CYP2S1 information

CYP2S1
Identifiers
Aliases	CYP2S1, CYPIIS1, cytochrome P450 family 2 subfamily S member 1
External IDs	OMIM: 611529; MGI: 1921384; HomoloGene: 75274; GeneCards: CYP2S1; OMA:CYP2S1 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	41,207,539 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	25,516,338 bp
RNA expression pattern
	Top expressed in
	jejunal mucosa; ; duodenum; ; rectum; ; body of stomach; ; tibialis anterior muscle; ; monocyte; ; gastric mucosa; ; appendix; ; bronchial epithelial cell; ; oral cavity;
	Top expressed in
	epithelium of stomach; ; pyloric antrum; ; mucous cell of stomach; ; esophagus; ; right lung lobe; ; submandibular gland; ; colon; ; left colon; ; parotid gland; ; duodenum;
	More reference expression data
	n/a
Gene ontology
Molecular function	iron ion binding; oxidoreductase activity; aromatase activity; protein binding; heme binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; metal ion binding; monooxygenase activity; retinoic acid 4-hydroxylase activity; arachidonic acid epoxygenase activity; steroid hydroxylase activity;
Cellular component	organelle membrane; endoplasmic reticulum membrane; endoplasmic reticulum; membrane; intracellular membrane-bounded organelle; cytoplasm;
Biological process	epoxygenase P450 pathway; organic acid metabolic process; xenobiotic metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	29785
	74134
	ENSG00000167600
	ENSMUSG00000040703
	Q96SQ9
	Q9DBX6
	NM_030622
	NM_028775
	NP_085125
	NP_083051
	Wikidata
View/Edit Human	View/Edit Mouse

Cytochrome P450 2S1 is a protein that in humans is encoded by the CYP2S1 gene.^[5]^[6] The gene is located in chromosome 19q13.2 within a cluster including other CYP2 family members such as CYP2A6, CYP2A13, CYP2B6, and CYP2F1.^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000167600 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000040703 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Rylander T, Neve EP, Ingelman-Sundberg M, Oscarson M (February 2001). "Identification and tissue distribution of the novel human cytochrome P450 2S1 (CYP2S1)". Biochemical and Biophysical Research Communications. 281 (2): 529–35. doi:10.1006/bbrc.2001.4390. PMID 11181079.
^ "Entrez Gene: CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1".
^ Saarikoski ST, Rivera SP, Hankinson O, Husgafvel-Pursiainen K (September 2005). "CYP2S1: a short review". Toxicology and Applied Pharmacology. 207 (2 Suppl): 62–9. doi:10.1016/j.taap.2004.12.027. PMID 16054184.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000167600 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000040703 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11181079-5] Rylander T, Neve EP, Ingelman-Sundberg M, Oscarson M (February 2001). "Identification and tissue distribution of the novel human cytochrome P450 2S1 (CYP2S1)". Biochemical and Biophysical Research Communications. 281 (2): 529–35. doi:10.1006/bbrc.2001.4390. PMID 11181079.

[entrez-6] "Entrez Gene: CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1".

[Saarikoski_2005-7] Saarikoski ST, Rivera SP, Hankinson O, Husgafvel-Pursiainen K (September 2005). "CYP2S1: a short review". Toxicology and Applied Pharmacology. 207 (2 Suppl): 62–9. doi:10.1016/j.taap.2004.12.027. PMID 16054184.

CYP2S1 information

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