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Limonene information


Limonene
Skeletal structure of the (R)-isomer
Skeletal structure of the (R)-isomer
Ball-and-stick model of the (R)-isomer
Ball-and-stick model of the (R)-isomer
Limonene extracted from orange peels.
Names
Preferred IUPAC name
1-Methyl-4-(prop-1-en-2-yl)cyclohex-1-ene
Other names
1-Methyl-4-(1-methylethenyl)cyclohexene
4-Isopropenyl-1-methylcyclohexene
p-Menth-1,8-diene
Racemic: DL-Limonene; Dipentene
Identifiers
CAS Number
  • 138-86-3 (R/S) checkY
  • 5989-27-5 (R) checkY
  • 5989-54-8 (S) checkY
3D model (JSmol)
  • Interactive image
ChEBI
  • CHEBI:15384 checkY
ChEMBL
  • ChEMBL449062 (R) checkY
ChemSpider
  • 20939 (R/S) checkY
  • 388386 (S) checkY
  • 389747 (R) checkY
ECHA InfoCard 100.004.856 Edit this at Wikidata
KEGG
  • D00194 checkY
PubChem CID
  • 22311 (R/S)
  • 439250 (S)
UNII
  • 9MC3I34447 (R/S) checkY
  • GFD7C86Q1W (R) checkY
  • 47MAJ1Y2NE (S) checkY
CompTox Dashboard (EPA)
  • DTXSID2029612 Edit this at Wikidata
InChI
  • InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3 checkY
    Key: XMGQYMWWDOXHJM-UHFFFAOYSA-N checkY
SMILES
  • CC1=CCC(CC1)C(=C)C
Properties
Chemical formula
C10H16
Molar mass 136.238 g·mol−1
Appearance colorless liquid
Odor Orange
Density 0.8411 g/cm3
Melting point −74.35 °C (−101.83 °F; 198.80 K)
Boiling point 176 °C (349 °F; 449 K)
Solubility in water
Insoluble
Solubility Miscible with benzene, chloroform, ether, CS2, and oils
soluble in CCl4
Chiral rotation ([α]D)
87–102°
Refractive index (nD)
1.4727
Thermochemistry
Std enthalpy of
combustion cH298)
−6.128 MJ mol−1
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
Skin sensitizer / Contact dermatitis – After aspiration, pulmonary oedema, pneumonitis, and death[1]
GHS labelling:
Pictograms
GHS02: FlammableGHS07: Exclamation markGHS08: Health hazardGHS09: Environmental hazard
Signal word
Danger
Hazard statements
H226, H304, H315, H317, H410
Precautionary statements
P210, P233, P235, P240, P241, P242, P243, P261, P264, P272, P273, P280, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P312, P333+P313, P362, P370+P378, P391, P403+P233, P405, P501
NFPA 704 (fire diamond)
NFPA 704 four-colored diamondHealth 2: Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury. E.g. chloroformFlammability 2: Must be moderately heated or exposed to relatively high ambient temperature before ignition can occur. Flash point between 38 and 93 °C (100 and 200 °F). E.g. diesel fuelInstability 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g. liquid nitrogenSpecial hazards (white): no code
2
2
0
Flash point 50 °C (122 °F; 323 K)
Autoignition
temperature
237 °C (459 °F; 510 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Limonene is a colorless liquid aliphatic hydrocarbon classified as a cyclic monoterpene, and is the major component in the volatile oil of citrus fruit peels.[1] The (+)-isomer, occurring more commonly in nature as the fragrance of oranges, is a flavoring agent in food manufacturing.[1][2] It is also used in chemical synthesis as a precursor to carvone and as a renewables-based solvent in cleaning products.[1] The less common (-)-isomer has a piny, turpentine-like odor, and is found in the edible parts of such plants as caraway, dill, and bergamot orange plants.[3]

Limonene takes its name from Italian limone ("lemon").[4] Limonene is a chiral molecule, and biological sources produce one enantiomer: the principal industrial source, citrus fruit, contains (+)-limonene (d-limonene), which is the (R)-enantiomer.[1] (+)-Limonene is obtained commercially from citrus fruits through two primary methods: centrifugal separation or steam distillation.

