Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Vernolic acid (leukotoxin B[1]) is a long chain fatty acid that is monounsaturated and contains an epoxide. It is the R,R-cis epoxide derived from the C12–C13 alkene of linoleic acid.[2] Vernolic acid was first definitively characterized in 1954.[3] It is a major component in vernonia oil, which is produced in abundance by the genera Vernonia and Euphorbia and is a potentially useful biofeedstock.
^National Center for Biotechnology Information. "PubChem Compound Summary for CID 6449780, Vernolic acid". PubChem. Retrieved 29 May 2023.
^Metzger, J. O.; Bornscheuer, U. (2006). "Lipids as renewable resources: current state of chemical and biotechnological conversion and diversification". Applied Microbiology and Biotechnology. 71 (1): 13–22. doi:10.1007/s00253-006-0335-4. PMID 16604360. S2CID 28601501.
^Gunstone FD (1954). "Fatty acids. Part II. The nature of the oxygenated acid present in Vernonia anthelmintica (Willd.) seed oil". Journal of the Chemical Society. 1954: 1611–1616. doi:10.1039/JR9540001611.
Vernolicacid (leukotoxin B) is a long chain fatty acid that is monounsaturated and contains an epoxide. It is the R,R-cis epoxide derived from the C12–C13...
epoxide products viz., its 12,13-epoxide, vernolicacid, and its 9,10-epoxide, coronaric acid. These linoleic acid products are implicated in human physiology...
of Vernonia have the highest oil content, up to 41.9% with up to 80% vernolicacid, and is used in paint formulations, coatings plasticizers, and as a...
a few other plants (such as some species of Vernonia), it contains vernolicacid, a vegetable oil with commercial applications. The genus is named after...
acids. This (+) and (-) optical mixture is often termed vernolicacid when studied in plants and leukotoxin when studied in mammals. Coronaric acid is...
acid, and ellagic acid (alizarine yellow). A C20 homolog of vernolicacid named alchornoic acid can be found in the seed oil. The plant is cultivated for...
sEH also metabolizes the epoxides of linoleic acid viz., Vernolicacid (leukotoxins) and Coronaric acids (isoleukotoxins) to their corresponding diols...
3-oxo-5αH,8βH-eudesma-1,4(15),7(11)-trien-8,12-olide, can work with vernolicacid and other compounds in plants to reduce inflammation. Some plants containing...
refer to: Coronaric acid, or isoleukotoxin 9-Hydroxyoctadecadienoic acid 13-Hydroxyoctadecadienoic acid (13-HODE) Vernolicacid (leukotoxin) This set...
fatty acids metabolites caused by dietary omega-3 fatty acids. CYP2C9 may also metabolize linoleic acid to the potentially very toxic products, vernolic acid...
and 12R,13S-epoxy-9(Z)-octadecenoic acids; this set of optical isomers is also termed vernolicacid, linoleic acid 12:13-oxide, and leukotoxin. CYPC2C9...
from the seeds of the Vernonia galamensis. It is composed of 73–80% vernolicacid, which can be used to make epoxies for manufacturing adhesives, varnishes...
source of vernonia oil, which is rich in a useful epoxy fatty acid called vernolicacid and is used to make plastics, rubbery coatings, and drying agents...
12-Hexadecadien-1-ol. Butenandt then synthesized bombycol from vernolicacid [(12R,13S)-Epoxy-9-cis-octadecenoic acid] in several steps via diol formation, its cleavage...
epoxyeicosatrienoic acids. In its hydrolysis one isomer of vernolicacid (12S,13R-epoxy-cis-9-octadecenoic acid) 12S,13R-epoxy-cis-9-octadecenoic acid + H2O → 12S...
9,10-epoxide isomers termed vernolicacids or leukotoxins and two different 12,13-epoxides isomers termed coronaric acids or isoleukotoxins. They metabolize...
epoxydocosapentaenoic acids (also termed EDPs); and 3) linoleic acid to its various epoxides, i.e. vernolicacid (also termed leukotoxin) and coronaric acid (also termed...
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