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Alternative Splicing and Transcript Diversity database information


ASTD
Content
DescriptionAlternative splicing and transcript diversity database
Contact
Research centerEuropean Bioinformatics Institute
AuthorsGautier Koscielny
Primary citationKoscielny & al. (2009)[1]
Release date2008
Access
Websiteebi.ac.uk/astd (archive)

The Alternative Splicing and Transcript Diversity database (ASTD) was a database of transcript variants maintained by the European Bioinformatics Institute from 2008 to 2012.[2] It contained transcription initiation, polyadenylation and splicing variant data.[1]

  1. ^ a b Koscielny, Gautier; Le Texier, Vincent; Gopalakrishnan, Chellappa; Kumanduri, Vasudev; Riethoven, Jean-Jack; Nardone, Francesco; Stanley, Eleanor; Fallsehr, Christine; Hofmann, Oliver; Kull, Meelis; Harrington, Eoghan; Boué, Stéphanie; Eyras, Eduardo; Plass, Mireya; Lopez, Fabrice; Ritchie, William; Moucadel, Virginie; Ara, Takeshi; Pospisil, Heike; Herrmann, Alexander; Reich, Jens G; Guigó, Roderic; Bork, Peer; von Knebel Doeberitz, Magnus; Vilo, Jaak; Hide, Winston; Apweiler, Rolf; Thanaraj, Thangavel Alphonse; Gautheret, Daniel (Mar 2009). "ASTD: The Alternative Splicing and Transcript Diversity database". Genomics. 93 (3). United States: 213–20. doi:10.1016/j.ygeno.2008.11.003. PMID 19059335.
  2. ^ "Alternative Splicing Database Project | EBI". www.ebi.ac.uk. Archived from the original on 2011-12-27. Retrieved 2020-03-04.

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Alternative Splicing and Transcript Diversity database

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The Alternative Splicing and Transcript Diversity database (ASTD) was a database of transcript variants maintained by the European Bioinformatics Institute...

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Alternative splicing

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Alternative splicing, or alternative RNA splicing, or differential splicing, is an alternative splicing process during gene expression that allows a single...

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European Bioinformatics Institute

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Institute of Genomics, Chinese Academy of Sciences Alternative splicing and transcript diversity database BioSamples European Molecular Biology Organization...

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Transcriptomics technologies

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transcriptome, the sum of all of its RNA transcripts. The information content of an organism is recorded in the DNA of its genome and expressed through transcription...

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De novo transcriptome assembly

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transcripts, such as alternative splicing. Since a genome contains the sum of all introns and exons that may be present in a transcript, spliced variants that...

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Epitranscriptome

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alternative splicing compared to genes that code a single isoform. This is because alternatively spliced mRNAs are enriched in METTL3 binding sites. Splicing is...

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Intron

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tRNA precursors, and are removed by a tRNA splicing endonuclease. The exons are then linked together by a second protein, the tRNA splicing ligase. Note that...

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DNA microarray

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analysis); mapping each probe to the mRNA transcript that it measures (Annotation); the sheer volume of data and the ability to share it (Data warehousing)...

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RNA editing

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Eisenmenger W, et al. (January 2010). "Alternative splicing and extensive RNA editing of human TPH2 transcripts". PLOS ONE. 5 (1): e8956. Bibcode:2010PLoSO...

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RBM10

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In addition, RBM10 primary transcripts are subjected to alternative splicing at several exons by unidentified splicing regulators, leading to the generation...

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C7orf50

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three other transcripts encode isoform b, c, and d, respectively. The table below is representative of these transcripts. Alternatively, when the primary...

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CD44

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determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. Splice variants...

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Gene expression

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This so-called alternative splicing creates series of different transcripts originating from a single gene. Because these transcripts can be potentially...

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Muscarinic acetylcholine receptor M2

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receptor that in humans is encoded by the CHRM2 gene. Multiple alternatively spliced transcript variants have been described for this gene. It is Gi-coupled...

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TNNT2

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cardiomyopathy as well as with restrictive and dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific...

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Gene

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single large mRNAs, alternative splicing enables a single genomic region to encode multiple district products and trans-splicing concatenates mRNAs from...

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DNA annotation

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their start and stop codons, UTRs and alternative transcripts, and ideally should include information about the sequence alignments and gene predictions...

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CYP3A4

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now thought that this sequence represents a transcript variant of CYP3A4. Alternatively-spliced transcript variants encoding different isoforms have been...

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ARMH3

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strand of the long arm of chromosome 10. Its 26 alternatively spliced exons encode 5 potential transcript variants, the largest of which being 4101 base...

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Adenoviridae

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phases: an early and a late phase. In both phases, a primary transcript that is alternatively spliced to generate monocistronic mRNAs compatible with the host's...

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Tropomyosin 3

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tropomyosin in human fibroblasts: evidence for expression by an alternative RNA splicing mechanism". Proc. Natl. Acad. Sci. U.S.A. 82 (23): 7835–9. doi:10...

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