mitochondrial electron transport, cytochrome c to oxygen
ATP synthesis coupled electron transport
positive regulation of hydrogen peroxide biosynthetic process
positive regulation of necrotic cell death
positive regulation of ATP biosynthetic process
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
4513
17709
Ensembl
ENSG00000198712
ENSMUSG00000064354
UniProt
P00403
P00405
RefSeq (mRNA)
n/a
n/a
RefSeq (protein)
n/a
NP_904331
Location (UCSC)
Chr M: 0.01 – 0.01 Mb
Chr M: 0.01 – 0.01 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Location of the MT-CO2 gene in the human mitochondrial genome. MT-CO2 is one of the three cytochrome c oxidase subunit mitochondrial genes (orange boxes).
Cytochrome c oxidase subunit II, transmembrane domain
Bacterial cytochrome c oxidase complex. Subunit II indicated by blue.
Identifiers
Symbol
COX2_TM
Pfam
PF02790
InterPro
IPR011759
PROSITE
PDOC00075
SCOP2
1occ / SCOPe / SUPFAM
TCDB
3.D.4
OPM superfamily
4
OPM protein
1v55
Available protein structures:
Pfam
structures / ECOD
PDB
RCSB PDB; PDBe; PDBj
PDBsum
structure summary
Cytochrome C oxidase subunit II, periplasmic domain
Identifiers
Symbol
COX2
Pfam
PF00116
InterPro
IPR002429
CDD
cd13912
Available protein structures:
Pfam
structures / ECOD
PDB
RCSB PDB; PDBe; PDBj
PDBsum
structure summary
Cytochrome c oxidase II is a protein in eukaryotes that is encoded by the MT-CO2 gene.[5] Cytochrome c oxidase subunit II, abbreviated COXII, COX2, COII, or MT-CO2, is the second subunit of cytochrome c oxidase. It is also one of the three mitochondrial DNA (mtDNA) encoded subunits (MT-CO1, MT-CO2, MT-CO3) of respiratory complex IV.
^ abcGRCh38: Ensembl release 89: ENSG00000198712 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000064354 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Entrez Gene: COX2 cytochrome c oxidase subunit II". This article incorporates text from this source, which is in the public domain.
and 30 Related for: Cytochrome c oxidase subunit 2 information
The enzyme cytochromecoxidase or Complex IV, (was EC 1.9.3.1, now reclassified as a translocase EC 7.1.1.9) is a large transmembrane protein complex...
Cytochromecoxidasesubunit III (COX3) is an enzyme that in humans is encoded by the MT-CO3 gene. It is one of main transmembrane subunits of cytochrome...
Complexes III (Coenzyme Q – Cyt c reductase) and IV (Cyt coxidase). Cytochromec is highly water-soluble, unlike other cytochromes. It is capable of undergoing...
the ND5 gene is terminated by the presence of tRNA-Ser. The cytochromecoxidasesubunit2 gene is of unusual length, with a cox2 encoded protein 446 aa...
III itself is composed of several subunits, one of which is a b-type cytochrome while another one is a c-type cytochrome. Both domains are involved in electron...
coerulea is 18,621 bp in length. Its main characteristic is a cytochromecoxidasesubunit2 gene of unusual length, with a cox2 encoded protein 505 aa in...
SCO2 cytochromecoxidase assembly (also known as SCO2 homolog, mitochondrial and SCO cytochromeoxidase deficient homolog 2) is a protein that in humans...
III (cytochrome bc1 complex; labeled III), which passes them to cytochromec (cyt c). Cyt c passes electrons to Complex IV (cytochromecoxidase; labeled...
catalytic DNA polymerase encoded by the POLG gene and two 55 kDa accessory subunits encoded by the POLG2 gene. The replisome machinery is formed by DNA polymerase...
R, Yoshikawa S (1996). "The whole structure of the 13-subunit oxidized cytochromecoxidase at 2.8 A". Science. 272 (5265): 1136–44. Bibcode:1996Sci.....
enzyme exists as a tetramer of identical subunits, each containing a possible type 2 copper-binding site. Urate oxidase is a homotetrameric enzyme containing...
ATP.[citation needed] Complex IV (EC 1.9.3.1) (also referred to as cytochromecoxidase), is a proton pump driven by electron transport. This enzyme is a...
Phylogeny of the Chipmunk Genus Tamias Based on the Mitochondrial CytochromeOxidaseSubunit II Gene" (PDF). Journal of Mammalian Evolution. 7 (3): 147–166...
muscle, and blood. As a homodimer, sulfite oxidase contains two identical subunits with an N-terminal domain and a C-terminal domain. These two domains are...
NADPH oxidase2 (Nox2), also known as cytochrome b(558) subunit beta or Cytochrome b-245 heavy chain, is a protein that in humans is encoded by the NOX2...
Cytochromecoxidasesubunit 5a is a protein that in humans is encoded by the COX5A gene. Cytochromecoxidase 5A is a subunit of the cytochromec oxidase...
Cytochromecoxidasesubunit 4 isoform 1, mitochondrial (COX4I1) is an enzyme that in humans is encoded by the COX4I1 gene. COX4I1 is a nuclear-encoded...
S2CID 36465802. Cytochrome d ubiquinol oxidasesubunit 1 Borisov VB, Verkhovsky MI (January 2013). "Accommodation of CO in the di-heme active site of cytochrome bd...
Cytochromesc (cyt c, c-type cytochromes) cytochromes, or heme-containing proteins, that have heme C covalently attached to the peptide backbone via one...
Cytochromecoxidasesubunit 7C, mitochondrial is an enzyme that in humans is encoded by the COX7C gene. Cytochromecoxidase (COX), the terminal component...
Global Information
This article incorporates text from this source, which is in the public domain.
