Group of cells allowing a pathogen to infect nearby endothelium
Endothelial cell tropism or endotheliotropism is a type of tissue tropism or host tropism that characterizes an pathogen's ability to recognize and infect an endothelial cell. Pathogens, such as viruses, can target a specific tissue type or multiple tissue types. Like other cells, the endothelial cell possesses several features that supports a productive viral infection a cell including, cell surface receptors, immune responses, and other virulence factors.[1] Endothelial cells are found in various tissue types such as in the capillaries, veins, and arteries in the human body. As endothelial cells line these blood vessels and critical networks that extend access to various human organ systems, the virus entry into these cells can be detrimental to virus spread across the host system and affect clinical course of disease. Understanding the mechanisms of how viruses attach, enter, and control endothelial functions and host responses inform infectious disease understanding and medical countermeasures.
^Fosse, Johanna Hol; Haraldsen, Guttorm; Falk, Knut; Edelmann, Reidunn (2021). "Endothelial Cells in Emerging Viral Infections". Frontiers in Cardiovascular Medicine. 8: 95. doi:10.3389/fcvm.2021.619690. ISSN 2297-055X. PMC 7943456. PMID 33718448.
and 25 Related for: Endothelial cell tropism information
Endothelialcelltropism or endotheliotropism is a type of tissue tropism or host tropism that characterizes an pathogen's ability to recognize and infect...
The endothelium (pl.: endothelia) is a single layer of squamous endothelialcells that line the interior surface of blood vessels and lymphatic vessels...
surface of the macrophages and T cells. Thus HIV can enter T cells and macrophages Endothelialcelltropism Host tropism McCall, LI; Siqueira-Neto, JL;...
which increases E. coli infectivity and tropism for human gut cells. Endothelialcelltropism Tissue tropism Douam, Florian; Gaska, Jenna M.; Winer, Benjamin...
Interleukin Lipoxin Neurogenic inflammation Substance P Stress (biology) EndothelialCellTropism All these signs may be observed in specific instances, but no single...
μm. The precise cellular tropism for NM has not yet been determined, but a study from 2019 showed that human endothelialcells are certainly one of the...
host cell surfaces and also components in the extracellular matrix. These molecules also control host specificity and regulate tropism (tissue- or cell-specific...
reorganization creates intercellular gaps in endothelialcells. The gaps lead to increased endothelial permeability and allow blood to escape from the...
environment stimulates muscle cells in the surrounding tissue to upregulate and secrete angiogenic cytokines, such as vascular endothelial growth factor (VEGF)...
immunofluorescence. Single cell level qPCR can also be performed with the CTCs isolated from blood.[citation needed] The organ tropism of patient-derived CTC...
Overlapping Roles of Nipah Virus P Gene Products in Modulating the Human EndothelialCell Antiviral Response". PLOS ONE. 7 (10): e47790. Bibcode:2012PLoSO.....
colonize a primary niche, the endothelialcells. Every five days, some of the Bartonella bacteria in the endothelialcells are released into the blood stream...
replication within the cytoplasm of living eukaryotic host cells (typically endothelialcells). Accordingly, Rickettsia species cannot grow in artificial...
Ehrlichia phagocytophilum) is a Gram-negative bacterium that is unusual in its tropism to neutrophils. It causes anaplasmosis in sheep and cattle, also known...
transmitted between polymorphonuclear leukocytes (PM-NLs) and endothelialcells. Infected endothelialcells produce cytokines that attract PM-NLs, which then adhere...
determines the virus' host range (which organisms it can infect) and celltropism (which cells or tissues it can infect within an organism). Spike glycoprotein...
culturing including rat glioma cells, human lung cells, and human brain microvascular endothelialcells. These animal cells are added to a specified sterilized...
stem and progenitor cells (HSPCs). In a study designed to enhance the outcomes of vascular transplant through vascular endothelialcell gene therapy, the...
cells from continuing through the cell cycle (i.e., cell cycle arrest). Type II IFN can also prevent tumor growth by indirectly acting on endothelial...
tissues—are also motile in special physiological (e.g., mast cell, fibroblast, endothelialcells) or pathological conditions (e.g., metastases). Chemotaxis...
breaks. After infection, endothelialcells (cells lining the inside of blood vessels), liver cells, and several types of immune cells such as macrophages,...
normal red cells, thereby restricting multiplication in the former. In addition, binding of parasitized sickle cells to endothelialcells is significantly...
Global Information