Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Chalcone is the organic compound C6H5C(O)CH=CHC6H5. It is an α,β-unsaturated ketone. A variety of important biological compounds are known collectively as chalcones or chalconoids.[3] They are widely known bioactive substances, fluorescent materials, and chemical intermediates.
^Merck Index, 11th Edition, 2028
^"Front Matter". Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book). Cambridge: The Royal Society of Chemistry. 2014. p. 722. doi:10.1039/9781849733069-FP001. ISBN 978-0-85404-182-4.
^Tomás-Barberán, Francisco A.; Clifford, Michael N. (2000). "Flavanones, Chalcones and Dihydrochalcones - Nature, Occurrence and Dietary Burden". Journal of the Science of Food and Agriculture. 80 (7): 1073–1080. doi:10.1002/(SICI)1097-0010(20000515)80:7<1073::AID-JSFA568>3.0.CO;2-B.
Chalcone is the organic compound C6H5C(O)CH=CHC6H5. It is an α,β-unsaturated ketone. A variety of important biological compounds are known collectively...
Chalcone synthase or naringenin-chalcone synthase (CHS) is an enzyme ubiquitous to higher plants and belongs to a family of polyketide synthase enzymes...
carboxylate facilitated by 4-Coumarate-CoA ligase, forming (Coumaroyl-CoA). A chalcone synthase then facilitates a series of condensation reactions in the presence...
Naringenin chalcone is a common chalconoid (or chalcone, not to be confused with the compound chalcone). It is synthesized from 4-coumaroyl-CoA and malonyl-CoA...
malonyl CoA followed by aromatization to convert p-coumaroyl-CoA to chalcone. Chalcone isomerase (CHI) then isomerizes the product to close the pyrone ring...
khalkós, "copper", due to its color), also known as chalcones, are natural phenols derived from chalcone. They form the central core for a variety of important...
streams meet and are coupled together by the enzyme chalcone synthase, which forms an intermediate chalcone-like compound via a polyketide folding mechanism...
malonyl-CoA to form naringenin chalcone (tetrahydroxychalcone) through the action of the enzyme chalcone synthase Naringenin chalcone is converted to naringenin...
In enzymology, a chalcone isomerase (EC 5.5.1.6) is an enzyme that catalyzes the chemical reaction a chalcone ⇌ {\displaystyle \rightleftharpoons } a flavanone...
Subsequently, chalcone synthase (CHS) catalyzes the condensation of p-coumaroyl-CoA and three molecules of malonyl-CoA to produce naringenin chalcone, which...
in a series of anti-bacterial chalcones. By modifying certain substituents, the pharmacological activity of the chalcone and its toxicity are also modified...
Cinnamomum mercadoi (kalingag) is a small tree, about 6 to 10 metres (20 to 33 ft) high, with a thick, aromatic bark. The plant part of the family Lauraceae...
Poncirin Sakuranetin Sakuranin Sterubin Pinostrobin The enzyme chalcone isomerase uses a chalcone-like compound to produce a flavanone. Flavanone 4-reductase...
reactions before the final chalcone product is formed. Chalcone synthase (E.C. 2.3.1.74), also known as naringenin-chalcone synthase, is responsible for...
4-hydroxylase. Chalcone synthase then catalyzes the condensation of 4-hydroxycinnamoyl CoA and three molecules of malonyl-CoA to form chalcone. Chalcone is then...
flavonoids, a group of compounds called chalcones, which contain two phenyl rings. Conjugate ring-closure of chalcones results in the familiar form of flavonoids...
pathway. Chalcone synthase, the first enzyme of this pathway, produces chalcone from 4-coumaroyl-CoA. All flavonoids are derived from this chalcone backbone...
Napoli C, Lemieux C, Jorgensen R (April 1990). "Introduction of a Chimeric Chalcone Synthase Gene into Petunia Results in Reversible Co-Suppression of Homologous...
CoA to the carboxylic acid group. The compound reacts with naringenin-chalcone synthase and three malonyl CoA molecules to add six carbon atoms and three...
naringenin chalcone is converted to the isoflavone daidzein by sequential action of three legume-specific enzymes: chalcone reductase, type II chalcone isomerase...
carbon chain elongation with malonyl-CoA and cyclization by chalcone synthase and chalcone isomerase to yield naringenin. Through flavanone 3-hydroxylase...
which enzymes chalcone synthase (CHS) and chalcone reductase (CHR) modify to obtain trihydroxychalcone. CHR is NADPH dependent. Chalcone isomerase (CHI)...
synthase. Tetrahydroxychalcone is then converted into naringenin using chalcone isomerase. Naringenin is converted into eriodictyol using flavanoid 3′-hydroxylase...
has been used to increase the antimicrobial activity of flavanones and chalcones. Usually, alkyl groups are attached to other atoms or groups of atoms...
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