TMED2 information

TMED2
Identifiers
Aliases	TMED2, P24A, RNP24, p24, p24b1, p24beta1, transmembrane p24 trafficking protein 2
External IDs	MGI: 3704329 HomoloGene: 55991 GeneCards: TMED2
Gene location (Human)
Chr.	Chromosome 12 (human)
End	123,598,582 bp
RNA expression pattern
	Top expressed in
	parotid gland; ; corpus epididymis; ; pylorus; ; pericardium; ; trachea; ; caput epididymis; ; cardia; ; human penis; ; superior surface of tongue; ; lactiferous duct;
	n/a
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	transport vesicle; integral component of membrane; ER to Golgi transport vesicle membrane; Golgi apparatus; Golgi membrane; intracellular membrane-bounded organelle; Golgi cisterna membrane; zymogen granule membrane; membrane; endoplasmic reticulum; endoplasmic reticulum membrane; cytoplasmic vesicle membrane; cytoplasmic vesicle; COPI-coated vesicle; endoplasmic reticulum-Golgi intermediate compartment membrane; endoplasmic reticulum-Golgi intermediate compartment; COPI-coated vesicle membrane; COPII-coated ER to Golgi transport vesicle;
Biological process	vesicle cargo loading; neural tube closure; maternal placenta development; embryonic placenta development; COPII vesicle coating; endoplasmic reticulum to Golgi vesicle-mediated transport; heart looping; positive regulation of gene expression; somitogenesis; Golgi organization; post-anal tail morphogenesis; embryonic morphogenesis; multicellular organism growth; in utero embryonic development; protein transport; negative regulation of GTPase activity; COPI coating of Golgi vesicle; labyrinthine layer blood vessel development; vesicle-mediated transport; somite rostral/caudal axis specification; intracellular protein transport; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; protein localization to plasma membrane;
	Sources:Amigo / QuickGO
Orthologs
	10959
	100862175
	ENSG00000086598
	n/a
	Q15363
	Q9R0Q3
	NM_006815; NM_001321445
	XM_003945446
	NP_001308374; NP_006806
	NP_062744; NP_001390182; NP_001390186
	Wikidata
View/Edit Human	View/Edit Mouse

Transmembrane emp24 domain-containing protein 2 is a protein that in humans is encoded by the TMED2 gene.^[4]^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000086598 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Blum R, Feick P, Puype M, Vandekerckhove J, Klengel R, Nastainczyk W, Schulz I (July 1996). "Tmp21 and p24A, two type I proteins enriched in pancreatic microsomal membranes, are members of a protein family involved in vesicular trafficking". The Journal of Biological Chemistry. 271 (29): 17183–9. doi:10.1074/jbc.271.29.17183. PMID 8663407.
^ "Entrez Gene: TMED2 transmembrane emp24 domain trafficking protein 2".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000086598 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8663407-4] Blum R, Feick P, Puype M, Vandekerckhove J, Klengel R, Nastainczyk W, Schulz I (July 1996). "Tmp21 and p24A, two type I proteins enriched in pancreatic microsomal membranes, are members of a protein family involved in vesicular trafficking". The Journal of Biological Chemistry. 271 (29): 17183–9. doi:10.1074/jbc.271.29.17183. PMID 8663407.

[entrez-5] "Entrez Gene: TMED2 transmembrane emp24 domain trafficking protein 2".

TMED2 information

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