Image showing the mechanism of activation of type 1 hypersensitivity in a mast cell.
Specialty
Immunology
Type I hypersensitivity (or immediate hypersensitivity), in the Gell and Coombs classification of allergic reactions, is an allergic reaction provoked by re-exposure to a specific type of antigen referred to as an allergen.[1] Type I is distinct from type II, type III and type IV hypersensitivities. The relevance of the Gell and Coombs classification of allergic reactions has been questioned in the modern-day understanding of allergy, and it has limited utility in clinical practice.[2]
Exposure may be by ingestion, inhalation, injection, or direct contact.
^med/1101 at eMedicine
^Descotes, Jacques; Choquet-Kastylevsky, Geneviève (February 2001). "Gell and Coombs's classification: is it still valid?". Toxicology. 158 (1–2): 43–49. doi:10.1016/S0300-483X(00)00400-5. PMID 11164991.
and 28 Related for: Type I hypersensitivity information
TypeIhypersensitivity (or immediate hypersensitivity), in the Gell and Coombs classification of allergic reactions, is an allergic reaction provoked...
Hypersensitivity (also called hypersensitivity reaction or intolerance) is an abnormal physiological condition in which there is an undesirable and adverse...
Coombs defined type III hypersensitivity reactions as those involving soluble immune complexes (in contrast to type II hypersensitivities which involve...
Type II hypersensitivity, in the Gell and Coombs classification of allergic reactions, is an antibody mediated process in which IgG and IgM antibodies...
clarified as a true allergy, was restricted to typeIhypersensitivities (also called immediate hypersensitivity), which are characterized as rapidly developing...
a hypersensitivity immune reaction causing inflammation of the airspaces (alveoli) and small airways (bronchioles) within the lung. Hypersensitivity pneumonitis...
asthma are more likely to be severely affected. It is due to a typeIhypersensitivity reaction of the immune system in susceptible individuals. The allergy...
terms, an allergen is an antigen that is capable of stimulating a type-Ihypersensitivity reaction in atopic individuals through immunoglobulin E (IgE) responses...
The allergic march (also called atopic march) is a medical term used to explain the natural history of atopic manifestations. The allergic march is characterized...
Atopic dermatitis (AD), also known as atopic eczema, is a long-term type of inflammation of the skin (dermatitis). It results in itchy, red, swollen, and...
within 20 minutes is considered positive (immediate hypersensitivity). Delayed hypersensitivity reactions usually read after 18–24 hours. The test is...
an essential role in typeIhypersensitivity, which manifests in various allergic diseases, such as allergic asthma, most types of sinusitis, allergic...
mutilation Type 1 personality TypeIhypersensitivity (or immediate hypersensitivity), an allergic reaction Type 1 diesel locomotives US F1 Type 1, 2010...
activates the mast cells, releasing a variety of mediators. This typeIhypersensitivity reaction is the basis of the symptoms of allergic reactions, which...
attempt to immunise the dog, which instead developed a severe reaction (hypersensitivity). In 1902, they repeated the injections in their laboratory and found...
response in cases that are annoying to the person.[citation needed] This type of hives can occur right away, precisely after a pressure stimulus or as...
prednisone will be prescribed to prevent a possible late-phase typeIhypersensitivity reaction. Severe allergic reactions (anaphylaxis) may require treatment...
Electromagnetic hypersensitivity (EHS) is a claimed sensitivity to electromagnetic fields, to which negative symptoms are attributed. EHS has no scientific...
termed hypersensitivity to mosquito bites, are excessive reactions of varying severity to mosquito bites. They are allergic hypersensitivity reactions...
for the rapid administration of nerve gas antidotes in kits like the Mark I NAAK. The first modern epinephrine autoinjector, the EpiPen, was invented...
reactions to latex range from TypeIhypersensitivity, the most serious form of reaction, to Type IV hypersensitivity. Rate of onset is directly proportional...
is classified as a Type IV hypersensitivity reaction. This classification differs from the more prevalent TypeIhypersensitivity (e.g., hay fever), where...
Allergic rhinitis, of which the seasonal type is called hay fever, is a type of inflammation in the nose that occurs when the immune system overreacts...
Egg allergy is an immune hypersensitivity to proteins found in chicken eggs, and possibly goose, duck, or turkey eggs. Symptoms can be either rapid or...
to, a hypersensitivity response occurs. Hypersensitivity is believed to be the cause of allergy and some auto-immune disease. Hypersensitivity reactions...
and other additives. A patch test relies on the principle of a type IV hypersensitivity reaction. The first step in becoming allergic is sensitization...