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Desiccated thyroid extract information


Desiccated thyroid extract
Combination of
ThyroxineThyroid hormone
TriiodothyronineThyroid hormone
Clinical data
Trade namesArmour Thyroid, NP Thyroid, Nature-Throid
Other namesNatural thyroid, natural thyroid hormones, pork thyroid, thyroid USP, thyroid BP
AHFS/Drugs.comMonograph
License data
  • US DailyMed: Thyroid porcine
Routes of
administration
By mouth
ATC code
  • None
Legal status
Legal status
  • US: ℞-only
Identifiers
CAS Number
  • 8001-24-9

Desiccated thyroid, also known as thyroid extract, is thyroid gland that has been dried and powdered for medical use.[1] It is used to treat hypothyroidism.,[1] but less preferred than levothyroxine.[1] It is taken by mouth.[1] Maximal effects may take up to three weeks to occur.[1]

Side effects may occur from excessive doses.[1] This may include weight loss, fever, headache, anxiety, trouble sleeping, arrythmias, and heart failure.[1] Other side effects may include allergic reactions.[1] Use in pregnancy and breastfeeding is generally safe.[2] Regular blood tests are recommended to verify the appropriateness of the dose.[1] They contain a mixture of thyroxine (T4) and triiodothyronine (T3).[1]

Desiccated thyroid has been used since the late 1800s.[3] It is usually made from pigs, sheep, or cows.[4] It is available as a generic medication.[1] In 2021, it was the 119th most commonly prescribed medication in the United States, with more than 5 million prescriptions.[5][6] Usage has decreased since the 1960s.[3]

  1. ^ a b c d e f g h i j k "Thyroid Monograph for Professionals". Drugs.com. American Society of Health-System Pharmacists. Retrieved 8 April 2019.
  2. ^ "Thyroid desiccated Use During Pregnancy". Drugs.com. Retrieved 9 April 2019.
  3. ^ a b Jameson JL, Groot LJ (2010). Endocrinology - E-Book: Adult and Pediatric. Elsevier Health Sciences. p. 1608. ISBN 9781455711260.
  4. ^ Thomas JA, Keenan EJ (2012). Principles of Endocrine Pharmacology. Springer Science & Business Media. p. 78. ISBN 9781468450361.
  5. ^ "The Top 300 of 2021". ClinCalc. Archived from the original on 15 January 2024. Retrieved 14 January 2024.
  6. ^ "Thyroid - Drug Usage Statistics". ClinCalc. Retrieved 14 January 2024.

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