Sesquiterpene lactones (SLs) are a class of sesquiterpenoids that contain a lactone ring. They are most often found in plants of the family Asteraceae (daisies, asters). Other plant families with SLs are Umbelliferae (celery, parsley, carrots) and Magnoliaceae (magnolias). A collection of colorless, lipophilic solids, SLs are a rich source of drugs.[1] They can be allergenic and toxic in grazing livestock[2] causing severe neurological problems in horses. Some are also found in corals of the order Alcyonacea.
^Ghantous, Akram; Gali-Muhtasib, Hala; Vuorela, Heikki; Saliba, Najat A.; Darwiche, Nadine (2010). "What Made Sesquiterpene Lactones Reach Cancer Clinical Trials?". Drug Discovery Today. 15 (15–16): 668–678. doi:10.1016/0305-1978(86)90101-8. PMID 20541036.
^"Sesquiterpene Lactones and their toxicity to livestock". Cornell CALS. Cornell University. Retrieved December 29, 2018.
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Sesquiterpenelactones (SLs) are a class of sesquiterpenoids that contain a lactone ring. They are most often found in plants of the family Asteraceae...
provides the sesquiterpenoid farnesol. Sesquiterpenelactones are a common class of sesquiterpenoids that contain a lactone ring, hence the name. They are found...
economists, and atmospheric and agricultural modellers. Three sesquiterpenelactones isolated from the aerial parts of Ambrosia artemisiifolia were identified...
efficient than using the plant. Artemisinin and its derivatives are all sesquiterpenelactones containing an unusual peroxide bridge. This endoperoxide 1,2,4-trioxane...
analgesic effect, acting on the central nervous system. It is a sesquiterpenelactone, and is a component of lactucarium, derived from the plant Lactuca...
4a,7a,8,9,9a-octahydroazuleno[6,5-b]furan-2,5-dione, is a toxic sesquiterpenelactone which can be found in several plants such as Arnica montana and...
Arglabin is a sesquiterpenelactone belonging to the guaianolide subclass bearing a 5,7,5-tricyclic ring system which is known to inhibit farnesyl transferase...
Parthenin is a chemical compound classified as a sesquiterpenelactone. It has been isolated from Parthenium hysterophorus. It is genotoxic, allergenic...
(+)-Costunolide is a naturally occurring sesquiterpenelactone, first isolated in Saussurea costus roots in 1960. It is also found in lettuce. It is synthesized...
Artemisin is a sesquiterpenelactone, similar in structure to α-santonin. Artemisia (genus), hardy herbaceous plants and shrubs known for the powerful...
commonly featured in medical and phytochemical journals because the sesquiterpenelactone compounds contained within them are an important cause of allergic...
Parthenolide is a sesquiterpenelactone of the germacranolide class which occurs naturally in the plant feverfew (Tanacetum parthenium), after which it...
caused in horses ingesting Russian knapweed for prolonged periods. A sesquiterpenelactone, repin, in the plant is likely responsible for this toxicity. The...
absinthium. Absinthin's (1) complex structure is classified as a sesquiterpenelactone, meaning it belongs to a large category of natural products chemically...
artemether to be an effective antimalarial drug. Artemisinin is a sesquiterpenelactone with an endoperoxide bridge and has been produced as an antimalarial...
(1975). Toxicity and milk bittering properties of tenulin, the major sesquiterpenelactone constituent of Helenium amarum (bitter sneezeweed). J Agric Food...
Xanthium strumarium (Asteracae) plant. It is classified as a natural sesquiterpenelactone. Xanthatin is believed to have anti-inflammatory, anti-tumour, anti-microbial...
bacteria and fungi. The leaves contain coumarins and sesquiterpenelactones. The sesquiterpenes are known to be costunolide, parthenolide, costunolide...
In organic chemistry, a guaianolide is a type of sesquiterpenelactone consisting of a gamma-lactone and either a cyclopentane or cyclopentene, both fused...
that forms a white crystalline solid and belongs to the group of sesquiterpenelactones. It is found in some varieties of lettuce and is an ingredient of...
phenolic acids, coumarins, sterols, carotenoids, vitamins, and sesquiterpenelactones, among many others. Examples of the phytochemicals include vulgarin...
C15H18O4 may refer to: Artemisin, a sesquiterpenelactone Helenalin, a sesquiterpenelactone Parthenin, a sesquiterpenelactone Plicatin A, a hydroxycinnamic...
anti-inflammatory agent for respiratory tract diseases, and several of its sesquiterpenelactone constituents were identified to have anti-inflammatory effect in...
which contribute to the plant's bitterness are primarily the two sesquiterpenelactones, lactucin and lactucopicrin. Other components are aesculetin, aesculin...
consume the mushroom. The lactarane-type sesquiterpenelactone 15-hydroxyblennin A is one of several sesquiterpenes produced by the species. Other lactaranes...
10 minutes. After that, it is strained and mixed with honey. A sesquiterpenelactone from afra had cytotoxicity. It has a lot of genetic variation, especially...
Cnicin is a sesquiterpenelactone, esterified with a substituted acrylic acid, and belonging to the germacranolide class of natural products. It is mainly...
triterpenes α- and β-amyrin, the eudesmane derivative β-selinene, and the sesquiterpenelactone 8β-hydroxyasterolide. Domestic cats and dogs often select and ingest...
Sclareolide is a sesquiterpenelactone natural product derived from various plant sources including Salvia sclarea, Salvia yosgadensis, and cigar tobacco...