesyl diphosphate (FDP), is an intermediate in the biosynthesis of terpenes and terpenoids such as sterols...
Farnesylpyrophosphate cyclase may refer to: 5-epiaristolochene synthase, an enzyme (+)-epicubenol synthase, an enzyme This set index page lists enzyme...
formed from farnesylpyrophosphate by the addition of an isoprene unit from isopentenyl pyrophosphate. In Drosophila, geranylgeranyl pyrophosphate is synthesised...
pathway that produces longer prenyl chains such as farnesylpyrophosphate and geranylgeranyl pyrophosphate as well as many terpenes. It can be prepared in...
proceeds via formation of geranyl pyrophosphate (GPP), farnesylpyrophosphate (FPP), and geranylgeranyl pyrophosphate (GGPP). In both MVA and MEP pathways...
ketone-containing carvone. In nature, limonene is formed from geranyl pyrophosphate, via cyclization of a neryl carbocation or its equivalent as shown....
animals. When geranyl pyrophosphate reacts with isopentenyl pyrophosphate, the result is the 15-carbon farnesylpyrophosphate, which is an intermediate...
all the structural information available in the PDB for UniProt: P14324 (Human Farnesylpyrophosphate synthaseC) at the PDBe-KB. Portal: Biology v t e...
converts three monomers of isopentenyl pyrophosphate into farnesylpyrophosphate. The farnesylpyrophosphate can bind to rubber transferase to elongate...
Dimethylallyl pyrophosphate (DMAPP; or alternatively, dimethylallyl diphosphate (DMADP); also isoprenyl pyrophosphate) is an isoprenoid precursor. It...
Archaea. Squalene is biosynthesised by coupling two molecules of farnesylpyrophosphate. The condensation requires NADPH and the enzyme squalene synthase...
isopentenyl pyrophosphate isomerase. Geranyl pyrophosphate is the precursor to monoterpenes (and hence monoterpenoids). Elimination of the pyrophosphate group...
intermediates produced from geranyl pyrophosphate. Analogously hydrolysis of intermediates from farnesylpyrophosphate gives sesquiterpenoids, and hydrolysis...
produced from the universal sesquiterpene precursor farnesylpyrophosphate (also known as farnesyl diphosphate), in a two-step Mg2+-dependent reaction...
bisphosphonate group mimics the structure of pyrophosphate, it can inhibit activation of enzymes that utilize pyrophosphate. The specificity of bisphosphonate-based...
Isopentenyl pyrophosphate (IPP, isopentenyl diphosphate, or IDP) is an isoprenoid precursor. IPP is an intermediate in the classical, HMG-CoA reductase...
atmosphere. The reaction of geranyl pyrophosphate with isopentenyl pyrophosphate results in the 15-carbon farnesylpyrophosphate (FPP), which is an intermediate...
dimethylallyl pyrophosphate. This is then condensed with three molecules of isopentenyl pyrophosphate (an isomer of dimethylallyl pyrophosphate), to give...
Drimenol cyclase (EC 3.1.7.7, farnesylpyrophosphate:drimenol cyclase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphohydrolase...
pathway from farnesylpyrophosphate (FPP). FPP undergoes a rearrangement to give nerolidyl diphosphate. After the removal of pyrophosphate, the ring closes...
is chemically related to inorganic pyrophosphate, the endogenous regulator of bone turnover. But while pyrophosphate inhibits both osteoclastic bone resorption...
is biosynthesized through the head-to-head condensation of two farnesylpyrophosphate units. This coupling converts a pair of C15 components into a C30...
of osteoporosis. Its mechanism of action involves inhibition of farnesylpyrophosphate synthase activity. Shridhar Hegde and Michelle Schmidt (2009). "To...
inexpensively from Valencia oranges. Valencene is biosynthesized from farnesylpyrophosphate (FPP) by the CVS enzyme. It is used as a precursor to nootkatone...
Zoledronic acid, also known as zoledronate and sold under the brand name Zometa by Novartis among others, is a medication used to treat a number of bone...
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