Anion exchange protein 3 is a membrane transport protein that in humans is encoded by the SLC4A3 gene.[5][6] AE3 is functionally similar to the Band 3 Cl−/HCO3− exchange protein but it is expressed primarily in brain neurons and in the heart. Like AE2 its activity is sensitive to pH.[7][8] AE3 mutations have been linked to seizures.[9][10]
^ abcGRCh38: Ensembl release 89: ENSG00000114923 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000006576 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Su YR, Klanke CA, Houseal TW, Linn SC, Burk SE, Varvil TS, Otterud BE, Shull GE, Leppert MF, Menon AG (Jan 1995). "Molecular cloning and physical and genetic mapping of the human anion exchanger isoform 3 (SLC2C) gene to chromosome 2q36". Genomics. 22 (3): 605–9. doi:10.1006/geno.1994.1433. PMID 8001971.
^"Entrez Gene: SLC4A3 solute carrier family 4, anion exchanger, member 3".
^Casey JR, Sly WS, Shah GN, Alvarez BV (November 2009). "Bicarbonate homeostasis in excitable tissues: role of AE3 Cl-/HCO3- exchanger and carbonic anhydrase XIV interaction". Am. J. Physiol., Cell Physiol. 297 (5): C1091–102. doi:10.1152/ajpcell.00177.2009. PMC 2777400. PMID 19692653.
^Hayashi H, Suruga K, Yamashita Y (June 2009). "Regulation of intestinal Cl-/HCO3- exchanger SLC26A3 by intracellular pH". Am. J. Physiol., Cell Physiol. 296 (6): C1279–90. doi:10.1152/ajpcell.00638.2008. PMID 19321737.
^Hentschke M, Wiemann M, Hentschke S, Kurth I, Hermans-Borgmeyer I, Seidenbecher T, Jentsch TJ, Gal A, Hübner CA (January 2006). "Mice with a targeted disruption of the Cl-/HCO3- exchanger AE3 display a reduced seizure threshold". Mol. Cell. Biol. 26 (1): 182–91. doi:10.1128/MCB.26.1.182-191.2006. PMC 1317631. PMID 16354689.
^Vilas GL, Johnson DE, Freund P, Casey JR (September 2009). "Characterization of an epilepsy-associated variant of the human Cl-/HCO3(-) exchanger AE3". Am. J. Physiol., Cell Physiol. 297 (3): C526–36. doi:10.1152/ajpcell.00572.2008. PMID 19605733. S2CID 29802528.
and 25 Related for: Anion exchange protein 3 information
Anionexchangeprotein3 is a membrane transport protein that in humans is encoded by the SLC4A3 gene. AE3 is functionally similar to the Band 3 Cl−/HCO3−...
Band 3anion transport protein, also known as anionexchanger 1 (AE1) or band 3 or solute carrier family 4 member 1 (SLC4A1), is a protein that is encoded...
Anionexchangeprotein 2 (AE2) is a membrane transport protein that in humans is encoded by the SLC4A2 gene. AE2 is functionally similar to the Band 3...
either cation exchangers, which exchange positively charged ions (cations), or anionexchangers, which exchange negatively charged ions (anions). There are...
the isoelectric point of a protein. The two types of ion chromatography are anion-exchange and cation-exchange. Cation-exchange chromatography is used when...
transport of anions across cellular barriers, although their functions may vary. All of them exchange bicarbonate. Characterized protein members of the...
Chloride anionexchanger, also known as down-regulated in adenoma (protein DRA), is a protein that in humans is encoded by the SLC26A3 gene. Protein DRA is...
Anionexchange transporter is a protein that in humans is encoded by the SLC26A7 gene. This gene is one member of a family of sulfate/anion transporter...
Members of the Organo Anion Transporter (OAT) Family (organic-anion-transporting polypeptides, OATP) are membrane transport proteins or 'transporters' that...
The organic anion transporter 1 (OAT1) also known as solute carrier family 22 member 6 (SLC22A6) is a protein that in humans is encoded by the SLC22A6...
antiporter is anionexchanger 1 (AE1), which is also known as band 3anion transport protein or solute carrier family 4 member 1 (SLC4A1). This exchanger is found...
Pendrin is an anionexchangeprotein that in humans is encoded by the SLC26A4 gene (solute carrier family 26, member 4). Pendrin was initially identified...
is important. They found Ca2+ ions are involved in anion channel activation, which allows for anions to flow into the guard cell. They also are involved...
charge. Anionexchange resins have a positive charge and are used to retain and separate negatively charged compounds (anions), while cation exchange resins...
proper cell volume. These channels conduct Cl− or other anions such as HCO−3, I−, SCN−, and NO−3. The structure of these channels are not like other known...
values, the net charge of most proteins is negative, where they bind to the positively-charged matrix in anionexchangers. When the environment is at a...
Solute carrier family 22 member 8, or organic anion transporter 3 (OAT3), is a protein that in humans is encoded by the SLC22A8 gene. OAT3 is involved...
Solute carrier organic anion transporter family member 1B1 is a protein that in humans is encoded by the SLCO1B1 gene. Pharmacogenomic research indicates...
anionic precursors such as chloride but includes ligands where salts of anion do not really exist such as hydride and alkyl. Especially in the area of...
English) is a compound containing a R−S−S−R′ functional group or the S2− 2 anion. The linkage is also called an SS-bond or sometimes a disulfide bridge and...
strong-anionexchange-mediated phosphoproteomics". bioRxiv 10.1101/202820. Functional analyses for site-specific phosphorylation of a target protein in cells...
Prestin is a protein that is critical to sensitive hearing in mammals. It is encoded by the SLC26A5 (solute carrier anion transporter family 26, member...
fibrosis transmembrane conductance regulator (CFTR) is a membrane protein and anion channel in vertebrates that is encoded by the CFTR gene. Geneticist...
Global Information
