TMEM61 information

TMEM61
Identifiers
Aliases	TMEM61, transmembrane protein 61
External IDs	MGI: 3041156 HomoloGene: 52319 GeneCards: TMEM61
Gene location (Human)
Chr.	Chromosome 1 (human)
End	54,992,288 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	106,397,743 bp
RNA expression pattern
	Top expressed in
	parotid gland; ; anterior pituitary; ; kidney; ; bronchial epithelial cell; ; minor salivary glands; ; seminal vesicula; ; palpebral conjunctiva; ; right adrenal gland; ; secondary oocyte; ; saphenous vein;
	Top expressed in
	stria vascularis; ; hair follicle; ; kidney; ; urinary bladder; ; sciatic nerve; ; renal cortex; ; mouth; ; lip; ; skin of back; ; metanephros;
	More reference expression data
	n/a
Orthologs
	199964
	329909
	ENSG00000143001
	ENSMUSG00000085933
	Q8N0U2
	n/a
	NM_182532
	NM_001370848
	NP_872338
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Transmembrane protein 61 (TMEM61) is a protein that is encoded by the TMEM61 gene in humans. It is located on the first chromosome in humans^[5]and is highly expressed in the intestinal regions predominantly the kidney, adrenal gland and pituitary tissues.^[6] The protein, unlike other transmembrane protein in the region does not promote cancer growth.^[7] However, the TMEM61 protein when inhibited by secondary factors restricts normal activity in the kidney.^[8] The human protein shares many Orthologs and has been prevalent on Earth for millions of years.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000143001 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000085933 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Human hg38 chr1:54,979,264-54,990,924 UCSC Genome Browser v457". genome.ucsc.edu.
^ "GeneCard". GeneCard.
^ Wrzesiński T, Szelag M, Cieślikowski WA, Ida A, Giles R, Zodro E, et al. (July 2015). "Expression of pre-selected TMEMs with predicted ER localization as potential classifiers of ccRCC tumors". BMC Cancer. 15 (1): 518. doi:10.1186/s12885-015-1530-4. PMC 5015219. PMID 26169495.
^ "GDS3626 / ILMN_1667115". www.ncbi.nlm.nih.gov. Retrieved 2023-12-16.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000143001 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000085933 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[:0-5] "Human hg38 chr1:54,979,264-54,990,924 UCSC Genome Browser v457". genome.ucsc.edu.

[6] "GeneCard". GeneCard.

[10.1186_s12885-015-1530-4-7] Wrzesiński T, Szelag M, Cieślikowski WA, Ida A, Giles R, Zodro E, et al. (July 2015). "Expression of pre-selected TMEMs with predicted ER localization as potential classifiers of ccRCC tumors". BMC Cancer. 15 (1): 518. doi:10.1186/s12885-015-1530-4. PMC 5015219. PMID 26169495.

[:1-8] "GDS3626 / ILMN_1667115". www.ncbi.nlm.nih.gov. Retrieved 2023-12-16.