The CD44 antigen is a cell-surface glycoprotein involved in cell–cell interactions, cell adhesion and migration. In humans, the CD44 antigen is encoded by the CD44 gene on chromosome 11.[5] CD44 has been referred to as HCAM (homing cell adhesion molecule), Pgp-1 (phagocytic glycoprotein-1), Hermes antigen, lymphocyte homing receptor, ECM-III, and HUTCH-1.
^ abcGRCh38: Ensembl release 89: ENSG00000026508 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000005087 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Spring FA, Dalchau R, Daniels GL, Mallinson G, Judson PA, Parsons SF, Fabre JW, Anstee DJ (May 1988). "The Ina and Inb blood group antigens are located on a glycoprotein of 80,000 MW (the CDw44 glycoprotein) whose expression is influenced by the In(Lu) gene". Immunology. 64 (1): 37–43. PMC 1385183. PMID 2454887.
The CD44 antigen is a cell-surface glycoprotein involved in cell–cell interactions, cell adhesion and migration. In humans, the CD44 antigen is encoded...
interaction with CD44. Receptor CD44 participates in cell adhesion interactions required by tumor cells. Although hyaluronan binds to receptor CD44, there is...
Both CD44+CD24− and CD44+CD24+ cell populations are tumor initiating cells; however, CSC are most highly enriched using the marker profile CD44+CD49fhiCD133/2hi...
on the presence or absence of inherited antigens that reside within the CD44 molecule that is expressed on the surface of blood cells. It is named so...
proteins. hnRNP has been shown to regulate CD44, a cell-surface glycoprotein, through splicing mechanisms. CD44 is involved in cell-cell interactions and...
neither the CD4 nor CD8 co-receptor. The newly arrived CLP cells are CD4−CD8−CD44+CD25−ckit+ cells, and are termed early thymic progenitor (ETP) cells. These...
cells have to pass the blood–brain barrier (BBB) to form micrometastases. CD44 (a cell-surface transmembrane glycoprotein) is a receptor for hyaluronic...
cleaving high-molecular weight hyaluronic acid, which is mostly bound to the CD44 receptor. The resulting hyaluronic acid fragments of variable size are then...
tumor development. It interacts with a specific transmembrane receptor, CD44. Collagens are the most abundant protein in the ECM. In fact, collagen is...
are likely the precursors of at least some thymocytes. ELPs are Lineage-CD44+CD25-CD117+ and thus closely resemble ETPs, the earliest progenitors in the...
upregulation of CD44, a surface molecule capable of internalizing iron bound to the hyaluronan complex. This alternative pathway, relying on CD44-mediated endocytosis...
transcript abundance and accelerates cell growth. The CD44 3'UTR has been shown to regulate expression of the CD44 protein and cell cycle regulation protein, CDC42...
(CD62L). Central memory T cells also have intermediate to high expression of CD44. This memory subpopulation is commonly found in the lymph nodes and in the...
Chemokine receptor type 7 (CCR7); the absence of the activation markers CD25, CD44 or CD69; and the absence of memory CD45RO isoform. They also express functional...
key proteins have been deemed as markers for BCSCs: CD44, CD24 and aldehyde dehydrogenase (ALDH). CD44, a cell surface glycoprotein, plays a crucial role...
lineages (Lin), but expressing high levels of Sca1 and c-kit; HSC also express CD44, low levels of Thy1.1 (CD90), but no IL-7Ra or CD27.[citation needed] This...
interstitium bind to extracellular matrix proteins via expressed integrins and CD44 to prevent them from leaving the site. A variety of molecules behave as chemoattractants...
glycosaminoglycan, heparan sulfate. Fibronectin has been shown to interact with: CD44 COL7A1, LPA, IGFBP3, TNC, and TRIB3. Fetal fibronectin Fibronectin type I...
that basophils may be defined as the cellular population positive for CD13, CD44, CD54, CD63, CD69, CD107a, CD123, CD164, CD193/ CCR3, CD203c, TLR-4, and...
CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100 CD51 CD52 CD53 CD54 CD55...
isolated from whole blood of people with SLE show reduced expression of CD44 surface molecules involved in the uptake of apoptotic cells. Most of the...
Sindikubwabo F, Cañeque T, Lafon A, Versini A, Lombard B, et al. (October 2020). "CD44 regulates epigenetic plasticity by mediating iron endocytosis". Nature Chemistry...
express the cell surface antigen stage-specific embryonic antigen (SSEA)-1 and CD44 will form an inverted V-shape. They will establish the posterior aspect of...
hyaladherin, a protein capable of binding to hyaluronic acid (HA), homologous to CD44, the main HA receptor. In humans it is encoded by the LYVE1 gene. LYVE1 is...
membrane proteins, such as Notch, ErbB4, E-cadherin, N-cadherin, ephrin-B2, or CD44. The gamma secretase complex consists of four individual proteins: PSEN1...
(CR1 or CD35, immune complex receptor). 1q32.2 023 Indian IN Glycoprotein (CD44 adhesion function?). 11p13 024 Ok OK Glycoprotein (CD147). 19p13.3 025 Raph...
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