CofactorofBRCA1, also known as COBRA1, is a human gene that encodes NELF-B. NELF-B is a subunit of negative elongation factor (NELF), which also includes...
LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activity". J. Biol. Chem. 277 (10): 7849–56...
III) region on chromosome 6. RDBP has been shown to interact with: CofactorofBRCA1, TH1L, and WHSC2. ENSG00000206357, ENSG00000231044, ENSG00000204356...
with initiation factors and cofactors. MED17 has been shown to interact with PPARGC1A, Cyclin-dependent kinase 8 and BRCA1. GRCh38: Ensembl release 89:...
LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activity". J. Biol. Chem. 277 (10): 7849–56...
LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activity". J. Biol. Chem. 277 (10): 7849–56...
LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activity". J. Biol. Chem. 277 (10): 7849–56...
PMID 11839798. Li H, Lee TH, Avraham H (June 2002). "A novel tricomplex ofBRCA1, Nmi, and c-Myc inhibits c-Myc-induced human telomerase reverse transcriptase...
resection, and this step is regulated by numerous factors. In particular, BRCA1 and 53BP1 play a role in determining the balance between the two pathways...
et al. (April 2003). "Negative regulation ofBRCA1 gene expression by HMGA1 proteins accounts for the reduced BRCA1 protein levels in sporadic breast carcinoma"...
subtypes of the cancer. Genetic mutations such as the BRCA1 and BRCA2 have been strongly linked to the development of ovarian cancer. The BRCA1 mutation...
polymerase II apparatus. The mediator of RNA polymerase II transcription subunit 1 protein is a subunit of the CRSP (cofactor required for SP1 activation) complex...
catalyzes the addition of methyl groups to histone H3 at lysine 27, by using the cofactor S-adenosyl-L-methionine. Methylation activity of EZH2 facilitates...
Wei W, Ye L, Young RA, Livingston DM, Parvin JD (May 1997). "BRCA1 is a component of the RNA polymerase II holoenzyme". Proc. Natl. Acad. Sci. U.S.A...
splicing of genes intimately associated with DNA repair. For instance, DNA damages modulate the alternative splicing of the DNA repair genes Brca1 and Ercc1...
subtypes of the cancer. Genetic mutations such as the BRCA1 and BRCA2 have been strongly linked to the development of ovarian cancer. The BRCA1 mutation...
classes of histone deacetylases (classes I, IIA, IIB and IV), which have a different protein fold and use Zn2+ as a cofactor. Sirtuins are a family of signaling...
Wei W, Ye L, Young RA, Livingston DM, Parvin JD (May 1997). "BRCA1 is a component of the RNA polymerase II holoenzyme". Proc. Natl. Acad. Sci. U.S.A...
transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic...
polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is...
protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activity". The Journal of Biological Chemistry. 277 (10):...
DNA-binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. POLR2A has been shown to interact with: BRCA1, CREBBP, CTDP1...
PMID 15989967. Wada O, Oishi H, Takada I, Yanagisawa J, Yano T, Kato S (Aug 2004). "BRCA1 function mediates a TRAP/DRIP complex through direct interaction with TRAP220"...
of RNA polymerase II transcription subunit 21 is an enzyme that in humans is encoded by the MED21 gene. MED21 has been shown to interact with: BRCA1,...
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