Atypical depression is defined in the DSM-IV as depression that shares many of the typical symptoms of major depressive disorder or dysthymia but is characterized by improved mood in response to positive events. In contrast to those with atypical depression, people with melancholic depression generally do not experience an improved mood in response to normally pleasurable events. Atypical depression also often features significant weight gain or an increased appetite, hypersomnia, a heavy sensation in the limbs, and interpersonal rejection sensitivity that results in significant social or occupational impairment.[4]
Despite its name, "atypical" depression does not mean it is uncommon or unusual.[5] The reason for its name is twofold: it was identified with its "unique" symptoms subsequent to the identification of melancholic depression and its responses to the two different classes of antidepressants that were available at the time were different from melancholic depression (i.e., MAOIs had clinically significant benefits for atypical depression, while tricyclics did not).[6]
Atypical depression is four times more common in females than in males.[7] Individuals with features of atypical depression tend to report an earlier age of onset (e.g. while in high school) of their depressive episodes. These episodes tend to be more chronic than those of major depressive disorder[2] and only have partial remission between episodes. Younger individuals may be more likely to have atypical features, whereas older individuals may more often have episodes with melancholic features.[4] Atypical depression has high comorbidity with anxiety disorders, carries more risk of suicidal behavior, and has distinct personality psychopathology and biological traits.[2] Atypical depression is more common in individuals with bipolar I,[2] bipolar II,[2][8] cyclothymia[2] or seasonal affective disorder.[4] Depressive episodes in bipolar disorder tend to have atypical features,[2] as does depression with seasonal patterns.[9]
^ abDavidson JR, Miller RD, Turnbull CD, Sullivan JL (May 1982). "Atypical depression". Archives of General Psychiatry. 39 (5): 527–534. doi:10.1001/archpsyc.1982.04290050015005. PMID 7092486.
^ abcdefgSingh T, Williams K (April 2006). "Atypical depression". Psychiatry. 3 (4): 33–39. PMC 2990566. PMID 21103169.
^Thase ME (2007). "Recognition and diagnosis of atypical depression". The Journal of Clinical Psychiatry. 68 (Suppl 8): 11–16. PMID 17640153.
^ abcAmerican Psychiatric Association. (2000). Mood Disorders. In Diagnostic and Statistical Manual of Mental Disorders (4th ed., text rev.) Washington, DC: Author.[page needed]
^"Atypical depression". Mayo Clinic. Retrieved 2013-06-23.
^Cristancho M (2012-11-20). "Atypical Depression in the 21st Century: Diagnostic and Treatment Issues". Psychiatric Times. Psychiatric Times Vol 28 No 1. 28 (1). Archived from the original on 2013-12-02. Retrieved 23 November 2013.
^Łojko D, Rybakowski JK (2017). "Atypical depression: current perspectives". Neuropsychiatric Disease and Treatment. 13: 2447–2456. doi:10.2147/NDT.S147317. PMC 5614762. PMID 29033570.
^Perugi G, Akiskal HS, Lattanzi L, Cecconi D, Mastrocinque C, Patronelli A, et al. (1998). "The high prevalence of "soft" bipolar (II) features in atypical depression". Comprehensive Psychiatry. 39 (2): 63–71. doi:10.1016/S0010-440X(98)90080-3. PMID 9515190.
^Juruena MF, Cleare AJ (May 2007). "[Overlap between atypical depression, seasonal affective disorder and chronic fatigue syndrome]" [Overlap between atypical depression, seasonal affective disorder and chronic fatigue syndrome]. Revista Brasileira de Psiquiatria (in Portuguese). 29 (Suppl 1): S19–S26. doi:10.1590/S1516-44462007000500005. PMID 17546343.
and 27 Related for: Atypical depression information
Atypicaldepression is defined in the DSM-IV as depression that shares many of the typical symptoms of major depressive disorder or dysthymia but is characterized...
effective antidepressants, especially for treatment-resistant depression and atypicaldepression. They are also used to treat panic disorder, social anxiety...
cause depression in healthy persons, that antidepressants instantly increase levels of monoamines but take weeks to work, and the existence of atypical antidepressants...
An atypical antidepressant is any antidepressant medication that acts in a manner that is different from that of most other antidepressants. Atypical antidepressants...
a decreased or absent ability to experience a sense of pleasure Atypicaldepression Blunted affect, a symptom of PTSD, schizophrenia, and ASPD involving...
Patterns and Treatment Outcome in Patients with Melancholic, Atypical and Non-Melancholic Depressions". PLOS ONE. 7 (10): e48200. Bibcode:2012PLoSO...748200G...
Atypical is an American comedy-drama television series created by Robia Rashid for Netflix. The series takes place in Connecticut, and focuses on the life...
of depression, and Nettle gives this as the explanation for the existence of depression rather than hypothesizing, as others have, that depression itself...
disorder are stress response syndrome (new name as of 2013) and situational depression since it is one of the most common symptoms. Some emotional signs of adjustment...
The Atypical Family (Korean: 히어로는 아닙니다만) is an ongoing South Korean television series starring Jang Ki-yong, Chun Woo-hee, Go Doo-shim and Claudia Kim...
of atypicaldepression. However, there have been studies claiming that these symptoms alone are sufficient to diagnose the condition of atypical depression...
depression with atypical features, which is seen in the above table, is not a rare form of depression. The cortisol profile in atypicaldepression, in...
Postpartum depression has been known to be called many different names such as the following: Postpartum blues, baby blues, and maternity blues. This is...
lithium and anticonvulsants for this purpose. Atypical antipsychotics are also indicated for bipolar depression refractory to treatment with mood stabilizers...
published in 1994. The book describes the author's experiences with atypicaldepression, her own character failings and how she managed to live through particularly...
sensation-related disorders, cyclothymia has also been associated with atypicaldepression. In one study, a connection was found between interpersonal sensitivity...
Masked depression (MD) was a proposed form of atypicaldepression in which somatic symptoms or behavioural disturbances dominate the clinical picture and...
disorder. The diagnosis of agoraphobia has been shown to be comorbid with depression, substance abuse, and suicide ideation. Without treatment, it is uncommon...
Psychiatric Association recognized the disorder, while categorizing it as an atypical somatoform disorder, in the third edition of its Diagnostic and Statistical...
were thoughts about family, financial, and work stressors or feelings of depression. "Maintaining" cognitions provided additional reinforcement for stealing...
surrounding stimuli. Although mania is often conceived as a "mirror image" to depression, the heightened mood can be either euphoric or dysphoric. As the mania...
(1991). Constructivist Perspectives on Developmental Psychopathology and Atypical Development. Lawrence Erlbaum. Maddux, J E et al. (2005). Psychopathology:...
and treatment failures. The most common presenting complaint of DID is depression, with headaches being a common neurological symptom. Comorbid disorders...
Antidepressants. Management of depressionDepression in childhood and adolescence Antidepressants in Japan Atypical antidepressant Depression and natural therapies...
potentially worsened. Also using promethazine may be useful. Recently, three atypical antipsychotics, olanzapine, aripiprazole and ziprasidone, have become available...