Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Not to be confused with Chloroacetic acid, Chloroacetyl chloride, Acetylcholine, or Actinium(III) chloride.
Acetyl chloride (CH3COCl) is an acyl chloride derived from acetic acid (CH3COOH). It belongs to the class of organic compounds called acid halides. It is a colorless, corrosive, volatile liquid. Its formula is commonly abbreviated to AcCl.
^Merck Index, 11th Edition, 79.
^Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book). Cambridge: The Royal Society of Chemistry. 2014. pp. 796–797. doi:10.1039/9781849733069-FP001. ISBN 978-0-85404-182-4.
Acetylchloride (CH3COCl) is an acyl chloride derived from acetic acid (CH3COOH). It belongs to the class of organic compounds called acid halides. It...
example of an acyl chloride is acetylchloride, CH3COCl. Acyl chlorides are the most important subset of acyl halides. Where the acyl chloride moiety takes...
variety of methods, most commonly with the use of acetic anhydride or acetylchloride, often in the presence of a tertiary or aromatic amine base. A typical...
industrial uses, but it is by far the oldest and best-known application. acetylchloride SOCl2 acetic acid (i) Li[AlH4], ether (ii) H3O+ ethanol Acetic acid...
acid. It can be produced by reacting phenol with acetic anhydride or acetylchloride. Phenyl acetate can be separated into phenol and an acetate salt, via...
methyl iodide in turn affords acetyl iodide, which reacts with acetate salts or acetic acid to give the product. Rhodium chloride in the presence of lithium...
strong acid catalyst will not form peracetic acid. As an alternative, acetylchloride and acetic anhydride can be used to generate a solution of the acid...
group. Triphenylmethyl chloride is commercially available. It may be prepared by the reaction of triphenylmethanol with acetylchloride, or by the Friedel–Crafts...
Trifluoroacetyl chloride (also known as TFAC) is a toxic gaseous chemical compound with the chemical formula C2ClF3O. TFAC is the perfluorinated version of acetyl chloride...
also be prepared from anhydrous cadmium acetate using hydrogen chloride or acetylchloride. Industrially, it is produced by the reaction of molten cadmium...
Trichloroacetyl chloride is the acyl chloride of trichloroacetic acid. It can be formed by reacting chlorine with acetylchloride or acetaldehyde in the...
Charles Frédéric Gerhardt treated the medicine sodium salicylate with acetylchloride to produce acetylsalicylic acid for the first time. Over the next 50...
Although far rarer in the laboratory than the related acetyl bromide and acetylchloride, acetyl iodide is produced, transiently at least, on a far larger...
permanganate or bleach), or by the hydrolysis of acetyl cyanide, formed by reaction of acetylchloride with potassium cyanide:[citation needed] CH3COCl...
cogenerates acetic acid. Acetylchloride. This reagent is also common in the laboratory, but its use cogenerates hydrogen chloride, which can be undesirable...
bond. Well-known acyl compounds are the acyl chlorides, such as acetylchloride (CH3COCl) and benzoyl chloride (C6H5COCl). These compounds, which are treated...
hydrogen chloride produces a mixture of acetylchloride and acetic acid: (CH3CO)2O + HCl → CH3COCl + CH3CO2H Common syntheses of acyl chlorides also entail...
nitrolysis reactions. It acetylates amines, akin to the behavior of acetylchloride: 2 NH 3 + CH 3 C ( O ) ONO 2 ⟶ NH 4 NO 3 + CH 3 CONH 2 {\displaystyle...
Friedel–Crafts acylation uses acetylchloride (CH3COCl) as the agent and aluminum chloride (AlCl3) as a catalyst to add an acetyl group to benzene: This reaction...
by the enzyme choline acetyltransferase from the compounds choline and acetyl-CoA. Cholinergic neurons are capable of producing ACh. An example of a central...
Aniline reacts with acyl chlorides or carboxylic anhydrides to give anilides. For example, reaction of aniline with acetylchloride provides acetanilide (CH3−CO−NH−C6H5)...
alcohol (in effect protecting the alcohol by acetylation): Acetyl halide, such as acetylchloride in the presence of a base like triethylamine Activated ester...
et sur le chlorure d'acétyle" (in French) (Note on aldehyde and on acetylchloride), Annales de chimie et de physique, 3rd series, 49 : 58–62, see p. 61...
prepared synthetically by Friedel-Crafts acylation of anisole with acetylchloride: It is used as a cigarette additive, a fragrance, and a flavoring in...
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