Washed red blood cells are red blood cells which have had most of the plasma, platelets and white blood cells removed and replaced with saline or another type of preservation solution.[1][2] The most common reason for using washed red blood cells in transfusion medicine is to prevent the recurrence of severe allergic transfusion reactions that do not respond to medical treatment. The usual cause of these allergic reactions is proteins in the donor plasma.[3] These proteins are removed by the process of washing the red blood cells.
^Albiston B (October 2011). "Guideline for Washed Red Blood Cells in Nova Scotia" (PDF). Nova Scotia.
^Lu M, Lezzar DL, Vörös E, Shevkoplyas SS (2019). "Traditional and emerging technologies for washing and volume reducing blood products". Journal of Blood Medicine. 10: 37–46. doi:10.2147/JBM.S166316. PMC 6322496. PMID 30655711.
^Cite error: The named reference :1 was invoked but never defined (see the help page).
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in 1972. The processor washed fresh blood or frozen, thawed blood. In the case of frozen, thawed blood, the blood was washed to remove the cryogenic...
clinical complications. The washed system requires a properly trained and clinically skilled operator. It returns only redbloodcells suspended in saline and...
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antibody-sensitized redbloodcells (RBC) and may or may not exhibit phagocytosis (ingestion) and destroy the donor redbloodcells. If monocytes destroy...
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