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Papain information


Papain family cysteine protease
Papain from Carica papaya
Identifiers
SymbolPeptidase_C1
PfamPF00112
InterProIPR000668
PROSITEPDOC00126
SCOP21aec / SCOPe / SUPFAM
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary
papain
Identifiers
EC no.3.4.22.2
CAS no.9001-73-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

Papain, also known as papaya proteinase I, is a cysteine protease (EC 3.4.22.2) enzyme present in papaya (Carica papaya) and mountain papaya (Vasconcellea cundinamarcensis). It is the namesake member of the papain-like protease family.

It has wide ranging commercial applications in the leather, cosmetic, textiles, detergents, food and pharmaceutical industries. In the food industry, papain is used as an active ingredient in many commercial meat tenderizers.[1]

  1. ^ Islam MN, Molinar-Toribio EM (July–December 2013). "Development of a meat tenderizer based on papaya peel. Observación por Pares Basada en Mapas Conceptuales: Una Estrategia para Fomentar el "Scholarship of Teaching and Learning" en la Universidad Tecnológica de Panamá. 2013;24" (PDF). RIDTEC. 9 (2).

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Papain

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Papain, also known as papaya proteinase I, is a cysteine protease (EC 3.4.22.2) enzyme present in papaya (Carica papaya) and mountain papaya (Vasconcellea...

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Papaya

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also contain the cyanogenic substance prunasin. The green fruit contains papain, a cysteine protease enzyme used to tenderize meat (see below). Native to...

Word Count : 3801

Bromelain

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exposure to the digestive enzyme trypsin have little effect on it. Along with papain, bromelain is one of the most popular proteases to use for meat tenderizing...

Word Count : 1358

PLP

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Look up PLP in Wiktionary, the free dictionary. PLP may refer to: Papain-like protease, a family of cysteine protease enzymes Phantom limb pain, pain felt...

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Cysteine protease

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1873, the first cysteine protease to be isolated and characterized was papain, obtained from Carica papaya. Cysteine proteases are commonly encountered...

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Crotalidae polyvalent immune Fab

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monospecific antivenin is purified from sheep serum, digested with the enzyme papain, and purified further, resulting in specific Fab fragments. The resulting...

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Anthelmintic

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Anthelmintic effect of papain on Heligmosomoides bakeri...

Word Count : 1918

Tofu

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that have been shown to produce tofu are papain, and alkaline and neutral proteases from microorganisms. Papain, moreover, has been studied as a gelling...

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Debridement

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Clostridium histolyticum; or from plants, examples include collagenase, varidase, papain, and bromelain. Some of these enzymatic debriders are selective, while some...

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Nematode

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Anthelmintic effect of papain on Heligmosomoides bakeri...

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Fragment crystallizable region

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An antibody digested by papain yields three fragments, two Fab fragments and one Fc fragment...

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Jain Irrigation Systems

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the production of papain from papaya latex. In December 1978, the founder traveled to New York in search of customers for Jain papain. The competition...

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Enzyme

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Increase fermentation efficiency by reducing diacetyl formation. Culinary uses Papain Tenderize meat for cooking. Dairy industry Rennin Hydrolyze protein in the...

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Convergent evolution

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organisation of acid-base-nucleophile in different protease superfamilies. Shown are the triads of subtilisin, prolyl oligopeptidase, TEV protease, and papain....

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Mountain papaya

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strong and fruity, due to the complex volatile compounds in the flesh. The papain enzyme present in the milky latex of immature fruits and leaves is often...

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Actinidain

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banana, figs, and papaya. This enzyme is part of the peptidase C1 family of papain-like proteases. As a known allergen in kiwifruit, the enzyme is under preliminary...

Word Count : 1922

Beef

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disrupt the proteins. Also, solutions of exogenous proteolytic enzymes (papain, bromelin or ficin) can be injected to augment the endogenous enzymes. Similarly...

Word Count : 8115

Protease

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bonds of a protein (endopeptidases, such as trypsin, chymotrypsin, pepsin, papain, elastase). Catalysis is achieved by one of two mechanisms: Aspartic, glutamic...

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Ryan Corr

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tragic love story with wide appeal". Herald Sun. Retrieved 14 February 2016. Papain, Jessie (28 September 2015). "Peacocke at home in Wanted role". The West...

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Cosmetics

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malic acid, mandelic acid, glycolic acid, lactic acid, salicylic acid, papain, and bromelain. They may be found in cleansers, scrubs, and peels, but also...

Word Count : 10128

Pepsin

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peptides. Fab fragments are generated by cleavage of IgG with papain instead of pepsin. Papain cleaves IgG above the hinge region containing the disulfide...

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Iodine

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12 December 2008. Polgár L (August 1979). "Deuterium isotope effects on papain acylation. Evidence for lack of general base catalysis and for enzyme--leaving-group...

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Caricaceae

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herbs. Some species, such as the papaya, bear edible fruit and produce papain. Based on molecular analyses, this family has been proposed to have originated...

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E number

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Amylase stabiliser, flavour enhancer E1101 Proteases ((i)Protease, (ii)Papain, (iii)Bromelain, (iv)Ficin) stabiliser, flavour enhancer E1102 Glucose oxidase...

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Zingibain

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ginger protease I (GP-I) and ginger protease II (GP-II). As a member of the papain-like protease family of cysteine proteases, zingibain shares several structural...

Word Count : 1872

Soy protein

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trypsin inhibitors, hemagglutinins, and cysteine proteases very similar to papain. The soy cotyledon storage proteins, important for human nutrition, can...

Word Count : 4009

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