Chemical compound
Dextrothyroxine Trade names Choloxin Other names D -3,5,3',5'-tetraiodothyronineAHFS/Drugs.com Multum Consumer Information ATC code Legal status
(2R )-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid
CAS Number PubChem CID DrugBank ChemSpider UNII ChEBI ChEMBL CompTox Dashboard (EPA ) DTXSID60199000 ECHA InfoCard 100.000.094 Formula C 15 H 11 I 4 N O 4 Molar mass 776.874 g·mol−1 3D model (JSmol)
O=C(O)[C@H](N)Cc2cc(I)c(Oc1cc(I)c(O)c(I)c1)c(I)c2
InChI=1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m1/s1
Key:XUIIKFGFIJCVMT-GFCCVEGCSA-N
Dextrothyroxine (trade name Choloxin ) is a dextrorotary isomer of thyroxine.[1] It saw research as a cholesterol-lowering drug[2] but was pulled due to cardiac side-effects. It increases hepatic lipase which in turn improves utilization of triglycerides and decreases levels of lipoprotein(a) in blood serum.[3]
^ "Dextrothyroxine (Code C61719)". NCI Thesaurus . National Cancer Institute. 2011-11-14. Retrieved 2020-01-28 .
^ Bantle JP, Hunninghake DB, Frantz ID, Kuba K, Mariash CN, Oppenheimer JH (September 1984). "Comparison of effectiveness of thyrotropin-suppressive doses of D- and L-thyroxine in treatment of hypercholesterolemia". The American Journal of Medicine . 77 (3): 475–81. doi:10.1016/0002-9343(84)90107-4. PMID 6475988.
^ Bommer C, Werle E, Walter-Sack I, Keller C, Gehlen F, Wanner C, et al. (January 1998). "D-thyroxine reduces lipoprotein(a) serum concentration in dialysis patients". Journal of the American Society of Nephrology . 9 (1): 90–6. doi:10.1681/ASN.V9190. PMID 9440092.
Last Update: 2024-01-14T11:04:06Z
Dextrothyroxine (trade name Choloxin) is a dextrorotary isomer of thyroxine. It saw research as a cholesterol-lowering drug but was pulled due to cardiac...
Word Count : 159
Last Update: 2024-06-25T16:53:36Z
Solid drugs such as tablets contain the pentahydrate form of the salt. Dextrothyroxine is the mirror form of levothryoxine with the opposite, non-natural...
Word Count : 3386
Last Update: 2024-06-06T16:17:15Z
Agonists Dextrothyroxine DIMIT DITPA Levothyroxine Liothyronine Liotrix Thyroxine Tiratricol (TRIAC) Triiodothyronine Thyroid extract Thyromimetics (selective...
Word Count : 11803
Last Update: 2024-06-22T20:56:04Z
Agonists Dextrothyroxine DIMIT DITPA Levothyroxine Liothyronine Liotrix Thyroxine Tiratricol (TRIAC) Triiodothyronine Thyroid extract Thyromimetics (selective...
Word Count : 4803
Last Update: 2024-05-19T03:03:35Z
Agonists Dextrothyroxine DIMIT DITPA Levothyroxine Liothyronine Liotrix Thyroxine Tiratricol (TRIAC) Triiodothyronine Thyroid extract Thyromimetics (selective...
Word Count : 2535
Last Update: 2024-06-25T07:21:36Z
Phenylalanine NP-118809 Gababutin Ziconotide (Approved for pain) Ethanol Dextrothyroxine (Agonist of α2δ instead of inhibiting it) Ethioninie Suloctidil Terodiline...
Word Count : 13447
Last Update: 2023-12-11T23:31:59Z
Agonists Dextrothyroxine DIMIT DITPA Levothyroxine Liothyronine Liotrix Thyroxine Tiratricol (TRIAC) Triiodothyronine Thyroid extract Thyromimetics (selective...
Word Count : 495
Last Update: 2024-06-13T02:46:31Z
Agonists Dextrothyroxine DIMIT DITPA Levothyroxine Liothyronine Liotrix Thyroxine Tiratricol (TRIAC) Triiodothyronine Thyroid extract Thyromimetics (selective...
Word Count : 456
Last Update: 2024-06-17T06:00:58Z
Agonists Dextrothyroxine DIMIT DITPA Levothyroxine Liothyronine Liotrix Thyroxine Tiratricol (TRIAC) Triiodothyronine Thyroid extract Thyromimetics (selective...
Word Count : 1439
Last Update: 2024-06-24T23:52:50Z
Agonists Dextrothyroxine DIMIT DITPA Levothyroxine Liothyronine Liotrix Thyroxine Tiratricol (TRIAC) Triiodothyronine Thyroid extract Thyromimetics (selective...
Word Count : 1150
Last Update: 2024-03-09T00:51:02Z
Agonists Dextrothyroxine DIMIT DITPA Levothyroxine Liothyronine Liotrix Thyroxine Tiratricol (TRIAC) Triiodothyronine Thyroid extract Thyromimetics (selective...
