BioGRID is a biomedical interaction repository with data compiled through comprehensive curation efforts.
Data types captured
Protein Interactions, Genetic Interactions, Chemical Interactions, Post-Translational Modifications.
Organisms
80
Contact
Research center
Université de Montréal, Princeton University, Mount Sinai Hospital (Toronto)
Laboratory
Institut de Recherche en Immunologie et en Cancérologie, Lewis-Sigler Institute for Integrative Genomics, Lunenfeld-Tanenbaum Research Institute
Authors
Lorrie Boucher, Ashton Breitkreutz, Bobby-Joe Breitkreutz, Christie Chang, Andrew Chatr-Aryamontri, Kara Dolinski, Sven Heinicke, Nadine Kolas, Lara O'Donnell, Sara Oster, Rose Oughtred, Jennifer Rust, Adnane Sellam, Chris Stark, Jean Tang, Chandra Theesfeld, Mike Tyers.
The Biological General Repository for Interaction Datasets (BioGRID) is a curated biological database of protein-protein interactions, genetic interactions, chemical interactions, and post-translational modifications created in 2003 (originally referred to as simply the General Repository for Interaction Datasets (GRID)[2] by Mike Tyers, Bobby-Joe Breitkreutz, and Chris Stark at the Lunenfeld-Tanenbaum Research Institute at Mount Sinai Hospital. It strives to provide a comprehensive curated resource for all major model organism species while attempting to remove redundancy to create a single mapping of data. Users of The BioGRID can search for their protein, chemical or publication of interest and retrieve annotation, as well as curated data as reported, by the primary literature and compiled by in house large-scale curation efforts. The BioGRID is hosted in Toronto, Ontario, Canada and Dallas, Texas, United States and is partnered with the Saccharomyces Genome Database, FlyBase, WormBase, PomBase, and the Alliance of Genome Resources. The BioGRID is funded by the NIH and CIHR. BioGRID is an observer member of the International Molecular Exchange Consortium (IMEx).
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Stark C, Breitkreutz BJ, Reguly T, Boucher L, Breitkreutz A, Tyers M (Jan 2006). "BioGRID: A General Repository for Interaction Datasets". Nucleic Acids Research. 34 (90001): 535–539. doi:10.1093/nar/gkj109. PMC 1347471. PMID 16381927.
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Breitkreutz BJ, Stark C, Tyers M (Jan 2003). "The GRID: the General Repository for Interaction Datasets". Genome Biology. 4 (3): R23. doi:10.1186/gb-2003-4-3-r23. PMC 153463. PMID 12620108.
Tyers M (April 2011). "BioGRID REST Service, BiogridPlugin2 and BioGRID WebGraph: new tools for access to interaction data at BioGRID". Bioinformatics. 27...
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specifically: pombase, flybase, and most InterMine data warehouses, DrugBank, and BioGRID from which its possible to download the protein protein or genetic interactions...
available in a number of primary interaction databases including BIND, BioGRID, CORUM, DIP, HPRD, InnateDB, IntAct, MatrixDB, MINT, MPact, MPIDB, MPPI...
screening has also been performed. Interacting proteins can be found at the BioGRID. Besides the C2H system, a BiFC system has been developed to study protein-protein...
for curating information for BioGRID. Biocuration Hirschman, L.; Yeh, A.; Blaschke, C.; Valencia, A. (2005). "Overview of BioCreAtIvE: Critical assessment...
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(BIND), IntAct, the Molecular Interaction Database (MINT), MIPS, MPact, and BioGRID. The databases of IMEx work together to prevent duplications of effort...
Rust J, Wilbur WJ, Comeau DC, Dolinski K, Tyers M (2017-01-01). "The BioC-BioGRID corpus: full text articles annotated for curation of protein-protein...
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From 2010 to 2020 the companies investments in grid expansion rose from 291.12 BioYuan to 460.5 BioYuan. On October 29, 2014, The Central Commission...
(BIND), IntAct, the Molecular Interaction Database (MINT), MIPS, MPact, and BioGRID. The databases of IMEx work together to prevent duplications of effort...
Oracle Grid Engine, previously known as Sun Grid Engine (SGE), CODINE (Computing in Distributed Networked Environments) or GRD (Global Resource Director)...
shows cytoplasmic positivity in exocrine cells. The IntAct, String, and BioGrid database found eight relevant interacting protein to the TMEM61. Other...
Transduction Knowledge Environment, PID – The Pathway Interaction Database, BioPP – Biological Pathway Publisher. A comprehensive list of resources can be...
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NYU Langone Medical Center, Cold Spring Harbor Laboratory) WikiPathways BioCyc Database Collection: includes EcoCyc and MetaCyc BRENDA: the comprehensive...
supported by the grant provided within the EU projects GeneStream and BioGRID. In the project, the language is used as a rule-based backbone for distributed...
for protein interactions PINV - Protein Interaction Network Visualizer BioGRID database mentha the interactome browser Calderone; et al. (2013). "mentha:...
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