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Enteric coating information


An enteric coating is a polymer barrier applied to oral medication that prevents its dissolution or disintegration in the gastric environment.[1] This helps by either protecting drugs from the acidity of the stomach, the stomach from the detrimental effects of the drug, or to release the drug after the stomach (usually in the upper tract of the intestine).[2] Some drugs are unstable at the pH of gastric acid and need to be protected from degradation. Enteric coating is also an effective method to obtain drug targeting (such as gastro-resistant drugs). Other drugs such as some anthelmintics may need to reach a high concentration in a specific part of the intestine.[1] Enteric coating may also be used during studies as a research tool to determine drug absorption.[3] Enteric-coated medications pertain to the "delayed action" dosage form category. Tablets, mini-tablets, pellets and granules (usually filled into capsule shells) are the most common enteric-coated dosage forms.[3]

  1. ^ a b Tarcha, Peter J. (1990). Polymers for Controlled Drug Delivery. CRC Press. ISBN 9780849356520.
  2. ^ Bundgaard, Hans; Hansen, Anne Bagger; Kofod, Helmer (1982). Optimization of drug delivery: proceedings of the Alfred Benzon Symposium 17 held at the premises of the Royal Danish Academy of Sciences and Letters, Copenhagen 31 May-4 June 1981. Munksgaard. ISBN 9788716089793.
  3. ^ a b Wen, Hong; Park, Kinam (2011). Oral Controlled Release Formulation Design and Drug Delivery: Theory to Practice. John Wiley & Sons. ISBN 9781118060322.

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Enteric coating

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(usually filled into capsule shells) are the most common enteric-coated dosage forms. Most enteric coatings work by presenting a surface that is stable at the...

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Film coating

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modified-release dosage and enteric coatings. Organic solvent use in film coating is typically used to incorporate protective coatings to the oral dosage form...

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Cellulose acetate phthalate

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polymer phthalate in the formulation of pharmaceuticals, such as the enteric coating of tablets or capsules and for controlled release formulations. It...

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Aspirin

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Enteric coating on aspirin may be used in manufacturing to prevent release of aspirin into the stomach to reduce gastric harm, but enteric coating does...

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Polyvinyl acetate phthalate

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polymer phthalate in the formulation of pharmaceuticals, such as the enteric coating of tablets or capsules. It is a vinyl acetate polymer that is partially...

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Rosin

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derivatives show excellent film forming and coating properties. They are also used for tablet film and enteric coating purpose. Rosins have also been used to...

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Optical coating

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An optical coating is one or more thin layers of material deposited on an optical component such as a lens, prism or mirror, which alters the way in which...

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Phthalic anhydride

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cellulose acetate gives cellulose acetate phthalate (CAP), a common enteric coating excipient that has also been shown to have antiviral activity. Phthalic...

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Duloxetine

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uptake. Absorption: Duloxetine is acid labile, and is formulated with enteric coating to prevent degradation in the stomach. Duloxetine has good oral bioavailability...

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Chitosan

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(2005). "Evaluation of chitosan succinate and chitosan phthalate as enteric coating polymers for diclofenac sodium tablets". Journal of Drug Delivery Science...

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Irritable bowel syndrome

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established, however, and caution is required not to chew or break the enteric coating; otherwise, gastroesophageal reflux may occur as a result of lower...

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Rabeprazole

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rabeprazole that enters the body, but it does delay its onset of effect by about 1.7 hours. Once rabeprazole is taken by mouth, the enteric coating of the tablet...

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Fusion bonded epoxy coating

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bonded epoxy coating, also known as fusion-bond epoxy powder coating and commonly referred to as FBE coating, is an epoxy-based powder coating that is widely...

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Excipient

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Enterics control the rate of drug release and determine where the drug will be released in the digestive tract. Materials used for enteric coatings include...

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Methacrylic acid

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and Drug Administration. 2018-03-06. Retrieved 2019-04-03. "Aqueous enteric coatings with methacrylic acid copolymer type C on acidic and basic drugs in...

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Anodizing

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cosmetic effects, either with thick porous coatings that can absorb dyes or with thin transparent coatings that add reflected light wave interference...

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Electrostatic coating

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Electrostatic coating is a manufacturing process that employs charged particles to more efficiently paint a workpiece. Paint, in the form of either powdered...

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Thermal barrier coating

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Thermal barrier coatings (TBCs) are advanced materials systems usually applied to metallic surfaces on parts operating at elevated temperatures, such as...

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Paint

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object being painted). This is called "powder coating" an object. In a gas phase application, the coating composition is introduced (if gaseous), vaporized...

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Phthalates

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phthalate (CAP), all of which are used to make enteric coatings for tablet and capsule medications. These coatings protect drugs from the acidity of the stomach...

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Waterproofing

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or pitch. Modern items may be waterproofed by applying water-repellent coatings or by sealing seams with gaskets or o-rings. Waterproofing is used in reference...

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Physical vapor deposition

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vacuum deposition methods which can be used to produce thin films and coatings on substrates including metals, ceramics, glass, and polymers. PVD is characterized...

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