COX6A2 information

COX6A2
Identifiers
Aliases	COX6A2, COX6AH, COXVIAH, cytochrome c oxidase subunit 6A2, MC4DN18, COXVIa-M
External IDs	OMIM: 602009; MGI: 104649; HomoloGene: 38020; GeneCards: COX6A2; OMA:COX6A2 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	31,428,360 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	127,805,559 bp
RNA expression pattern
	Top expressed in
	muscle of thigh; ; apex of heart; ; gastrocnemius muscle; ; right auricle; ; triceps brachii muscle; ; left ventricle; ; glutes; ; thoracic diaphragm; ; biceps brachii; ; Skeletal muscle tissue of biceps brachii;
	Top expressed in
	digastric muscle; ; right ventricle; ; interventricular septum; ; sternocleidomastoid muscle; ; plantaris muscle; ; muscle of thigh; ; extensor digitorum longus muscle; ; soleus muscle; ; temporal muscle; ; triceps brachii muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	cytochrome-c oxidase activity; enzyme regulator activity;
Cellular component	membrane; mitochondrion; mitochondrial inner membrane; mitochondrial respiratory chain complex IV;
Biological process	proton transmembrane transport; generation of precursor metabolites and energy; mitochondrial electron transport, cytochrome c to oxygen; aerobic respiration; regulation of catalytic activity;
	Sources:Amigo / QuickGO
Orthologs
	1339
	12862
	ENSG00000156885
	ENSMUSG00000030785
	Q02221
	P43023
	NM_005205
	NM_009943
	NP_005196
	NP_034073
	Wikidata
View/Edit Human	View/Edit Mouse

Cytochrome c oxidase subunit VIa polypeptide 2 is a protein that in humans is encoded by the COX6A2 gene. Cytochrome c oxidase 6A2 is a subunit of the cytochrome c oxidase complex, also known as Complex IV, the last enzyme in the mitochondrial electron transport chain.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000156885 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000030785 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Cytochrome c oxidase subunit VIa polypeptide 2".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000156885 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000030785 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Cytochrome c oxidase subunit VIa polypeptide 2".

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