Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Substitution of the heterocycle isoquinoline at the C1 position by a benzyl group provides 1‑benzylisoquinoline, the most widely examined of the numerous benzylisoquinoline structural isomers. The 1-benzylisoquinoline moiety can be identified within numerous compounds of pharmaceutical interest, such as moxaverine; but most notably it is found within the structures of a wide variety of plant natural products, collectively referred to as benzylisoquinoline alkaloids. This class is exemplified in part by the following compounds: papaverine, noscapine, codeine, morphine, apomorphine, berberine, tubocurarine.
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group provides 1‑benzylisoquinoline, the most widely examined of the numerous benzylisoquinoline structural isomers. The 1-benzylisoquinoline moiety can be...
The benzylisoquinoline alkaloids are natural products that can be classified as isoquinoline alkaloids and are derived from benzylisoquinoline. They also...
Narcotine, Nectodon, Nospen, Anarcotine and (archaic) Opiane) is a benzylisoquinoline alkaloid, of the phthalideisoquinoline structural subgroup, which...
Tubocurarine (also known as d-tubocurarine or DTC) is a toxic benzylisoquinoline alkaloid historically known for its use as an arrow poison. In the mid-1900s...
berberine and protopine, among other minor alkaloids. Bloodroot produces benzylisoquinoline alkaloids, primarily the toxin sanguinarine. The alkaloids are transported...
nucifera. The plant also contains nuciferine, neferine, and many other benzylisoquinoline alkaloids with medicinal properties. All parts of Nelumbo nucifera...
Berberine is a quaternary ammonium salt from the protoberberine group of benzylisoquinoline alkaloids, occurring naturally as a secondary metabolite in some plants...
Tetrandrine, a bis-benzylisoquinoline alkaloid, is a calcium channel blocker. It is isolated from the plant Stephania tetrandra, and other Chinese and...
agonist–antagonist drugs have also been developed.[citation needed] Morphine is a benzylisoquinoline alkaloid with two additional ring closures. As Jack DeRuiter of the...
Fumaria officinalis. Protopine is metabolically derived from the benzylisoquinoline alkaloid (S)-Reticuline through a progressive series of five enzymatic...
secondary metabolism, synthesized through the metabolic pathway of benzylisoquinoline. First, the amino acid phenylalanine, through the enzyme phenylalanine...
(S)-Canadine, also known as (S)-tetrahydroberberine and xanthopuccine, is a benzylisoquinoline alkaloid (BIA), of the protoberberine structural subgroup, and is...
eudicotyledons, and also with Buxales and Trochodendrales, are an absence of benzylisoquinoline alkaloids, euAP3 + TM6 genes (gene duplication paleoAP3: Class B)...
chest tightness. (S)-Norcoclaurine/Higenamine is at the center of benzylisoquinoline alkaloid (BIA) biosynthesis. In spite of large structure diversity...
isoquinoline is used to make reference to isoquinoline derivatives. 1-Benzylisoquinoline is the structural backbone in many naturally occurring alkaloids such...
Naloxone Naloxegol The following structures are related to morphinan: Benzylisoquinoline Hasubanan Hasubanonine Brunton L L, Blumenthal D K, Murri N, Dandan...
family Papaveraceae, native to the Caucasus region. It produces the benzylisoquinoline alkaloid armepavine (6 7 methoxy 1 (4' hydroxy benzyl) 1234 tetrahydro...
relationship with norlaudanosoline (tetrahydropapaveroline) or related benzylisoquinoline precursors, which in turn are derived from tyrosine (2). Feeding studies...
occurring chemical compounds from the group of alkaloids. After the benzylisoquinoline alkaloids they are the second largest group of isoquinoline alkaloids...
attributed to opioids. Opiates belong to the large biosynthetic group of benzylisoquinoline alkaloids, and are so named because they are naturally occurring alkaloids...
Annonamine is a benzylisoquinoline alkaloid isolated from Annona muricata (commonly known as soursop, graviola, guanabana, paw-paw and sirsak), a plant...
[better source needed] Typical natural products found in this genus are benzylisoquinoline alkaloids, such as magnoflorine, hernandezine, and the structurally...
Codeine is an opiate and prodrug of morphine mainly used to treat pain, coughing, and diarrhea. It is also commonly used as a recreational drug. It is...
organisms. Phytochemicals in the Lauraceae are numerous and diverse. Benzylisoquinoline alkaloids include aporphines and oxoaporphines, as well as derivatives...
Ocotea fasciculata (also known as Ocotea duckei). It is based on the benzylisoquinoline structure. Reticuline is one of the alkaloids found in opium, and...
been recorded in Menispermum. The family contains a wide range of benzylisoquinoline compounds (alkaloids) and lignans such as furofuran, flavones and...
N-methyltransferase, which modifies a variety of benzylisoquinoline alkaloids including the eponymous alkaloid pavine. Benzylisoquinoline alkaloids like pavine often have...
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