Word Count : 1979
Last Update: 2024-06-11T02:34:14Z
Agonists Dextrothyroxine DIMIT DITPA Levothyroxine Liothyronine Liotrix Thyroxine Tiratricol (TRIAC) Triiodothyronine Thyroid extract Thyromimetics (selective...
Word Count : 2153
Last Update: 2024-03-22T11:16:36Z
Agonists Dextrothyroxine DIMIT DITPA Levothyroxine Liothyronine Liotrix Thyroxine Tiratricol (TRIAC) Triiodothyronine Thyroid extract Thyromimetics (selective...
Word Count : 1416
Last Update: 2023-12-16T21:54:29Z
Agonists Dextrothyroxine DIMIT DITPA Levothyroxine Liothyronine Liotrix Thyroxine Tiratricol (TRIAC) Triiodothyronine Thyroid extract Thyromimetics (selective...
Word Count : 1957
Last Update: 2023-10-08T19:03:44Z
Agonists Dextrothyroxine DIMIT DITPA Levothyroxine Liothyronine Liotrix Thyroxine Tiratricol (TRIAC) Triiodothyronine Thyroid extract Thyromimetics (selective...
Word Count : 694
Last Update: 2024-06-14T21:56:58Z
Agonists Dextrothyroxine DIMIT DITPA Levothyroxine Liothyronine Liotrix Thyroxine Tiratricol (TRIAC) Triiodothyronine Thyroid extract Thyromimetics (selective...
Word Count : 11029
Last Update: 2024-06-24T23:35:46Z
Agonists Dextrothyroxine DIMIT DITPA Levothyroxine Liothyronine Liotrix Thyroxine Tiratricol (TRIAC) Triiodothyronine Thyroid extract Thyromimetics (selective...
Word Count : 5787
Last Update: 2023-12-21T03:48:30Z
Agonists Dextrothyroxine DIMIT DITPA Levothyroxine Liothyronine Liotrix Thyroxine Tiratricol (TRIAC) Triiodothyronine Thyroid extract Thyromimetics (selective...
Word Count : 689
Last Update: 2024-06-24T23:59:35Z
Agonists Dextrothyroxine DIMIT DITPA Levothyroxine Liothyronine Liotrix Thyroxine Tiratricol (TRIAC) Triiodothyronine Thyroid extract Thyromimetics (selective...
Word Count : 2756
Last Update: 2024-06-01T13:48:25Z
Agonists Dextrothyroxine DIMIT DITPA Levothyroxine Liothyronine Liotrix Thyroxine Tiratricol (TRIAC) Triiodothyronine Thyroid extract Thyromimetics (selective...
Word Count : 7786
Last Update: 2024-01-04T06:17:44Z
Agonists Dextrothyroxine DIMIT DITPA Levothyroxine Liothyronine Liotrix Thyroxine Tiratricol (TRIAC) Triiodothyronine Thyroid extract Thyromimetics (selective...
Word Count : 4437
Last Update: 2024-06-20T21:05:33Z
Agonists Dextrothyroxine DIMIT DITPA Levothyroxine Liothyronine Liotrix Thyroxine Tiratricol (TRIAC) Triiodothyronine Thyroid extract Thyromimetics (selective...
Word Count : 1505
Last Update: 2024-03-26T01:33:26Z
therapy (5 mg/day oral conjugated estrogens), clofibrate (1.8 g/day), dextrothyroxine (6 mg/day), niacin (3 g/day), and placebo (lactose 3.8 mg/day). The...
Word Count : 531
Last Update: 2024-06-10T08:18:52Z
Agonists Dextrothyroxine DIMIT DITPA Levothyroxine Liothyronine Liotrix Thyroxine Tiratricol (TRIAC) Triiodothyronine Thyroid extract Thyromimetics (selective...
Word Count : 2460
Last Update: 2024-05-22T00:01:54Z
Agonists Dextrothyroxine DIMIT DITPA Levothyroxine Liothyronine Liotrix Thyroxine Tiratricol (TRIAC) Triiodothyronine Thyroid extract Thyromimetics (selective...
Word Count : 1836
Last Update: 2023-12-18T04:44:59Z
(pyridylcarbinol) C10AD06 Acipimox C10AD52 Nicotinic acid, combinations C10AX01 Dextrothyroxine C10AX02 Probucol C10AX03 Tiadenol C10AX05 Meglutol C10AX06 Omega-3-triglycerides...
Word Count : 434
Last Update: 2024-03-14T02:57:33Z
Agonists Dextrothyroxine DIMIT DITPA Levothyroxine Liothyronine Liotrix Thyroxine Tiratricol (TRIAC) Triiodothyronine Thyroid extract Thyromimetics (selective...
Word Count : 1769
Last Update: 2024-02-04T17:51:06Z
Agonists Dextrothyroxine DIMIT DITPA Levothyroxine Liothyronine Liotrix Thyroxine Tiratricol (TRIAC) Triiodothyronine Thyroid extract Thyromimetics (selective...
Word Count : 220