  1. ^ a b c d e "D-Limonene". PubChem Compound Database. National Center for Biotechnology Information, US National Library of Medicine. 2017. Retrieved 22 December 2017.
  2. ^ Cite error: The named reference Ullmann was invoked but never defined (see the help page).
  3. ^ "Molecule of the Week Archive: Limonene". ACS.org. American Chemical Society. 1 November 2021. Retrieved 5 November 2021.
  4. ^ "limonene". merriam-webster.com. Merriam-Webster. 22 September 2023. Retrieved 23 September 2023.

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Limonene

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Limonene synthase may refer to one of two enzymes: (R)-limonene synthase (4S)-limonene synthase This disambiguation page lists articles associated with...

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composed of mostly (greater than 90%) d-limonene, and is often used in place of pure d-limonene. D-limonene can be extracted from the oil by distillation...

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Menthol

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geranyl diphosphate. (−)-limonene synthase (LS) catalyzes the cyclization of geranyl diphosphate to (−)-limonene. (−)-Limonene-3-hydroxylase (L3OH), using...

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beta-myrcene, limonene, 1,8-cineole, Z-beta-ocimene (J. Agri. & Food Chem., 44, 1096, 1996) Zanthoxylum armatum (Nepal) — linalool (50%), limonene, methyl cinnamate...

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Monoterpene

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eucalyptol, ocimene, myrcene, limonene, linalool, menthol, camphene and pinenes are used in perfumes and cosmetic products. Limonene and perillyl alcohol are...

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Neroli

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sensitisation due to a high content of aromatic terpenes; e.g., linalool, limonene, farnesol, geraniol and citral. It blends well with any citrus oil, various...

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Carvone

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may be synthetically prepared from limonene via limonene nitrosochloride which may be formed by treatment of limonene with isoamyl nitrite in glacial acetic...

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is a commonly held misconception that (+)-limonene is found in oranges (causing its smell), and (–)-limonene is found in lemons (causing its smell). In...

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the fruit, and is composed principally of limonene, which makes up around 93% of the total. Besides limonene and alpha-pinene (0.34%), both of which are...

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in the presence of sulfuric acid. An alternative route starts from limonene: Limonene reacts with trifluoroacetic acid in a Markovnikov addition to a trifluoroacetate...

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Henrique; Rozza, Ariane Leite (2019-09-04). "Gastroprotective effect of limonene in rats: Influence on oxidative stress, inflammation and gene expression"...

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monoterpenes alpha- and beta-pinene, with lesser amounts of carene, camphene, limonene, and terpinolene. Substitutes include white spirit or other petroleum distillates...

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Perillyl alcohol and its precursor limonene are naturally occurring monocyclic terpenes derived from the mevalonate pathway in plants. Perillyl alcohol...

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Citronella oil

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(5–15%), geraniol (18–20%) and geranyl acetate (2%), citronellol (6–8%), limonene (9–11%), and methyl isoeugenol (7–11%). CAS: 91771-61-8 CAS: 8000-29-1...

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Bergamot essential oil

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compounds as coumarins and furanocoumarins. The main compounds in the oil are limonene, linalyl acetate, linalool, γ-terpinene and β-pinene, and in smaller quantities...

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including cannabis. The most common dominant terpenes found in this strain are limonene, which is also found in citrus fruits such as lemons, and terpinolene....

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anthranilate(50%), γ-Terpinene(15%), Limonene(5%), p-Cymene(3%) Petitgrain citronnier Citrus limon Lemon leaves, (twigs, branches) Limonene, Citral, Geranyl acetate...

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mineral spirits to make them easier to work with.[citation needed] Limonene and D-limonene are less toxic alternatives for mineral spirits.[citation needed]...

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alpha-pinene, beta-pinene, delta-3 carene, and sabinene, the monocyclic terpenes limonene and terpinolene, and smaller amounts of the tricyclic sesquiterpenes, longifolene...

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