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Autophagy database information


Autophagy Databases
Content
DescriptionDatabases to categorize autophagy-related genes and proteins
Contact
Research centerCenter for Information Biology; DNA Data Bank of Japan, Luxembourg Institute of Health
Primary citationHomma et al.,,[1] Luxembourg Institute of Health [2]
Release date2010
Access
Websitewww.tanpaku.org/autophagy/
Tools
Webautophagy.lu/index.html

Autophagy database(s) aim to provide a comprehensive list of autophagy-related genes and proteins, whether they are identified as orthologs or homologs of other, potentially related, proteins. Many kinds of information, including sequences, functions, and 3D structures, can be stored, thus making them accessible in a searchable format. Information available in a single source, using a searchable format, would simplify work for future researchers. These sources would then help to accomplish this aim by providing recently published references on autophagy alongside categories such as user ratings, a list of informative reviews, and results of an original analysis. As autophagy can play a role in a host of human diseases, such as those of the heart, liver, and kidney, further understanding its mechanisms is essential. Simplifying the research process with some database would then provide a scientific boon.[2]

  1. ^ Cite error: The named reference pmid20972215 was invoked but never defined (see the help page).
  2. ^ a b Cite error: The named reference Human Autophagy was invoked but never defined (see the help page).

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Autophagy database

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Autophagy database(s) aim to provide a comprehensive list of autophagy-related genes and proteins, whether they are identified as orthologs or homologs...

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Autophagy

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Autophagy (or autophagocytosis; from the Ancient Greek αὐτόφαγος, autóphagos, meaning "self-devouring" and κύτος, kýtos, meaning "hollow") is the natural...

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MTOR

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cell proliferation, cell motility, cell survival, protein synthesis, autophagy, and transcription. As a core component of mTORC2, mTOR also functions...

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Abgent

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and disease. Abgent's antibodies target key areas of research including autophagy, neuroscience, cancer, stem cells and more. Abgent was acquired in 2011...

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Zhenyu Yue

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York. He is known for his discovery of genes controlling autophagy (cell self-eating), autophagy functions in central nervous system, molecular mechanism...

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Cell biology

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prevent autophagy, while others utilize autophagy elements for intracellular development or cellular splitting. Macro autophagy, micro autophagy, and chaperon-mediated...

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Spermidine

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theorized to promote autophagy via the MAPK pathway by inhibiting phosphorylation of raf, or possibly by inhibiting cytosolic autophagy-related protein acetylation...

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Lysosome

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endocytosis, while material from the inside of the cell is digested through autophagy. The sizes of the organelles vary greatly—the larger ones can be more...

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Programmed cell death

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of a cell as a result of events inside of a cell, such as apoptosis or autophagy. PCD is carried out in a biological process, which usually confers advantage...

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Cell death

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organism of which the cells are part. Apoptosis or Type I cell-death, and autophagy or Type II cell-death are both forms of programmed cell death, while necrosis...

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Cordyceps

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associated with Alzheimer’s disease with the anti-oxidative stress and autophagy activation. This implication opens up a potential treatment option for...

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Death mask

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necrosis Temporal lobe necrosis Programmed cell death AICD Anoikis Apoptosis Autophagy Intrinsic apoptosis Necroptosis Paraptosis Parthanatos Phenoptosis Pseudoapoptosis...

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Heat shock protein

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afterwards. They are also involved in a special type of autophagy called chaperone-mediated autophagy, when they enable cytosolic proteins to get into lysosomes...

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Reactive oxygen species

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newer line of study has connected ROS levels and autophagy. ROS can also induce cell death through autophagy, which is a self-catabolic process involving...

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Trehalose

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humans, the only known function of trehalose is its ability to activate autophagy inducer.[clarification needed] Trehalose has also been reported for anti-bacterial...

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Longevity

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rapamycin (mTOR), AMP-activating protein kinase (AMPK), and Sirtuin pathways. Autophagy plays a pivotal role in healthspan and lifespan extension. In preindustrial...

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Fasting

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fasting is never necessary and invariably does harm". Tenth of Tevet Autophagy Seventeenth of Tamuz Fast of Gedalia Fast of Esther Tisha B'Av Yom Kippur...

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BioGRID

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biological processes with disease relevance such as chromatin modification, autophagy, and the ubiquitin-proteasome system or diseases of interest including...

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Ashitaba

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natural flavonoid that promotes health through autophagy-dependent and-independent effects. Autophagy, 15(9), 1662-1664. PMID 31248332 PMC 6693465 doi:10...

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ATG9A

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Autophagy-related protein 9A is a protein that in humans is encoded by the ATG9A gene. Functional studies indicate that ATG9A plays a role in autophagy...

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Dengue virus

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such as autophagy and ER stress response, not to mention apoptosis, are triggered depending on the infected cell type. The activation of autophagy and ER...

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Rifampicin

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inhibiting mycolate synthesis) and ambroxol (through host directed effects in autophagy and pharmacokinetics). Rifampicin inhibits bacterial DNA-dependent RNA...

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Cardiotoxicity

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Hayat, M. A. (ed.), "Chapter 10 - Autophagy Upregulation Reduces Doxorubicin-Induced Cardiotoxicity", Autophagy: Cancer, Other Pathologies, Inflammation...

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Metamorphosis

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embryogenesis, and metamorphosis. Additional research in 2019 found that both autophagy and apoptosis, the two ways programmed cell death occur, are processes...

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Alligator

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long enough without a meal during brumation will begin a process called autophagy, where the animal begins to consume its fat reserves to maintain its body...

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Death rattle

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"Interventions for noisy breathing in patients near to death". Cochrane Database of Systematic Reviews (1): CD005177. doi:10.1002/14651858.CD005177.pub2...

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List of natural disasters by death toll

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World Data Service (NGDC/WDS): NCEI/WDS Global Significant Earthquake Database. NOAA National Centers for Environmental Information (1972). "Significant...

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Dignified death

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necrosis Temporal lobe necrosis Programmed cell death AICD Anoikis Apoptosis Autophagy Intrinsic apoptosis Necroptosis Paraptosis Parthanatos Phenoptosis Pseudoapoptosis...

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