Calponin 2 is a protein that in humans is encoded by the CNN2 gene.
The CNN2 gene is located at 19p13.3 in the human chromosomal genome,[5] encoding the protein calponin 2. Calponin 2 is one of the three isoforms of calponin and an actin filament-associated regulatory protein with wide tissue distributions. Human calponin 2 is a 33.7-kDa protein consisting of 309 amino acids with an isoelectric point (pI) of 7.23. Accordingly, it is also known as neutral calponin.
^ abcGRCh38: Ensembl release 89: ENSG00000064666 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000004665 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Masuda H, Tanaka K, Takagi M, Ohgami K, Sakamaki T, Shibata N, Takahashi K (1996). "Molecular cloning and characterization of human non-smooth muscle calponin". Journal of Biochemistry. 120 (2): 415–24. doi:10.1093/oxfordjournals.jbchem.a021428. PMID 8889829.
human chromosomal genome, encoding the protein calponin2. Calponin2 is one of the three isoforms of calponin and an actin filament-associated regulatory...
Calponin is a calcium binding protein. Calponin tonically inhibits the ATPase activity of myosin in smooth muscle. Phosphorylation of calponin by a protein...
encoding three isoforms of calponin: calponin 1, calponin2, calponin 3, respectively. Protein sequence alignment shows that calponin 1 is highly conserved...
Calponin homology domain (or CH domain) is a family of actin binding domains found in both cytoskeletal proteins and signal transduction proteins. The...
protein important in the formation of filopodia. Fimbrin belongs to the calponin homology (CH) domain superfamily of actin cross-linking proteins. Like...
each of their polypeptide in which each ABD contains two of 125-residue calponin-homology (CH) components. This structure allows for plastins to cross-link...
encoded by the CALD1 gene. Caldesmon is a calmodulin binding protein. Like calponin, caldesmon tonically inhibits the ATPase activity of myosin in smooth muscle...
calmodulin (which takes on the regulatory role in smooth muscle), caldesmon and calponin are significant proteins expressed within smooth muscle. Tropomyosin is...
also related to Calponin, a calcium binding protein. In the 324 to 403 base pair region, there is a Calponin homology domain. Calponin homology domains...
iridophores have been found to contain the smooth muscle regulatory proteins [calponin] and caldesmon. Leaving the neural crest in waves, chromatophores take...
myoepithelial marker proteins such as tumor protein 63, smooth muscle actin, calponin, or CD10. The diagnosis of ICCB tumors is based on the histopathology and...
polymerization. In addition to a CKK domain, CAMSAP2 contains an N-terminal calponin homology domain involved with actin binding. CAMSAP2 proteins are observed...
Biology. 76 (2–3): 313–323. doi:10.1139/bcb-76-2-3-313. PMID 9923700. Gusev NB (October 2001). "Some properties of caldesmon and calponin and the participation...
NEDD9-interacting protein with calponin homology and LIM domains is a protein that in humans is encoded by the MICAL1 gene. MICAL1 has been shown to interact...
attachment to the kinetochore. Endogenous Mps1 is shown to associate with the calponin-homology (CH) domain of Ndc80, which is located in the outer kinetochore...
factor (M-CSF). Certain markers, including CD140a+ , CD140b+ , α-SMA+ and Calponin+, indicate a perivascular origin of this cell line. OP9 cells have been...
R.A., et al. (2015). Mutations in SPECC1L, encoding sperm antigen with calponin homology and coiled-coil domains 1-like, are found in some cases of autosomal...
condensates in the cytosol composed of proteins and RNAs that assemble into 0.1–2 μm membraneless organelles when the cell is under stress. The mRNA molecules...
target proteins to the plasma membrane; Calponin homology (CH) domain, which is an F-actin binding motif; Src homology 2 (SH2) domain, which mediate interaction...
about 50% of cases. Negative: Epithelial membrane antigen, desmin, p63 and calponin. Alcian blue will give a blue staining to the stromal matrix material....
vimentin protein, and collagen type IV protein, but not keratin, S100, calponin, or CD34 proteins. The finding that a tumor's cells have some of these...
Biology. 76 (2–3): 313–323. doi:10.1139/bcb-76-2-3-313. PMID 9923700. Gusev NB (October 2001). "Some properties of caldesmon and calponin and the participation...
Biology. 76 (2–3): 313–323. doi:10.1139/bcb-76-2-3-313. PMID 9923700. Gusev NB (October 2001). "Some properties of caldesmon and calponin and the participation...
invasive cancer measuring up to 1.0 mm in size. Immunohistochemistry for calponin in ductal carcinoma in situ, highlighting myoepithelial cells around all...
all members of the superfamily have. This is made up of two consecutive calponin homology (CH) where spectrin repeats comes right after it. This allows...
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