factor 1 is a protein that in humans is encoded by the ARF1 gene. ADP-ribosylation factor 1 (ARF1) is a member of the human ARF gene family. The family...
GTP but poorly or not at all to the GDP nucleotide. Structural studies of Arf1 and Arf6 have revealed that although these proteins feature the switch 1...
form symmetric trimers ("triads"). The curved triad structure positions the Arf1 molecules and cargo binding sites proximal to the membrane. The β′- and α-COP...
Golgi membrane, it must interact with a small GTPase called ARF1 (ADP ribosylation factor). ARF1 that is bound to GDP interacts with the golgi complex membrane...
+2-nt movement of the toeprint of the pre-termination complex. The archaeal aRF1–EF1α–GTP complex is similar. The triggering mechanism is similar to that...
John A G (2017-06-16). "9Å structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments". eLife. 6. doi:10...
necessary for the pre-coupling. It has also been shown to interact with Arf6 and ARF1. Muscarinic acetylcholine receptor GRCh38: Ensembl release 89: ENSG00000133019...
molecular biology, the arfaptin domain is a protein domain which interacts with ARF1, a small GTPase involved in vesicle budding at the Golgi complex and immature...
Jackson, Catherine L. (2005-03-01). "Dynamics of GBF1, a Brefeldin A-Sensitive Arf1 Exchange Factor at the Golgi". Molecular Biology of the Cell. 16 (3): 1213–1222...
is shown here. Exomer binds to 2 molecules of ADP-ribosylation factor 1 (Arf1) as shown in this figure. A hinge region of exomer is thought to be important...
sorting and membrane trafficking. CYTH2 exhibits GEP activity in vitro with ARF1, ARF3, and ARF6. CYTH2 protein is 83% homologous to CYTH1. Two transcript...
family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2, and ARF3), class II (ARF4 and ARF5) and class III (ARF6) and members...
α-l-arabinofuranosidase called Arf1, which accounts for almost all the arabinofuranosidase activity in the cells. Arf1 is a trimer or tetramer of between...
and membrane trafficking. CYTH4 exhibits GEP activity in vitro with both ARF1 and ARF5 but is inactive with ARF6. The CYTH4 and CYTH1 gene structures are...
mitochondria-ER contact sites is from the Golgi apparatus. Golgi contain ARF1 proteins localized on their membranes, which are capable of recruiting kinases...
Chavrier P (2005). "Golgi-localized GAP for Cdc42 functions downstream of ARF1 to control Arp2/3 complex and F-actin dynamics". Nat. Cell Biol. 7 (4): 353–64...
The protein encoded by this gene stimulates guanine nucleotide exchange on ARF1 and Rab proteins. This protein is thought to be involved in membrane transport...
Reiser G (October 2007). "p24A, a type I transmembrane protein, controls ARF1-dependent resensitization of protease-activated receptor-2 by influence on...
to interact with ADP-ribosylation factor 1 (ARF1). The encoded protein likely promotes hydrolysis of ARF1-bound GTP, which is required for the dissociation...
(via the CYFIP1 component of the complex) and Arf small GTPases (such as ARF1, ARF5, and ARF6 ) or the similar protein ARL1, which causes dissociation...
ADP-ribosylation factor protein 6 (ARF) functions, in addition to acting on ARF1. GRCh38: Ensembl release 89: ENSG00000008256 – Ensembl, May 2017 GRCm38:...
originally known as 'KIAA1110', under which name it was found to act as a GEF for Arf1 but not Arf6. It is related to the other Arf-GEF protein IQSEC1. "www.genenames...
which interacts with ADP-ribosylation factor 1 (ARF1). The encoded protein promotes hydrolysis of ARF1-bound GTP and is required for the dissociation of...
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