MICAL1 information

MICAL1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1WYL, 2CO8
Identifiers
Aliases	MICAL1, MICAL, MICAL-1, NICAL, microtubule associated monooxygenase, calponin and LIM domain containing 1
External IDs	OMIM: 607129; MGI: 2385847; HomoloGene: 11246; GeneCards: MICAL1; OMA:MICAL1 - orthologs
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	41,363,028 bp
RNA expression pattern
	Top expressed in
	right coronary artery; ; left coronary artery; ; canal of the cervix; ; spleen; ; left uterine tube; ; popliteal artery; ; ganglionic eminence; ; stromal cell of endometrium; ; right lung; ; ascending aorta;
	Top expressed in
	granulocyte; ; lumbar spinal ganglion; ; ascending aorta; ; external carotid artery; ; intestinal villus; ; internal carotid artery; ; tunica media of zone of aorta; ; fossa; ; Paneth cell; ; sciatic nerve;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	SH3 domain binding; oxidoreductase activity; actin binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; FAD binding; protein binding; metal ion binding; protein kinase binding; monooxygenase activity; NAD(P)H oxidase H2O2-forming activity; actin filament binding;
Cellular component	cytoplasm; cytoskeleton; intermediate filament; hippocampal mossy fiber expansion; cytosol; midbody; intercellular bridge; plasma membrane; actin cytoskeleton;
Biological process	negative regulation of protein phosphorylation; actin filament depolymerization; sulfur oxidation; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of apoptotic process; cytoskeleton organization; signal transduction; regulation of regulated secretory pathway; blood coagulation;
	Sources:Amigo / QuickGO
Orthologs
	64780
	171580
	n/a
	ENSMUSG00000019823
	Q8TDZ2
	Q8VDP3
	NM_022765; NM_001159291; NM_001286613
	NM_001164433; NM_138315; NM_001358838; NM_001358839
	NP_001152763; NP_001273542; NP_073602
	NP_001157905; NP_612188; NP_001345767; NP_001345768
	Wikidata
View/Edit Human	View/Edit Mouse

NEDD9-interacting protein with calponin homology and LIM domains is a protein that in humans is encoded by the MICAL1 gene.^[4]^[5]

^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000019823 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Suzuki T, Nakamoto T, Ogawa S, Seo S, Matsumura T, Tachibana K, Morimoto C, Hirai H (Apr 2002). "MICAL, a novel CasL interacting molecule, associates with vimentin". J Biol Chem. 277 (17): 14933–41. doi:10.1074/jbc.M111842200. PMID 11827972.
^ "Entrez Gene: MICAL1 microtubule associated monoxygenase, calponin and LIM domain containing 1".

[refGRCm38Ensembl-1] GRCm38: Ensembl release 89: ENSMUSG00000019823 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11827972-4] Suzuki T, Nakamoto T, Ogawa S, Seo S, Matsumura T, Tachibana K, Morimoto C, Hirai H (Apr 2002). "MICAL, a novel CasL interacting molecule, associates with vimentin". J Biol Chem. 277 (17): 14933–41. doi:10.1074/jbc.M111842200. PMID 11827972.

[entrez-5] "Entrez Gene: MICAL1 microtubule associated monoxygenase, calponin and LIM domain containing 1".

MICAL1 information

and 6 Related for: MICAL1 information

MICAL1

Monooxygenase

MICAL

Calponin homology domain

RAB1A

NEDD9