BTAF1 information

BTAF1
Identifiers
Aliases	BTAF1, MOT1, TAF(II)170, TAF172, TAFII170, B-TFIID TATA-box binding protein associated factor 1
External IDs	OMIM: 605191; MGI: 2147538; HomoloGene: 31978; GeneCards: BTAF1; OMA:BTAF1 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	92,030,325 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	36,990,152 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; germinal epithelium; ; hair follicle; ; Achilles tendon; ; pancreatic epithelial cell; ; gastric mucosa; ; tibia; ; pancreatic ductal cell; ; sperm; ; skin of abdomen;
	Top expressed in
	hand; ; seminiferous tubule; ; condyle; ; spermatocyte; ; fossa; ; medullary collecting duct; ; primitive streak; ; epidermis; ; abdominal wall; ; hair follicle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; DNA binding; nucleotide binding; hydrolase activity; ATP binding; helicase activity; protein binding;
Cellular component	intracellular membrane-bounded organelle; nucleus; nucleoplasm;
Biological process	negative regulation of transcription, DNA-templated; negative regulation of chromatin binding;
	Sources:Amigo / QuickGO
Orthologs
	9044
	107182
	ENSG00000095564
	ENSMUSG00000040565
	O14981; Q2M1V9
	E9QAE3
	NM_003972
	NM_001080706
	NP_003963; NP_003963.1
	NP_001074175
	Wikidata
View/Edit Human	View/Edit Mouse

TATA-binding protein-associated factor 172 is a protein that in humans is encoded by the BTAF1 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000095564 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000040565 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ van der Knaap JA, Borst JW, van der Vliet PC, Gentz R, Timmers HT (Dec 1997). "Cloning of the cDNA for the TATA-binding protein-associated factorII170 subunit of transcription factor B-TFIID reveals homology to global transcription regulators in yeast and Drosophila". Proc Natl Acad Sci U S A. 94 (22): 11827–32. Bibcode:1997PNAS...9411827V. doi:10.1073/pnas.94.22.11827. PMC 23617. PMID 9342322.
^ Chicca JJ, Auble DT, Pugh BF (Mar 1998). "Cloning and Biochemical Characterization of TAF-172, a Human Homolog of Yeast Mot1". Mol Cell Biol. 18 (3): 1701–10. doi:10.1128/MCB.18.3.1701. PMC 108885. PMID 9488487.
^ "Entrez Gene: BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa (Mot1 homolog, S. cerevisiae)".

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