Blood serum containing antibodies; used to spread passive immunity
This article is about the applications of antiserum. For an explanation of its production, see polyclonal antibodies.
This article may require cleanup to meet Wikipedia's quality standards. The specific problem is: Dives too deep into monoclonal, which mostly isn’t produced by live humans (or domestic animals) donating their serum, even in "modern use"! Antiserum needs to be serum or derived from it. Please help improve this article if you can.(January 2023) (Learn how and when to remove this message)
In immunology, antiserum is a blood serum containing antibodies (either monoclonal or polyclonal) that is used to spread passive immunity to many diseases via blood donation (plasmapheresis). For example, convalescent serum, passive antibody transfusion from a previous human survivor, used to be the only known effective treatment for ebola infection with a high success rate of 7 out of 8 patients surviving.[1]
Antisera are widely used in diagnostic virology laboratories. The most common use of antiserum in humans is as antitoxin or antivenom to treat envenomation.[citation needed]
Serum therapy, also known as serotherapy, describes the treatment of infectious disease using the serum of animals that have been immunized against the specific organisms or their product, to which the disease is supposedly referable.[citation needed]
^Mupapa, K; Massamba, M; Kibadi, K; Kuvula, K; Bwaka, A; Kipasa, M; Colebunders, R; Muyembe-Tamfum, JJ (1999). "Treatment of Ebola Hemorrhagic Fever with Blood Transfusions from Convalescent Patients". The Journal of Infectious Diseases. 179 Suppl 1 (179): S18–S23. doi:10.1086/514298. PMID 9988160.
In immunology, antiserum is a blood serum containing antibodies (either monoclonal or polyclonal) that is used to spread passive immunity to many diseases...
Serum sickness in humans is a reaction to proteins in antiserum derived from a non-human animal source, occurring 5–10 days after exposure. Symptoms often...
(1993). "Human basophil degranulation is not triggered by very dilute antiserum against human IgE". Nature. 366 (6455): 525–27. Bibcode:1993Natur.366...
Antivenom, also known as antivenin, venom antiserum, and antivenom immunoglobulin, is a specific treatment for envenomation. It is composed of antibodies...
cautiously to avoid fueling the constant consumptive coagulopathy. An antiserum is produced by the Butantan Institute in São Paulo, Brazil. It effectively...
addition of an antiserum. By using a standard amount of virus, a standard amount of blood cells, and serially diluting the antiserum, one can identify...
Serum (blood), plasma from which the clotting proteins have been removed Antiserum, blood serum with specific antibodies for passive immunity Serous fluid...
bullet. He also made a decisive contribution to the development of an antiserum to combat diphtheria and conceived a method for standardizing therapeutic...
Vaccination Jim (horse) Antiserum "Report of the Lancet special commission on the relative strengths of diphtheria antitoxic antiserums". Lancet. 148 (3803):...
immune factors: antibody therapy by whole serum: serotherapy, including antiserum therapy by immunoglobulins: immunoglobulin therapy by monoclonal antibodies:...
also kept for more specialised purposes, such as to produce vaccines and antiserum (containing antibodies) for medical use. Where fodder or other crops are...
venom, used by Pakistani old medicine. It is proved to be better than antiserum, the paste of this plant's leaves are applied topically on the cobra bite...
antibodies that bind to the same antigen—in the serum, which can now be called antiserum. Antigens are also injected into chickens for generation of polyclonal...
denote lower strengths of diphtheria and pertussis vaccines. Tetanus antiserum was developed in 1890, with its protective effects lasting a few weeks...
antibody preparations, known as CroFab and in Digibind, a similar sheep antiserum fragment, used to neutralize the cardiac medication digoxin in acute overdose...
drug therapies. His laboratory made decisive contributions to developing antiserum for diphtheria and standardizing therapeutic serums. Early examples of...
used for prophylaxis and treatment. In World War I, injection of tetanus antiserum from horses was widely used as a prophylaxis against tetanus in wounded...
(30 June 1988). "Human basophil degranulation triggered by very dilute antiserum against IgE". Nature. 333 (6176): 816–818. Bibcode:1988Natur.333..816D...
gradually increasing dose of diphtheria in animals stimulated production of antiserum. One well known example of a bioassay is the "canary in the coal mine"...
Australian Red Back Spider (Latrodectus Hasseltii): I. Preparation of Antiserum by the Use of Venom Adsorbed on Aluminium Phosphate". The Medical Journal...
Mortality from meningitis was very high (over 90%) in early reports. In 1906, antiserum was produced in horses; this was developed further by the American scientist...
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