Elastin is a protein that in humans is encoded by the ELN gene. Elastin is a key component of the extracellular matrix in gnathostomes (jawed vertebrates).[5] It is highly elastic and present in connective tissue allowing many tissues in the body to resume their shape after stretching or contracting.[6] Elastin helps skin to return to its original position when it is poked or pinched. Elastin is also an important load-bearing tissue in the bodies of vertebrates and used in places where mechanical energy is required to be stored.[7]
^ abcGRCh38: Ensembl release 89: ENSG00000049540 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000029675 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Mithieux SM, Weiss AS (2005). "Elastin". Advances in Protein Chemistry. 70: 437–461. doi:10.1016/S0065-3233(05)70013-9. ISBN 9780120342709. PMID 15837523.
Elastin is a protein that in humans is encoded by the ELN gene. Elastin is a key component of the extracellular matrix in gnathostomes (jawed vertebrates)...
tissues contain high amounts of elastins. Elastins are synthesized by fibroblasts and smooth muscle cells. Elastins are highly insoluble, and tropoelastins...
ganglioside substrates and other glycoconjugates. The GLB1 gene also encodes an elastin binding protein. In corn (Zea mays), Glb1 is a gene coding for the storage...
component of the extracellular matrix composed of bundles of proteins (elastin) which are produced by a number of different cell types including fibroblasts...
Most structural proteins are fibrous proteins; for example, collagen and elastin are critical components of connective tissue such as cartilage, and keratin...
uniquely in elastin, a protein found in connective tissue such as skin, lungs, and elastic arteries. Desmosine is a component of elastin and cross links...
specialized organs such as the cornea.: 161 Elastic fibers, made from elastin and fibrillin, also provide resistance to stretch forces.: 171 They are...
and pelvic fins, arms, legs, wings, etc.), the elastomeric protein of elastin, and a horizontal semicircular canal of the inner ear, along with physiological...
likewise has a high percentage of glycine. The connective tissue protein elastin also has a high percentage of both glycine and alanine. Silk fibroin, considered...
results in a decreased activity of the lysyl oxidase enzyme, affecting elastin, a key component in vessel walls. Copper deficiency results in vessel wall...
vocal fold. There is a steady increase in the elastin content of the lamina propria as humans age (elastin is a yellow scleroprotein, the essential constituent...
antibody binding) demonstrated the presence of proteins such as collagen, elastin, and laminin. Both specimens yielded collagen protein sequences that were...
milk glands, the breast is also composed of connective tissues (collagen, elastin), white fat, and the suspensory Cooper's ligaments. Sensation in the breast...
elastic fiber networks and collagen type II fibers. The principal protein is elastin. Elastic cartilage is histologically similar to hyaline cartilage but contains...
Gosilin, J.M.; Aaron, B.B (1981). "Elastin as a Random-network elastomer, a mechanical and optical analysis of single elastin fibers". Biopolymers. 20 (6):...
has a particularly high affinity for bilirubin deposition due to high elastin content. Slight increases in serum bilirubin can, therefore, be detected...
thought to cause fibroblasts to produce more elastin fibers, which are more twisted than normal elastin fibers and may lead to the degradation of the...
association with the development of intracranial aneurysms, including perlecan, elastin, collagen type 1 A2, endothelial nitric oxide synthase, endothelin receptor...
composed of matrix components such as collagen (which provides strength), elastin (which provides elasticity), and extrafibrillar matrix, an extracellular...
in a dose-dependent manner. In hypertensive rats, minoxidil increases elastin level in the mesenteric, abdominal, and renal arteries by a decrease in...
with blood vessels and nerves. It consists of loose connective tissue and elastin. The main cell types are fibroblasts, macrophages and adipocytes (the subcutaneous...
the alveolar walls. Elastin is the key protein of the extracellular matrix and is the main component of the elastic fibres. Elastin gives the necessary...
found in elastin. Isodesmosine is an isomeric pyridinium-based amino acid resulting from the condensation of four lysine residues between elastin proteins...
elastosis, also known as solar elastosis, is an accumulation of abnormal elastin (elastic tissue) in the dermis of the skin, or in the conjunctiva of the...
the larynx or glottis that vibrate to produce sound. Other species have elastin-rich vocal cords. Due to their heavy shells, turtles are slow-moving on...
two copies of the elastin gene. Since 98-99% of individuals with WS lack half of the 7q11.23 region of chromosome 7, where the elastin gene is located,...
more common than their thoracic counterpart. One reason for this is that elastin, the principal load-bearing protein present in the wall of the aorta, is...