Antibody with the ability to neutralize a specific toxin
For bacterially-produced antitoxins, see toxin-antitoxin system.
A vintage 1895 vial of diphtheria antitoxin.
An antitoxin is an antibody with the ability to neutralize a specific toxin. Antitoxins are produced by certain animals, plants, and bacteria in response to toxin exposure. Although they are most effective in neutralizing toxins, they can also kill bacteria and other microorganisms. Antitoxins are made within organisms, and can be injected into other organisms, including humans, to treat an infectious disease. This procedure involves injecting an animal with a safe amount of a particular toxin. The animal's body then makes the antitoxin needed to neutralize the toxin. Later, blood is withdrawn from the animal. When the antitoxin is obtained from the blood, it is purified and injected into a human or other animal, inducing temporary passive immunity. To prevent serum sickness, it is often best to use an antitoxin obtained from the same species (e.g. use human antitoxin to treat humans).
Most antitoxin preparations are prepared from donors with high titers of antibody against the toxin, making them hyperimmune globulins.
An antitoxin is an antibody with the ability to neutralize a specific toxin. Antitoxins are produced by certain animals, plants, and bacteria in response...
honey should not be fed to children under 12 months. Treatment is with an antitoxin. In those who lose their ability to breathe on their own, mechanical ventilation...
Diphtheria antitoxin (DAT) is a medication made up of antibodies used in the treatment of diphtheria. It is no longer recommended for prevention of diphtheria...
recommended every ten years. Protection can be verified by measuring the antitoxin level in the blood. Diphtheria can be prevented in those exposed, as well...
The Botulism Antitoxin Heptavalent (A, B, C, D, E, F, G) - (Equine) (trade name BAT), made by Emergent BioSolutions Canada Inc. (formerly Cangene Corporation)...
1890 discovery of an antitoxin-based immunity to diphtheria and tetanus by Emil Adolf von Behring and Kitasato Shibasaburō, antitoxin became the first major...
modules are toxin-antitoxin systems. Each consists of a pair of genes that specify two components: a stable toxin and an unstable antitoxin that interferes...
the first one awarded in that field, for his discovery of a diphtheria antitoxin. He was widely known as a "saviour of children", as diphtheria used to...
Great Race of Mercy and The Serum Run, was a transport of diphtheria antitoxin by dog sled relay across the US territory of Alaska by 20 mushers and...
antisense RNA antitoxin that overlaps 2 toxins: 3' end of yonT and yoyJ at its 5'end. In type I toxin-antitoxin (TA) systems the antitoxin is a small RNA...
using a blood test and a urine test. It may be prevented by not using an antitoxin derived from animal serum, and through prophylactic antihistamines or...
form type I toxin/antitoxin system that includes an mRNA encoding for a short, toxic peptide (bsrE, bsrG and bsrH ) and an antitoxin that consists of an...
Kaasen on the final leg of the 1925 serum run to Nome, in which diphtheria antitoxin was transported from Anchorage, Alaska, to Nenana, Alaska, by train and...
by Dr. John G. FitzGerald in 1914 in Toronto to produce the diphtheria antitoxin. Contemporaneously, the institution was likened to the Pasteur Institutes...
without tetanus immunoglobulin (also called tetanus antibodies or tetanus antitoxin). It can be given as intravenous therapy or by intramuscular injection...
Digoxin immune fab or digoxin-specific antibody is an antidote for overdose of digoxin. It is made from immunoglobulin fragments from sheep that have already...
In molecular biology, the epsilon antitoxin, produced by various prokaryotes, forms part of a post-segregational killing system, which is involved in...
with antibiotics and possibly antitoxin. The type and number of antibiotics used depend on the type of infection. Antitoxin is recommended for those with...
diphtheria antitoxin (antibodies against diphtheria toxin). Jim produced over 30 US quarts (7.5 US gallons; 28.5 litres) of diphtheria antitoxin in his career...
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