Alternative Splicing and Transcript Diversity database information
2008–2012 European database of transcript variants
ASTD
Content
Description
Alternative splicing and transcript diversity database
Contact
Research center
European Bioinformatics Institute
Authors
Gautier Koscielny
Primary citation
Koscielny & al. (2009)[1]
Release date
2008
Access
Website
ebi.ac.uk/astd (archive)
The Alternative Splicing and Transcript Diversity database (ASTD) was a database of transcript variants maintained by the European Bioinformatics Institute from 2008 to 2012.[2] It contained transcription initiation, polyadenylation and splicing variant data.[1]
The AlternativeSplicingandTranscriptDiversitydatabase (ASTD) was a database of transcript variants maintained by the European Bioinformatics Institute...
Alternativesplicing, or alternative RNA splicing, or differential splicing, is an alternativesplicing process during gene expression that allows a single...
Institute of Genomics, Chinese Academy of Sciences Alternativesplicingandtranscriptdiversitydatabase BioSamples European Molecular Biology Organization...
transcriptome, the sum of all of its RNA transcripts. The information content of an organism is recorded in the DNA of its genome and expressed through transcription...
transcripts, such as alternativesplicing. Since a genome contains the sum of all introns and exons that may be present in a transcript, spliced variants that...
alternative splicing compared to genes that code a single isoform. This is because alternativelyspliced mRNAs are enriched in METTL3 binding sites. Splicing is...
tRNA precursors, and are removed by a tRNA splicing endonuclease. The exons are then linked together by a second protein, the tRNA splicing ligase. Note that...
analysis); mapping each probe to the mRNA transcript that it measures (Annotation); the sheer volume of data and the ability to share it (Data warehousing)...
In addition, RBM10 primary transcripts are subjected to alternativesplicing at several exons by unidentified splicing regulators, leading to the generation...
three other transcripts encode isoform b, c, and d, respectively. The table below is representative of these transcripts. Alternatively, when the primary...
determined. Alternativesplicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. Splice variants...
This so-called alternativesplicing creates series of different transcripts originating from a single gene. Because these transcripts can be potentially...
receptor that in humans is encoded by the CHRM2 gene. Multiple alternativelysplicedtranscript variants have been described for this gene. It is Gi-coupled...
cardiomyopathy as well as with restrictive and dilated cardiomyopathy. Transcripts for this gene undergo alternativesplicing that results in many tissue-specific...
single large mRNAs, alternativesplicing enables a single genomic region to encode multiple district products and trans-splicing concatenates mRNAs from...
their start and stop codons, UTRs andalternativetranscripts, and ideally should include information about the sequence alignments and gene predictions...
now thought that this sequence represents a transcript variant of CYP3A4. Alternatively-splicedtranscript variants encoding different isoforms have been...
strand of the long arm of chromosome 10. Its 26 alternativelyspliced exons encode 5 potential transcript variants, the largest of which being 4101 base...
phases: an early and a late phase. In both phases, a primary transcript that is alternativelyspliced to generate monocistronic mRNAs compatible with the host's...
tropomyosin in human fibroblasts: evidence for expression by an alternative RNA splicing mechanism". Proc. Natl. Acad. Sci. U.S.A. 82 (23): 7835–9. doi:10...