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Cold autoimmune hemolytic anemia information


Cold autoimmune hemolytic anemia
SpecialtyHematology


Cold autoimmune hemolytic anemia caused by cold-reacting antibodies. Autoantibodies that bind to the erythrocyte membrane leading to premature erythrocyte destruction (hemolysis) characterize autoimmune hemolytic anemia.

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Autoimmune hemolytic anemia

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Autoimmune hemolytic anemia (AIHA) occurs when antibodies directed against the person's own red blood cells (RBCs) cause them to burst (lyse), leading...

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Cold autoimmune hemolytic anemia

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Cold autoimmune hemolytic anemia caused by cold-reacting antibodies. Autoantibodies that bind to the erythrocyte membrane leading to premature erythrocyte...

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Warm antibody autoimmune hemolytic anemia

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Contrary to cold autoimmune hemolytic anemia (e.g., cold agglutinin disease and paroxysmal cold hemoglobinuria) which happens in cold temperature (28–31 °C)...

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Cold agglutinin disease

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causing them to agglutinate and undergo lysis. It is a form of autoimmune hemolytic anemia, specifically one in which antibodies bind red blood cells only...

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Hemolytic anemia

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pneumoniae infection (cold agglutinin disease) or permanent factors as in autoimmune diseases like autoimmune hemolytic anemia (itself more common in...

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Mixed autoimmune hemolytic anemia

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Mixed autoimmune hemolytic anemia (MAIHA) is a type of autoimmune hemolytic anemia which combines the features of cold sensitive antibody-induced diseases...

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Hemolysis

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, Plasmodium), some autoimmune disorders (e.g., autoimmune haemolytic anaemia, drug-induced hemolytic anemia, atypical hemolytic uremic syndrome (aHUS))...

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Paroxysmal cold hemoglobinuria

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Paroxysmal cold hemoglobinuria (PCH) or Donath–Landsteiner hemolytic anemia (DLHA) is an autoimmune hemolytic anemia featured by complement-mediated intravascular...

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Spherocytosis

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of causes: Warm autoimmune hemolytic anemia Cold autoimmune hemolytic anemia/paroxysmal cold hemoglobinuria Acute and delayed hemolytic transfusion reactions...

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Hemolytic jaundice

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thrombocytopenic purpura, autoimmune hemolytic anemia, hemolysis secondary to drug toxicity, thalassemia minor, and congenital dyserythropoietic anemias. Pathophysiology...

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Acquired hemolytic anemia

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syndrome (antiplatelet antibodies and hemolytic antibodies) Cold antibody autoimmune hemolytic anemia Idiopathic cold hemagglutinin syndrome Infectious mononucleosis...

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Hematologic disease

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(antiplatelet antibodies and hemolytic antibodies) Cold autoimmune hemolytic anemia Cold agglutinin disease Paroxysmal cold hemoglobinuria (rare) Infectious...

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Anemia

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Warm autoimmune hemolytic anemia is caused by autoimmune attack against red blood cells, primarily by IgG. It is the most common of the autoimmune hemolytic...

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Coombs test

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is used to test for autoimmune hemolytic anemia, a condition where the immune system breaks down red blood cells, leading to anemia. The direct Coombs...

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Cold sensitive antibodies

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disease, paroxysmal cold hemoglobinuria in the process of Donath–Landsteiner hemolytic anemia, and vasculitis, respectively. Cold agglutinins are antibodies...

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List of hematologic conditions

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doi:10.1371/journal.pone.0000030. PMC 1762313. PMID 17183658. "Autoimmune Hemolytic Anemia". The Merck Manuals: Online Medical Library. Merck Sharp and...

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Fostamatinib

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trials for rheumatoid arthritis, autoimmune thrombocytopenia, autoimmune hemolytic anemia, IgA nephropathy, and lymphoma. The drug is currently being used...

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Autoimmunity

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chronic and/or recurrent infections many autoimmune diseases including arthritis, autoimmune hemolytic anemia, scleroderma and type 1 diabetes mellitus...

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Red cell agglutination

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This often occurs in cold agglutinin disease, a type of autoimmune hemolytic anemia in which people produce antibodies (termed cold agglutinins) that bind...

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Complete blood count

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cold agglutinins), and the agglutination can be reversed by heating the sample to 37 °C (99 °F). Samples from people with warm autoimmune hemolytic anemia...

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Fifth disease

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miscarriage. In people with sickle-cell disease or other forms of chronic hemolytic anemia such as hereditary spherocytosis, infection can precipitate an aplastic...

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Marginal zone lymphoma

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directed against the patients' own antigens), autoimmune hemolytic anemia, immune thrombocytopenic purpura, cold agglutinins, and/or anticoagulant antibodies...

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Infectious mononucleosis

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directed against red blood cells can lead to a form of autoimmune hemolytic anemia. The cold agglutinin detected is of anti-i specificity. The disease...

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Ii antigen system

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Rupa-Matysek J, Wolny-Rokicka E, Nowakowska E, Gil L (November 2020). "Autoimmune hemolytic anemia: current knowledge and perspectives". Immunity & Ageing. 17 (1):...

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White blood cell

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peripheral circulation can stimulate bone marrow. This can occur in hemolytic anemia and idiopathic thrombocytopenic purpura A normal eosinophil count is...

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Lupus

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flareups); sensitivity = 43%; specificity = 96%. Blood—hematologic disorder—hemolytic anemia (low red blood cell count), leukopenia (white blood cell count<4000/µl)...

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Mycoplasma pneumonia

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atypical pneumonia can be complicated by Stevens–Johnson syndrome, autoimmune hemolytic anemia, cardiovascular diseases, encephalitis, or Guillain–Barré syndrome...

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