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Effector cell information


In cell biology, an effector cell is any of various types of cell that actively responds to a stimulus and effects some change (brings it about).

Examples of effector cells include:

  • The muscle, gland or organ cell capable of responding to a stimulus at the terminal end of an efferent nerve fiber
  • Plasma cell, an effector B cell in the immune system
  • Effector T cells, T cells that actively respond to a stimulus
  • Cytokine-induced killer cells, strongly productive cytotoxic effector cells that are capable of lysing tumor cells[1]
  • Microglia, a glial effector cell that reconstructs the Central nervous system after a bone marrow transplant[2]
  • Fibroblast, a cell that is most commonly found within connective tissue[3]
  • Mast cell, the primary effector cell involved in the development of asthma[4]
  1. ^ IG, Schmidt-Wolf; P, Lefterova; BA, Mehta; LP, Fernandez; D, Huhn; KG, Blume; IL, Weissman; RS, Negrin (1993-12-01). "Phenotypic characterization and identification of effector cells involved in tumor cell recognition of cytokine-induced killer cells". Experimental Hematology. 21 (13): 1673–9. ISSN 0301-472X. PMID 7694868.
  2. ^ Krivit, W (July 1995). "Microglia: The effector cell for reconstitution of the central nervous system following bone marrow transplantation for lysosomal and peroxisomal storage diseases". Cell Transplantation. 4 (4): 385–392. doi:10.1016/0963-6897(95)00021-O. PMID 7582569.
  3. ^ Lorenz, H. Peter; Lin, Richard Y.; Longaker, Michael T.; Whitby, David J.; Adzick, N. Scott (November 1995). "The fetal fibroblast: the effector cell of scarless fetal skin repair". Plastic and Reconstructive Surgery. 96 (6): 1251–9, discussion 1260–1. doi:10.1097/00006534-199511000-00001. PMID 7480221. S2CID 38388476.
  4. ^ Holgate, S (February 1986). "The mast cell as a primary effector cell in the pathegenesis of asthma". Journal of Allergy and Clinical Immunology. 77 (2): 274–282. doi:10.1016/S0091-6749(86)80104-X. PMID 2418090.

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Effector cell

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In cell biology, an effector cell is any of various types of cell that actively responds to a stimulus and effects some change (brings it about). Examples...

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Memory T cell

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effector cells. Effector cells undergo active cytokine secretion and other effector activities. After antigen clearance, some of these effector cells...

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Natural killer cell

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circulation. NK cells differ from natural killer T cells (NKTs) phenotypically, by origin and by respective effector functions; often, NKT cell activity promotes...

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Regulatory T cell

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disease. Treg cells are immunosuppressive and generally suppress or downregulate induction and proliferation of effector T cells. Treg cells express the...

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T helper cell

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and their effector cytokines are IFN-γ and IL-2. The main effector cells of Th1 immunity are macrophages as well as CD8 T cells, IgG B cells, and IFN-γ...

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Effector

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Look up effector in Wiktionary, the free dictionary. Effector may refer to: Effector (biology), a molecule that binds to a protein and thereby alters the...

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B cell

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cell is activated by an antigen, it proliferates and differentiates into an antibody-secreting effector cell, known as a plasmablast or plasma cell....

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T cell

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used to distinguish murine naive from memory T cells). Effector memory T cells (TEM cells and TEMRA cells) express CD45RO but lack expression of CCR7 and...

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Antibody opsonization

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This allows the antibody binding of an immune effector cell via its Fc domain. Antibody-dependent cell-mediated inherent mediation then triggers a release...

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Plasma cell

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Plasma cells, also called plasma B cells or effector B cells, are white blood cells that originate in the lymphoid organs as B cells and secrete large...

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Adaptive immune system

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helper T cell (predominately Th2 type)), it further differentiates into an effector cell, known as a plasma cell. Plasma cells are short-lived cells (2–3...

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Acute lymphoblastic leukemia

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T-cells. This effect has been attributed to making an immunologic space within which the cells populate. The process as a whole result in an effector cell...

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Immunological memory

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the tissue and represent an immediate effector cell population. These cells were named memory effector T cells (TEM). After repeated stimulation they...

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CAR T cell

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G, Waks T, Eshhar Z (February 1989). "Generation of effector T cells expressing chimeric T cell receptor with antibody type-specificity". Transplantation...

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Synapse

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permits a neuron (or nerve cell) to pass an electrical or chemical signal to another neuron or to the target effector cell. Synapses are essential to...

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Gamma delta T cell

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Gamma delta T cells (γδ T cells) are T cells that have a γδ T-cell receptor (TCR) on their surface. Most T cells are αβ (alpha beta) T cells with TCR composed...

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Immune checkpoint

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ligand, CD70, on lymphocytes and dendritic cells. CD27 costimulation is known to suppress Th17 effector cell function. The American biotech company Celldex...

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Cytotoxic T cell

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these naive and memory T cells are activated, giving rise to effector T cells that have the capacity to kill pathogens or tumor cells. The threshold for activation...

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Innate lymphoid cell

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expressing NK cell markers, ILC3s differ greatly from NK cells, with different developmental pathways and effector functions. LTi cells are considered...

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Immunotherapy

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of cancer. Cell-based immunotherapies are effective for some cancers. Immune effector cells such as lymphocytes, macrophages, dendritic cells, natural killer...

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Mast cell

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mast cells serve as the main effector cell through which pathogens can affect the gut–brain axis. In the gastrointestinal tract, mucosal mast cells are...

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Cell polarity

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between neurons and effector cells. Many cell types are capable of migration, such as leukocytes and fibroblasts, and in order for these cells to move in one...

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Antibody

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cell activity: it is where effector molecules bind to, triggering various effects after the antibody Fab region binds to an antigen. Effector cells (such...

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Robot end effector

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manipulators, the end effector means the last link (or end) of the robot. At this endpoint, the tools are attached. In a wider sense, an end effector can be seen...

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Neuron

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(motor neurons) transmit signals from the central nervous system to the effector cells. Interneurons connect neurons within specific regions of the central...

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