Plastin is part of a family of actin-bundling proteins, specifically the α-actinin family of actin-binding protein, which are found in many lifeforms, from humans and other animals to plants and yeasts.[1] These proteins are known to cross-link actin filaments into bundles for various cell purposes.
Plastin structure showing the headpiece, which contains the two EF-hand calcium-binding domains and two actin-binding domains (ABD) with two calponin homology (CH) domains in each ABD group.[2]
Members of plastin include:
LCP1
PLS1
PLS3
^Shinomiya H (2012). "Plastin family of actin-bundling proteins: its functions in leukocytes, neurons, intestines, and cancer". International Journal of Cell Biology. 2012: 213492. doi:10.1155/2012/213492. PMC 3259490. PMID 22262972.
^Morley, Sharon Celeste (November 2013). "The actin-bundling protein L-plastin supports T-cell motility and activation". Immunological Reviews. 256 (1): 48–62. doi:10.1111/imr.12102. PMC 3801223. PMID 24117812.
Plastin is part of a family of actin-bundling proteins, specifically the α-actinin family of actin-binding protein, which are found in many lifeforms...
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